Pantopoulos, Kostas

Iron metabolism and toxicity

Papanikolaou, G., & Pantopoulos, K. (2005) · Toxicology and Applied Pharmacology

Iron Metabolism and DisordersTrace Elements in Health

Cited by 1,070

Regulation of cellular iron metabolism

Wang, J., & Pantopoulos, K. (2011) · Biochemical Journal

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 986

Mechanisms of mammalian iron homeostasis

Pantopoulos, K., Porwal, S. K., Tartakoff, A., & Devireddy, L. (2012) · Biochemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 598

Regulation of iron transport and the role of transferrin

Gkouvatsos, K., Papanikolaou, G., & Pantopoulos, K. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 518

Translational regulation via iron‐responsive elements by the nitric oxide/NO‐synthase pathway.

Weiss, G., Goossen, B., Doppler, W., Fuchs, D., Pantopoulos, K., Werner‐Felmayer, G., Wachter, H., & Hentze, M. W. (1993) · The EMBO Journal

Iron Metabolism and DisordersNitric Oxide and Endothelin Effects

Cited by 389

The IRP/IRE system in vivo: insights from mouse models

Wilkinson, N., & Pantopoulos, K. (2014) · Frontiers in Pharmacology

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 366

Oxidative Stress and Iron Homeostasis: Mechanistic and Health Aspects

Galaris, D., & Pantopoulos, K. (2008) · Critical Reviews in Clinical Laboratory Sciences

Iron Metabolism and DisordersTrace Elements in Health

Cited by 352

Nitric Oxide and Oxidative Stress (H2O2) Control Mammalian Iron Metabolism by Different Pathways

Pantopoulos, K., Weiss, G., & Hentze, M. W. (1996) · Molecular and Cellular Biology

Iron Metabolism and DisordersTrace Elements in Health

Cited by 195

Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing

Zimmer, M., Ebert, B. L., Neil, C., Brenner, K., Papaioannou, I., Melas, A., Tolliday, N., Lamb, J., Pantopoulos, K., Golub, T., et al. (2008) · Molecular Cell

Cancer, Hypoxia, and MetabolismRNA and protein synthesis mechanisms

Cited by 191

Pharmacological Targeting of the Hepcidin/Ferroportin Axis

Sebastiani, G., Wilkinson, N., & Pantopoulos, K. (2016) · Frontiers in Pharmacology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 127

Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts

Chen, G., Fillebeen, C., Wang, J., & Pantopoulos, K. (2006) · Carcinogenesis

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 55

Function of the hemochromatosis protein HFE: Lessons from animal models

Pantopoulos, K. (2008) · World Journal of Gastroenterology

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 49

Sustained Hydrogen Peroxide Induces Iron Uptake by Transferrin Receptor-1 Independent of the Iron Regulatory Protein/Iron-responsive Element Network

Andriopoulos, B., Hegedüsch, S., Mangin, J., Riedel, H.-D., Hebling, U., Wang, J., Pantopoulos, K., & Mueller, S. (2007) · Journal of Biological Chemistry

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 48

The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta2-microglobulin

WANG, J., CHEN, G., & PANTOPOULOS, K. (2003) · Biochemical Journal

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 28

A crosstalk between hepcidin and IRE/IRP pathways controls ferroportin expression and determines serum iron levels in mice

Charlebois, E., Fillebeen, C., Katsarou, A., Rabinovich, A., Wisniewski, K., Venkataramani, V., Michalke, B., Velentza, A., & Pantopoulos, K. (2022) · eLife

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 22

Alternative ferritin mRNA translation via internal initiation

Daba, A., Koromilas, A. E., & Pantopoulos, K. (2012) · RNA

RNA and protein synthesis mechanismsIron Metabolism and Disorders

Cited by 17