Pellman, David

DNA breaks and chromosome pulverization from errors in mitosis

Crasta, K., Ganem, N. J., Dagher, R., Lantermann, A. B., Ivanova, E. V., Pan, Y., Nezi, L., Protopopov, A., Chowdhury, D., & Pellman, D. (2012) · Nature

Microtubule and mitosis dynamicsDNA Repair Mechanisms

Cited by 1,227

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

Fujiwara, T., Bandi, M., Nitta, M., Ivanova, E. V., Bronson, R. T., & Pellman, D. (2005) · Nature

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 1,067

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Cortés-Ciriano, I., Lee, J. J.-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C.-Z., Pellman, D. S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 712

Tetraploidy, aneuploidy and cancer

Ganem, N. J., Storchova, Z., & Pellman, D. (2007) · Current Opinion in Genetics & Development

Microtubule and mitosis dynamicsChromosomal and Genetic Variations

Cited by 668

Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing

Leibowitz, M. L., Papathanasiou, S., Doerfler, P. A., Blaine, L. J., Sun, L., Yao, Y., Zhang, C.-Z., Weiss, M. J., & Pellman, D. (2021) · Nature Genetics

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 583

Mechanisms generating cancer genome complexity from a single cell division error

Umbreit, N. T., Zhang, C.-Z., Lynch, L. D., Blaine, L. J., Cheng, A. M., Tourdot, R., Sun, L., Almubarak, H. F., Judge, K., Mitchell, T. J., et al. (2020) · Science

Genomic variations and chromosomal abnormalitiesDNA Repair Mechanisms

Cited by 439

Nuclear envelope assembly defects link mitotic errors to chromothripsis

Liu, S., Kwon, M., Mannino, M., Yang, N., Renda, F., Khodjakov, A., & Pellman, D. (2018) · Nature

Nuclear Structure and FunctionMicrotubule and mitosis dynamics

Cited by 314

Cancer Genomes Evolve by Pulverizing Single Chromosomes

Meyerson, M., & Pellman, D. (2011) · Cell

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 115