Zhang, Quan

Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion

Braun, M., Ramracheya, R., Bengtsson, M., Zhang, Q., Karanauskaite, J., Partridge, C., Johnson, P. R., & Rorsman, P. (2008) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 417

MicroRNA-7a regulates pancreatic β cell function

Latreille, M., Hausser, J., Stützer, I., Zhang, Q., Hastoy, B., Gargani, S., Kerr-Conte, J., Pattou, F., Zavolan, M., Esguerra, J. L. S., et al. (2014) · Journal of Clinical Investigation

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 281

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

Brereton, M. F., Iberl, M., Shimomura, K., Zhang, Q., Adriaenssens, A. E., Proks, P., Spiliotis, I. I., Dace, W., Mattis, K. K., Ramracheya, R., et al. (2014) · Nature Communications

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 259

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

De Marinis, Y. Z., Salehi, A., Ward, C. E., Zhang, Q., Abdulkader, F., Bengtsson, M., Braha, O., Braun, M., Ramracheya, R., Amisten, S., et al. (2010) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 257

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

Zhang, Q., Ramracheya, R., Lahmann, C., Tarasov, A., Bengtsson, M., Braha, O., Braun, M., Brereton, M., Collins, S., Galvanovskis, J., et al. (2013) · Cell Metabolism

Pancreatic function and diabetesIon channel regulation and function

Cited by 225

Regulation of calcium in pancreatic α- and β-cells in health and disease

Rorsman, P., Braun, M., & Zhang, Q. (2012) · Cell Calcium

Pancreatic function and diabetesIon channel regulation and function

Cited by 220

Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?

Brereton, M. F., Vergari, E., Zhang, Q., & Clark, A. (2015) · Journal of Histochemistry & Cytochemistry

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 206

Capacitance measurements of exocytosis in mouse pancreatic α‐, β‐ and δ‐cells within intact islets of Langerhans

Göpel, S., Zhang, Q., Eliasson, L., Ma, X., Galvanovskis, J., Kanno, T., Salehi, A., & Rorsman, P. (2004) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 160

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Vergari, E., Knudsen, J. G., Ramracheya, R., Salehi, A., Zhang, Q., Adam, J., Asterholm, I. W., Benrick, A., Briant, L. J. B., Chibalina, M. V., et al. (2019) · Nature Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 152

Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules

Hoppa, M. B., Collins, S., Ramracheya, R., Hodson, L., Amisten, S., Zhang, Q., Johnson, P., Ashcroft, F. M., & Rorsman, P. (2009) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 152

Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets

Ramracheya, R., Ward, C., Shigeto, M., Walker, J. N., Amisten, S., Zhang, Q., Johnson, P. R., Rorsman, P., & Braun, M. (2010) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 136

GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca 2+ channels

Ramracheya, R., Chapman, C., Chibalina, M., Dou, H., Miranda, C., González, A., Moritoh, Y., Shigeto, M., Zhang, Q., Braun, M., et al. (2018) · Physiological Reports

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 128

R-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion

Zhang, Q., Bengtsson, M., Partridge, C., Salehi, A., Braun, M., Cox, R., Eliasson, L., Johnson, P. R., Renström, E., Schneider, T., et al. (2007) · Nature Cell Biology

Pancreatic function and diabetesIon channel regulation and function

Cited by 110

Glucagon secretion from pancreatic α-cells

Briant, L., Salehi, A., Vergari, E., Zhang, Q., & Rorsman, P. (2016) · Upsala Journal of Medical Sciences

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 109

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans

Rorsman, P., Eliasson, L., Kanno, T., Zhang, Q., & Gopel, S. (2011) · Progress in Biophysics and Molecular Biology

Pancreatic function and diabetesIon channel regulation and function

Cited by 103

Synaptotagmin‐7 is a principal Ca2+ sensor for Ca2+‐induced glucagon exocytosis in pancreas

Gustavsson, N., Wei, S., Hoang, D. N., Lao, Y., Zhang, Q., Radda, G. K., Rorsman, P., Südhof, T. C., & Han, W. (2009) · The Journal of Physiology

Cellular transport and secretionPancreatic function and diabetes

Cited by 100

Na+ current properties in islet α‐ and β‐cells reflect cell‐specific Scn3a and Scn9a expression

Zhang, Q., Chibalina, M. V., Bengtsson, M., Groschner, L. N., Ramracheya, R., Rorsman, N. J. G., Leiss, V., Nassar, M. A., Welling, A., Gribble, F. M., et al. (2014) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 90

Cell coupling in mouse pancreatic β-cells measured in intact islets of Langerhans

Zhang, Q., Galvanovskis, J., Abdulkader, F., Partridge, C. J., Göpel, S. O., Eliasson, L., & Rorsman, P. (2008) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

Pancreatic function and diabetesConnexins and lens biology

Cited by 80

Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory Vesicles

Collins, S. C., Hoppa, M. B., Walker, J. N., Amisten, S., Abdulkader, F., Bengtsson, M., Fearnside, J., Ramracheya, R., Toye, A. A., Zhang, Q., et al. (2010) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 73

Functional identification of islet cell types by electrophysiological fingerprinting

Briant, L. J. B., Zhang, Q., Vergari, E., Kellard, J. A., Rodriguez, B., Ashcroft, F. M., & Rorsman, P. (2017) · Journal of The Royal Society Interface

Pancreatic function and diabetesNeural dynamics and brain function

Cited by 59

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta cells

Vergari, E., Denwood, G., Salehi, A., Zhang, Q., Adam, J., Alrifaiy, A., Wernstedt Asterholm, I., Benrick, A., Chibalina, M. V., Eliasson, L., et al. (2020) · Nature Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 43

Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes

Hill, T. G., Gao, R., Benrick, A., Kothegala, L., Rorsman, N., Santos, C., Acreman, S., Briant, L. J., Dou, H., Gandasi, N. R., et al. (2024) · Nature Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 37

GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion

Gandasi, N. R., Gao, R., Kothegala, L., Pearce, A., Santos, C., Acreman, S., Basco, D., Benrick, A., Chibalina, M. V., Clark, A., et al. (2024) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 31