Spiegelman, Bruce M.

Use of the Peroxisome Proliferator-Activated Receptor (PPAR) γ Ligand Troglitazone as Treatment for Refractory Breast Cancer: A Phase II Study

Burstein, H. J., Demetri, G. D., Mueller, E., Sarraf, P., Spiegelman, B. M., & Winer, E. P. (2003) · Breast Cancer Research and Treatment

Peroxisome Proliferator-Activated ReceptorsBreast Cancer Treatment Studies

Cited by 228

Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling

Bertholet, A. M., Kazak, L., Chouchani, E. T., Bogaczyńska, M. G., Paranjpe, I., Wainwright, G. L., Bétourné, A., Kajimura, S., Spiegelman, B. M., & Kirichok, Y. (2017) · Cell Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 225

Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators

Spiegelman, B. M. (2007) · Novartis Foundation Symposia

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 187

Appearance and disappearance of the mRNA signature characteristic of T reg cells in visceral adipose tissue: Age, diet, and PPARγ effects

Cipolletta, D., Cohen, P., Spiegelman, B. M., Benoist, C., & Mathis, D. (2015) · Proceedings of the National Academy of Sciences

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 186

Hypomorphic mutation of PGC-1β causes mitochondrial dysfunction and liver insulin resistance.

Vianna, C. R., Huntgeburth, M., Coppari, R., Choi, C. S., Lin, J., Krauss, S., Barbatelli, G., Tzameli, I., Kim, Y.-B., Cinti, S., et al. (2006) · Cell Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 181

γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis

Hu, B., Jin, C., Zeng, X., Resch, J. M., Jedrychowski, M. P., Yang, Z., Desai, B. N., Banks, A. S., Lowell, B. B., Mathis, D., et al. (2020) · Nature

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 180

NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection

Volakakis, N., Kadkhodaei, B., Joodmardi, E., Wallis, K., Panman, L., Silvaggi, J., Spiegelman, B. M., & Perlmann, T. (2010) · Proceedings of the National Academy of Sciences

Nuclear Receptors and SignalingNeuroscience and Neuropharmacology Research

Cited by 167

PPARδ Agonism Activates Fatty Acid Oxidation via PGC-1α but Does Not Increase Mitochondrial Gene Expression and Function

Kleiner, S., Nguyen-Tran, V., Baré, O., Huang, X., Spiegelman, B., & Wu, Z. (2009) · Journal of Biological Chemistry

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 143

Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α

Yoon, J. C., Xu, G., Deeney, J. T., Yang, S.-N., Rhee, J., Puigserver, P., Levens, A. R., Yang, R., Zhang, C.-Y., Lowell, B. B., et al. (2003) · Developmental Cell

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 143

Combined Training Enhances Skeletal Muscle Mitochondrial Oxidative Capacity Independent of Age

Irving, B. A., Lanza, I. R., Henderson, G. C., Rao, R. R., Spiegelman, B. M., & Nair, K. S. (2015) · The Journal of Clinical Endocrinology & Metabolism

Cardiovascular and exercise physiologyMitochondrial Function and Pathology

Cited by 139

Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin

Kam, T.-I., Park, H., Chou, S.-C., Van Vranken, J. G., Mittenbühler, M. J., Kim, H., A, M., Choi, Y. R., Biswas, D., Wang, J., et al. (2022) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 125

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

White, J. P., Wrann, C. D., Rao, R. R., Nair, S. K., Jedrychowski, M. P., You, J.-S., Martínez-Redondo, V., Gygi, S. P., Ruas, J. L., Hornberger, T. A., et al. (2014) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 123

Hormones, Metabolism and the Benefits of Exercise

Spiegelman, B. M. (2017) · Research and Perspectives in Endocrine Interactions

Exercise and Physiological ResponsesMetabolism, Diabetes, and Cancer

Cited by 44

Biosynthetic regulation of monobutyrin, an adipocyte-secreted lipid with angiogenic activity

Wilkison, W. O., Choy, L., & Spiegelman, B. M. (1991) · Journal of Biological Chemistry

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

Cited by 29