Sorek, Rotem

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Dominissini, D., Moshitch-Moshkovitz, S., Schwartz, S., Salmon-Divon, M., Ungar, L., Osenberg, S., Cesarkas, K., Jacob-Hirsch, J., Amariglio, N., Kupiec, M., et al. (2012) · Nature

RNA modifications and cancerRNA regulation and disease

Cited by 4,884

CRISPR-mediated adaptive immune systems in bacteria and archaea

Sorek, R., Lawrence, C. M., & Wiedenheft, B. (2013) · Annual Review of Biochemistry

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 668

Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

Federici, S., Kredo-Russo, S., Valdés-Mas, R., Kviatcovsky, D., Weinstock, E., Matiuhin, Y., Silberberg, Y., Atarashi, K., Furuichi, M., Oka, A., et al. (2022) · Cell

Bacteriophages and microbial interactionsGut microbiota and health

Cited by 542

An expanded arsenal of immune systems that protect bacteria from phages

Millman, A., Melamed, S., Leavitt, A., Doron, S., Bernheim, A., Hör, J., Garb, J., Bechon, N., Brandis, A., Lopatina, A., et al. (2022) · Cell Host & Microbe

Bacteriophages and microbial interactionsBacterial Genetics and Biotechnology

Cited by 428

Discovery of phage determinants that confer sensitivity to bacterial immune systems

Stokar-Avihail, A., Fedorenko, T., Garb, J., Leavitt, A., Millman, A., Shulman, G., Wojtania, N., Melamed, S., Amitai, G., & Sorek, R. (2022) · Cell

Bacteriophages and microbial interactionsBacterial Genetics and Biotechnology

Cited by 195

Discovery of phage determinants that confer sensitivity to bacterial immune systems

Stokar-Avihail, A., Fedorenko, T., Hör, J., Garb, J., Leavitt, A., Millman, A., Shulman, G., Wojtania, N., Melamed, S., Amitai, G., et al. (2023) · Cell

Bacteriophages and microbial interactionsBacterial Genetics and Biotechnology

Cited by 176

Phages overcome bacterial immunity via diverse anti-defense proteins

Yirmiya, E., Leavitt, A., Lu, A., Avraham, C., Osterman, I., Garb, J., Antine, S. P., Mooney, S. E., Hobbs, S. J., Kranzusch, P. J., et al. (2023) · Nature

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 144

Sir2-domain associated short prokaryotic Argonautes provide defence against invading mobile genetic elements through NAD+ depletion

Zaremba, M., Dakineviciene, D., Golovinas, E., Stankunas, E., Lopatina, A., Sorek, R., Manakova, E., Ruksenaite, A., Silanskas, A., Ašmontas, S., et al. (2022) · Nature Microbiology

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 126

Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD + depletion

Zaremba, M., Dakineviciene, D., Golovinas, E., Zagorskaitė, E., Stankunas, E., Lopatina, A., Sorek, R., Manakova, E., Ruksenaite, A., Silanskas, A., et al. (2021) · Nature Microbiology

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 126

Structural basis of Gabija anti-phage defence and viral immune evasion

Antine, S. P., Johnson, A. G., Mooney, S. E., Leavitt, A., Mayer, M. L., Yirmiya, E., Amitai, G., Sorek, R., & Kranzusch, P. J. (2024) · Nature

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 125

Structural basis of Gabija anti-phage defense and viral immune evasion

Antine, S. P., Johnson, A. G., Mooney, S. E., Leavitt, A., Mayer, M. L., Yirmiya, E., Amitai, G., Sorek, R., & Kranzusch, P. J. (2023) · Nature

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 125

A conserved family of immune effectors cleaves cellular ATP upon viral infection

Rousset, F., Yirmiya, E., Nesher, S., Brandis, A., Mehlman, T., Itkin, M., Malitsky, S., Millman, A., Melamed, S., & Sorek, R. (2023) · Cell

Bacteriophages and microbial interactionsInvertebrate Immune Response Mechanisms

Cited by 93

Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly

Hör, J., Wolf, S. G., & Sorek, R. (2023) · Nature

Bacteriophages and microbial interactionsInvertebrate Immune Response Mechanisms

Cited by 46

Diversification of molecular pattern recognition in bacterial NLR-like proteins

Béchon, N., Tal, N., Stokar-Avihail, A., Melamed, S., Amitai, G., & Sorek, R. (2024) · Nature Communications

Bacteriophages and microbial interactionsInvertebrate Immune Response Mechanisms

Cited by 23