Blakely, Randy D.

Pharmacological profile of antidepressants and related compounds at human monoamine transporters

Tatsumi, M., Groshan, K., Blakely, R. D., & Richelson, E. (1997) · European Journal of Pharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 939

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

Pacholczyk, T., Blakely, R. D., & Amara, S. G. (1991) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 933

A transient placental source of serotonin for the fetal forebrain

Bonnin, A., Goeden, N., Chen, K., Wilson, M. L., King, J., Shih, J. C., Blakely, R. D., Deneris, E. S., & Levitt, P. (2011) · Nature

Neurotransmitter Receptor Influence on BehaviorTryptophan and brain disorders

Cited by 608

Orthostatic Intolerance and Tachycardia Associated with Norepinephrine-Transporter Deficiency

Shannon, J. R., Flattem, N. L., Jordan, J., Jacob, G., Black, B. K., Biaggioni, I., Blakely, R. D., & Robertson, D. (2000) · New England Journal of Medicine

Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control

Cited by 594

The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters

Zhu, C.-B., Blakely, R. D., & Hewlett, W. A. (2006) · Neuropsychopharmacology

Tryptophan and brain disordersNeurotransmitter Receptor Influence on Behavior

Cited by 549

Molecular Physiology of Norepinephrine and Serotonin Transporters

Blakely, R. D., De Felice, L. J., & Hartzell, H. C. (1994) · Journal of Experimental Biology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 404

Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors

Sutcliffe, J. S., Delahanty, R. J., Prasad, H. C., McCauley, J. L., Han, Q., Jiang, L., Li, C., Folstein, S. E., & Blakely, R. D. (2005) · The American Journal of Human Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 392

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

Veenstra-VanderWeele, J., Muller, C. L., Iwamoto, H., Sauer, J. E., Owens, W. A., Shah, C. R., Cohen, J., Mannangatti, P., Jessen, T., Thompson, B. J., et al. (2012) · Proceedings of the National Academy of Sciences

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 333

Interleukin-1 Receptor Activation by Systemic Lipopolysaccharide Induces Behavioral Despair Linked to MAPK Regulation of CNS Serotonin Transporters

Zhu, C.-B., Lindler, K. M., Owens, A. W., Daws, L. C., Blakely, R. D., & Hewlett, W. A. (2010) · Neuropsychopharmacology

Tryptophan and brain disordersNeurotransmitter Receptor Influence on Behavior

Cited by 317

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity

Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K. Y., Foster, J. A., Peñagarikano, O., et al. (2015) · Molecular Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 288

Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits

Kelly, E., Meng, F., Fujita, H., Morgado, F., Kazemi, Y., Rice, L. C., Ren, C., Escamilla, C. O., Gibson, J. M., Sajadi, S., et al. (2020) · Nature Neuroscience

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 280

P38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process

Zhu, C.-B., Carneiro, A. M., Dostmann, W. R., Hewlett, W. A., & Blakely, R. D. (2005) · Journal of Biological Chemistry

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 228

Interactions between integrin αIIbβ3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans

Carneiro, A. M. D., Cook, E. H., Murphy, D. L., & Blakely, R. D. (2008) · Journal of Clinical Investigation

Platelet Disorders and TreatmentsCell Adhesion Molecules Research

Cited by 180

Excess of serotonin (5-HT) alters the segregation of ispilateral and contralateral retinal projections in monoamine oxidase A knock-out mice: possible role of 5-HT uptake in retinal ganglion cells during development

Upton, A. L., Salichon, N., Lebrand, C., Ravary, A., Blakely, R., Seif, I., & Gaspar, P. (1999) · The Journal of Neuroscience

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 173

Vesicular and Plasma Membrane Transporters for Neurotransmitters

Blakely, R. D., & Edwards, R. H. (2012) · Cold Spring Harbor Perspectives in Biology

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 169

Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function

Margolis, K. G., Li, Z., Stevanovic, K., Saurman, V., Israelyan, N., Anderson, G. M., Snyder, I., Veenstra-VanderWeele, J., Blakely, R. D., & Gershon, M. D. (2016) · Journal of Clinical Investigation

Autism Spectrum Disorder ResearchCongenital gastrointestinal and neural anomalies

Cited by 139

Psychiatric profile and attention deficits in postural tachycardia syndrome

Raj, V, Haman, K. L., Raj, S. R., Byrne, D., Blakely, R. D., Biaggioni, I., Robertson, D., & Shelton, R. C. (2009) · Journal of Neurology, Neurosurgery & Psychiatry

Cardiovascular Syncope and Autonomic DisordersPsychosomatic Disorders and Their Treatments

Cited by 131

Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

Veenstra-VanderWeele, J., & Blakely, R. D. (2012) · Neuropsychopharmacology

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 128

Evidence for Biphasic Effects of Protein Kinase C on Serotonin Transporter Function, Endocytosis, and Phosphorylation

Jayanthi, L. D., Samuvel, D. J., Blakely, R. D., & Ramamoorthy, S. (2005) · Molecular Pharmacology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 123

Chronic Stress Increases the Plasmalemmal Distribution of the Norepinephrine Transporter and the Coexpression of Tyrosine Hydroxylase in Norepinephrine Axons in the Prefrontal Cortex

Miner, L. H., Jedema, H. P., Moore, F. W., Blakely, R. D., Grace, A. A., & Sesack, S. R. (2006) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 107

Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters

Bermingham, D. P., & Blakely, R. D. (2016) · Pharmacological Reviews

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 97

Familial orthostatic tachycardia due to norepinephrine transporter deficiency

ROBERTSON, D., FLATTEM, N., TELLIOGLU, T., CARSON, R., GARLAND, E., SHANNON, J. R., JORDAN, J., JACOB, G., BLAKELY, R. D., & BIAGGIONI, I. (2001) · Annals of the New York Academy of Sciences

Cardiovascular Syncope and Autonomic DisordersCardiac electrophysiology and arrhythmias

Cited by 64

An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells

Brindley, R. L., Bauer, M. B., Blakely, R. D., & Currie, K. P. M. (2016) · Neuropharmacology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 26

A social encounter drives gene expression changes linked to neuronal function, brain development, and related disorders in mice expressing the serotonin transporter Ala56 variant

O’Reilly, K. C., Anacker, A. M. J., Rogers, T. D., Forsberg, C. G., Wang, J., Zhang, B., Blakely, R. D., & Veenstra-VanderWeele, J. (2020) · Neuroscience Letters

Neurotransmitter Receptor Influence on BehaviorGenetics and Neurodevelopmental Disorders

Cited by 8