Reddel, Roger R.

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

Bryan, T. M., Englezou, A., Dalla-Pozza, L., Dunham, M. A., & Reddel, R. R. (1997) · Nature Medicine

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,292

Telomere elongation in immortal human cells without detectable telomerase activity

Bryan, T. M., Englezou, A., Gupta, J., Bacchetti, S., & Reddel, R. R. (1995) · The EMBO Journal

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,279

Whole-genome landscape of pancreatic neuroendocrine tumours

Initiative, A. P. C. G., Scarpa, A., Chang, D. K., Nones, K., Corbo, V., Patch, A.-M., Bailey, P., Lawlor, R. T., Johns, A. L., Miller, D. K., et al. (2017) · Nature

Neuroendocrine Tumor Research AdvancesPancreatic and Hepatic Oncology Research

Cited by 999

Telomere maintenance by recombination in human cells

Dunham, M. A., Neumann, A. A., Fasching, C. L., & Reddel, R. R. (2000) · Nature Genetics

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 879

Protein Composition of Catalytically Active Human Telomerase from Immortal Cells

Cohen, S. B., Graham, M. E., Lovrecz, G. O., Bache, N., Robinson, P. J., & Reddel, R. R. (2007) · Science

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 669

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

Lovejoy, C. A., Li, W., Reisenweber, S., Thongthip, S., Bruno, J., de Lange, T., De, S., Petrini, J. H. J., Sung, P. A., Jasin, M., et al. (2012) · PLoS Genetics

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 629

Check your cultures! A list of cross‐contaminated or misidentified cell lines

Capes‐Davis, A., Theodosopoulos, G., Atkin, I., Drexler, H. G., Kohara, A., MacLeod, R. A. F., Masters, J. R., Nakamura, Y., Reid, Y. A., Reddel, R. R., et al. (2010) · International Journal of Cancer

Viral Infectious Diseases and Gene Expression in InsectsMicrobial infections and disease research

Cited by 520

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions

Cesare, A. J., Kaul, Z., Cohen, S. B., Napier, C. E., Pickett, H. A., Neumann, A. A., & Reddel, R. R. (2009) · Nature Structural & Molecular Biology

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 263

Five dysfunctional telomeres predict onset of senescence in human cells

Kaul, Z., Cesare, A. J., Huschtscha, L. I., Neumann, A. A., & Reddel, R. R. (2012) · The EMBO Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 225

Molecular mechanisms of activity and derepression of alternative lengthening of telomeres

Pickett, H. A., & Reddel, R. R. (2015) · Nature Structural & Molecular Biology

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 203

Alternative lengthening of telomeres in normal mammalian somatic cells

Neumann, A. A., Watson, C. M., Noble, J. R., Pickett, H. A., Tam, P. P. L., & Reddel, R. R. (2013) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 137

NuRD–ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination

Conomos, D., Reddel, R. R., & Pickett, H. A. (2014) · Nature Structural & Molecular Biology

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 129

The wide-ranging clinical implications of the Short Telomere Syndromes

Barbaro, P. M., Ziegler, D. S., & Reddel, R. R. (2016) · Internal Medicine Journal

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 40

Transformer-based deep learning integrates multi-omic data with cancer pathways

Cai, Z., Poulos, R. C., Aref, A., Robinson, P. J., Reddel, R. R., & Zhong, Q. (2022) · Cancer Research Communications

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 36

DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

Cai, Z., Poulos, R. C., Aref, A., Robinson, P. J., Reddel, R. R., & Zhong, Q. (2024) · Cancer Research Communications

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 36

CRISPR screens identify gene targets at breast cancer risk loci

Tuano, N. K., Beesley, J., Manning, M., Shi, W., Perlaza-Jimenez, L., Malaver-Ortega, L. F., Paynter, J. M., Black, D., Civitarese, A., McCue, K., et al. (2023) · Genome Biology

CRISPR and Genetic EngineeringGenetic Associations and Epidemiology

Cited by 30