Patel, Rakesh P.

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

Cosby, K., Partovi, K. S., Crawford, J. H., Patel, R. P., Reiter, C. D., Martyr, S., Yang, B. K., Waclawiw, M. A., Zalos, G., Xu, X., et al. (2003) · Nature Medicine

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 1,807

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

Duranski, M. R., Greer, J. J. M., Dejam, A., Jaganmohan, S., Hogg, N., Langston, W., Patel, R. P., Yet, S.-F., Wang, X., Kevil, C. G., et al. (2005) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 674

Nitrate and nitrite in biology, nutrition and therapeutics

Lundberg, J. O., Gladwin, M. T., Ahluwalia, A., Benjamin, N., Bryan, N. S., Butler, A., Cabrales, P., Fago, A., Feelisch, M., Ford, P. C., et al. (2009) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 617

The emerging biology of the nitrite anion

Gladwin, M. T., Schechter, A. N., Kim-Shapiro, D. B., Patel, R. P., Hogg, N., Shiva, S., Cannon, R. O., Kelm, M., Wink, D. A., Espey, M. G., et al. (2005) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 609

Biological aspects of reactive nitrogen species

Patel, R. P., McAndrew, J., Sellak, H., White, C. R., Jo, H., Freeman, B. A., & Darley-Usmar, V. M. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 498

Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease

Aslan, M., Ryan, T. M., Adler, B., Townes, T. M., Parks, D. A., Thompson, J. A., Tousson, A., Gladwin, M. T., Patel, R. P., Tarpey, M. M., et al. (2001) · Proceedings of the National Academy of Sciences

Hemoglobinopathies and Related DisordersNitric Oxide and Endothelin Effects

Cited by 391

Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators

Cui, T., Schopfer, F. J., Zhang, J., Chen, K., Ichikawa, T., Baker Paul, R. S., Batthyany, C., Chacko, B. K., Feng, X., Patel, R. P., et al. (2006) · Journal of Biological Chemistry

Fatty Acid Research and HealthInflammatory mediators and NSAID effects

Cited by 351

Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation

Gladwin, M. T., Raat, N. J. H., Shiva, S., Dezfulian, C., Hogg, N., Kim-Shapiro, D. B., & Patel, R. P. (2006) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 329

The Reaction between Nitrite and Deoxyhemoglobin

Huang, K. T., Keszler, A., Patel, N., Patel, R. P., Gladwin, M. T., Kim-Shapiro, D. B., & Hogg, N. (2005) · Journal of Biological Chemistry

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 253

Redox Reactions of Hemoglobin and Myoglobin: Biological and Toxicological Implications

Alayash, A. I., Patel, R. P., & Cashon, R. E. (2001) · Antioxidants & Redox Signaling

Hemoglobin structure and functionMetal-Catalyzed Oxygenation Mechanisms

Cited by 243

Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation

Lang, J. D., Teng, X., Chumley, P., Crawford, J. H., Isbell, T. S., Chacko, B. K., Liu, Y., Jhala, N., Crowe, D. R., Smith, A. B., et al. (2007) · Journal of Clinical Investigation

Organ Transplantation Techniques and OutcomesTransplantation: Methods and Outcomes

Cited by 224

Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin

Basu, S., Grubina, R., Huang, J., Conradie, J., Huang, Z., Jeffers, A., Jiang, A., He, X., Azarov, I., Seibert, R., et al. (2007) · Nature Chemical Biology

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 224

A mitochondria-targeted S -nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury

Prime, T. A., Blaikie, F. H., Evans, C., Nadtochiy, S. M., James, A. M., Dahm, C. C., Vitturi, D. A., Patel, R. P., Hiley, C. R., Abakumova, I., et al. (2009) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsMitochondrial Function and Pathology

Cited by 222

Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis

Kumar, D., Branch, B. G., Pattillo, C. B., Hood, J., Thoma, S., Simpson, S., Illum, S., Arora, N., Chidlow, J. H., Langston, W., et al. (2008) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsAngiogenesis and VEGF in Cancer

Cited by 187

Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species

Cooper, C. E., Patel, R. P., Brookes, P. S., & Darley-Usmar, V. M. (2002) · Trends in Biochemical Sciences

Redox biology and oxidative stressSulfur Compounds in Biology

Cited by 180

SNO-hemoglobin is not essential for red blood cell–dependent hypoxic vasodilation

Isbell, T. S., Sun, C.-W., Wu, L.-C., Teng, X., Vitturi, D. A., Branch, B. G., Kevil, C. G., Peng, N., Wyss, J. M., Ambalavanan, N., et al. (2008) · Nature Medicine

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 157

Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype

Sansbury, B. E., Cummins, T. D., Tang, Y., Hellmann, J., Holden, C. R., Harbeson, M. A., Chen, Y., Patel, R. P., Spite, M., Bhatnagar, A., et al. (2012) · Circulation Research

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 156

Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease

Crawford, J. H., Chacko, B. K., Pruitt, H. M., Piknova, B., Hogg, N., & Patel, R. P. (2004) · Blood

Nitric Oxide and Endothelin EffectsSepsis Diagnosis and Treatment

Cited by 111

Mechanisms of the interaction of nitroxyl with mitochondria

SHIVA, S., CRAWFORD, J. H., RAMACHANDRAN, A., CEASER, E. K., HILLSON, T., BROOKES, P. S., PATEL, R. P., & DARLEY-USMAR, V. M. (2004) · Biochemical Journal

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 78

Effects of sodium nitrite on ischemia–reperfusion injury in the rat kidney

Basireddy, M., Isbell, T. S., Teng, X., Patel, R. P., & Agarwal, A. (2006) · American Journal of Physiology-Renal Physiology

Acute Kidney Injury ResearchNitric Oxide and Endothelin Effects

Cited by 72

Pathways Linking Oral Bacteria, Nitric Oxide Metabolism, and Health

Morou-Bermúdez, E., Torres-Colón, J. E., Bermúdez, N. S., Patel, R. P., & Joshipura, K. J. (2022) · Journal of Dental Research

Oral microbiology and periodontitis researchGut microbiota and health

Cited by 70

The potential role of the red blood cell in nitrite-dependent regulation of blood flow

Patel, R. P., Hogg, N., & Kim-Shapiro, D. B. (2011) · Cardiovascular Research

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 70

Hemoglobin mediated nitrite activation of soluble guanylyl cyclase

Jeffers, A., Xu, X., Huang, K. T., Cho, M., Hogg, N., Patel, R. P., & Kim-Shapiro, D. B. (2005) · Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 67

Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway

Venkatesh, P. K., Pattillo, C. B., Branch, B., Hood, J., Thoma, S., Illum, S., Pardue, S., Teng, X., Patel, R. P., & Kevil, C. G. (2010) · Cardiovascular Research

Angiogenesis and VEGF in CancerNitric Oxide and Endothelin Effects

Cited by 64