Lu, Timothy K.

Dispersing biofilms with engineered enzymatic bacteriophage

Lu, T. K., & Collins, J. J. (2007) · Proceedings of the National Academy of Sciences

Bacteriophages and microbial interactionsBacterial biofilms and quorum sensing

Cited by 895

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

Citorik, R. J., Mimee, M., & Lu, T. K. (2014) · Nature Biotechnology

CRISPR and Genetic EngineeringBacteriophages and microbial interactions

Cited by 808

An ingestible bacterial-electronic system to monitor gastrointestinal health

Mimee, M., Nadeau, P., Hayward, A., Carim, S., Flanagan, S., Jerger, L., Collins, J., McDonnell, S., Swartwout, R., Citorik, R. J., et al. (2018) · Science

Biosensors and Analytical Detectionbioluminescence and chemiluminescence research

Cited by 606

Synthetic circuits integrating logic and memory in living cells

Siuti, P., Yazbek, J., & Lu, T. K. (2013) · Nature Biotechnology

Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology

Cited by 531

Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota

Mimee, M., Tucker, A. C., Voigt, C. A., & Lu, T. K. (2015) · Cell Systems

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 387

Next-generation synthetic gene networks

Lu, T. K., Khalil, A. S., & Collins, J. J. (2009) · Nature Biotechnology

Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction

Cited by 365

Genomically encoded analog memory with precise in vivo DNA writing in living cell populations

Farzadfard, F., & Lu, T. K. (2014) · Science

Gene Regulatory Network AnalysisCRISPR and Genetic Engineering

Cited by 298

Permanent genetic memory with >1-byte capacity

Yang, L., Nielsen, A. A. K., Fernandez-Rodriguez, J., McClune, C. J., Laub, M. T., Lu, T. K., & Voigt, C. A. (2014) · Nature Methods

Gene Regulatory Network AnalysisCRISPR and Genetic Engineering

Cited by 243

Enhancing phage therapy through synthetic biology and genome engineering

Lenneman, B. R., Fernbach, J., Loessner, M. J., Lu, T. K., & Kilcher, S. (2021) · Current Opinion in Biotechnology

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 208

Magnetic Living Hydrogels for Intestinal Localization, Retention, and Diagnosis

Liu, X., Yang, Y., Inda, M. E., Lin, S., Wu, J., Kim, Y., Chen, X., Ma, D., Lu, T. K., & Zhao, X. (2021) · Advanced Functional Materials

Hydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems

Cited by 175

High-throughput 5’ UTR engineering for enhanced protein production in non-viral gene therapies

Cao, J., Novoa, E. M., Zhang, Z., Chen, W. C. W., Liu, D., Choi, G. C. G., Wong, A. S. L., Wehrspaun, C., Kellis, M., & Lu, T. K. (2021) · Nature Communications

Virus-based gene therapy researchRNA and protein synthesis mechanisms

Cited by 159

Single-Nucleotide-Resolution Computing and Memory in Living Cells

Farzadfard, F., Gharaei, N., Higashikuni, Y., Jung, G., Cao, J., & Lu, T. K. (2019) · Molecular Cell

Gene Regulatory Network AnalysisDNA and Biological Computing

Cited by 122

Emerging applications for DNA writers and molecular recorders

Farzadfard, F., & Lu, T. K. (2018) · Science

CRISPR and Genetic EngineeringGene Regulatory Network Analysis

Cited by 102

Deep generative models generate mRNA sequences with enhanced translation capacity and stability

Zhang, H., Liu, H., Xu, Y., Liu, Y., Wang, J., Qin, Y., Wang, H., Ma, L., Xun, Z., Lu, T. K., et al. (2024) · Science

RNA and protein synthesis mechanismsRNA Interference and Gene Delivery

Cited by 79