Lopera, Francisco

Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease

Sepulveda‐Falla, D., Matschke, J., Bernreuther, C., Hagel, C., Puig, B., Villegas, A., Garcia, G., Zea, J., Gomez‐Mancilla, B., Ferrer, I., et al. (2011) · Brain Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Memory binding and white matter integrity in familial Alzheimer’s disease

Parra, M. A., Saarimäki, H., Bastin, M. E., Londoño, A. C., Pettit, L., Lopera, F., Della Sala, S., & Abrahams, S. (2015) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Phenotypic Profile of Early-Onset Familial Alzheimer's Disease Caused by Presenilin-1 E280A Mutation

Sepulveda-Falla, D., Glatzel, M., & Lopera, F. (2012) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease

Lalli, M. A., Bettcher, B. M., Arcila, M. L., Garcia, G., Guzman, C., Madrigal, L., Ramirez, L., Acosta-Uribe, J., Baena, A., Wojta, K. J., et al. (2015) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease

Quiroz, Y. T., Aguillon, D., Aguirre-Acevedo, D. C., Vasquez, D., Zuluaga, Y., Baena, A. Y., Madrigal, L., Hincapié, L., Sanchez, J. S., Langella, S., et al. (2024) · New England Journal of Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Origin of the PSEN1 E280A mutation causing early‐onset Alzheimer's disease

Lalli, M. A., Cox, H. C., Arcila, M. L., Cadavid, L., Moreno, S., Garcia, G., Madrigal, L., Reiman, E. M., Arcos‐Burgos, M., Bedoya, G., et al. (2014) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsForensic and Genetic Research

Cited by 60

Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer’s disease: findings from the Colombia-Boston (COLBOS) biomarker study

Sanchez, J. S., Hanseeuw, B. J., Lopera, F., Sperling, R. A., Baena, A., Bocanegra, Y., Aguillon, D., Guzmán-Vélez, E., Pardilla-Delgado, E., Ramirez-Gomez, L., et al. (2021) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer's Disease: A Comprehensive Review of the Colombian Kindred

Fuller, J. T., Cronin-Golomb, A., Gatchel, J. R., Norton, D. J., Guzmán-Vélez, E., Jacobs, H. I. L., Hanseeuw, B., Pardilla-Delgado, E., Artola, A., Baena, A., et al. (2019) · The Journal of Prevention of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 57

A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD

Jain, M., Vélez, J. I., Acosta, M. T., Palacio, L. G., Balog, J., Roessler, E., Pineda, D., Londoño, A. C., Palacio, J. D., Arbelaez, A., et al. (2012) · Molecular Psychiatry

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

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Educational disparities in brain health and dementia across Latin America and the United States

Gonzalez‐Gomez, R., Legaz, A., Moguilner, S., Cruzat, J., Hernández, H., Baez, S., Cocchi, R., Coronel‐Olivero, C., Medel, V., Tagliazuchi, E., et al. (2024) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchCognitive Abilities and Testing

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Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): study design and harmonization

Crivelli, L., Calandri, I. L., Suemoto, C. K., Salinas, R. M., Velilla, L. M., Yassuda, M. S., Caramelli, P., Lopera, F., Nitrini, R., Sevlever, G. E., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchCognitive Abilities and Testing

Cited by 55

A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease

Sepulveda-Falla, D., Chavez-Gutierrez, L., Portelius, E., Vélez, J. I., Dujardin, S., Barrera-Ocampo, A., Dinkel, F., Hagel, C., Puig, B., Mastronardi, C., et al. (2021) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Plasma p‐tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease

Aguillon, D., Langella, S., Chen, Y., Sanchez, J. S., Su, Y., Vila‐Castelar, C., Vasquez, D., Zetterberg, H., Hansson, O., Dage, J. L., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation

Marino, C., Perez‐Corredor, P., O'Hare, M., Heuer, A., Chmielewska, N., Gordon, H., Chandrahas, A. S., Gonzalez‐Buendia, L., Delgado‐Tirado, S., Doan, T. H., et al. (2024) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease

Vélez, J. I., Chandrasekharappa, S. C., Henao, E., Martinez, A. F., Harper, U., Jones, M., Solomon, B. D., Lopez, L., Garcia, G., Aguirre-Acevedo, D. C., et al. (2013) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease

Levin, J., Vöglein, J., Quiroz, Y. T., Bateman, R. J., Ghisays, V., Lopera, F., McDade, E., Reiman, E., Tariot, P. N., & Morris, J. C. (2022) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer’s Disease Patient Astrocytes Impair Neuroglial and Vascular Components

González-Molina, L. A., Villar-Vesga, J., Henao-Restrepo, J., Villegas, A., Lopera, F., Cardona-Gómez, G. P., & Posada-Duque, R. (2021) · Frontiers in Aging Neuroscience

Extracellular vesicles in diseaseAlzheimer's disease research and treatments

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Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer’s disease

Sun, G. G., Wang, C., Mazzarino, R. C., Perez-Corredor, P. A., Davtyan, H., Blurton-Jones, M., Lopera, F., Arboleda-Velasquez, J. F., & Shi, Y. (2024) · Cell Reports

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Structural inequality linked to brain volume and network dynamics in aging and dementia across the Americas

Legaz, A., Altschuler, F., Gonzalez-Gomez, R., Hernández, H., Baez, S., Migeot, J., Fittipaldi, S., Medel, V., Maito, M. A., Godoy, M. E., et al. (2024) · Nature Aging

Dementia and Cognitive Impairment ResearchHealth disparities and outcomes

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The Nairobi Declaration—reducing the burden of dementia in low- and middle-income countries (LMICs): declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs

Maestre, G., Carrillo, M., Kalaria, R., Acosta, D., Adams, L., Adoukonou, T., Akinwande, K., Akinyemi, J., Akinyemi, R., Akpa, O., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchMental Health Treatment and Access

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Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer’s disease

Langella, S., Barksdale, N. G., Vasquez, D., Aguillon, D., Chen, Y., Su, Y., Acosta-Baena, N., Acosta-Uribe, J., Baena, A. Y., Garcia-Ospina, G., et al. (2023) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia

Llibre-Guerra, J. J., Fernandez, M. V., Joseph-Mathurin, N., Bian, S., Carter, K., Li, Y., Aschenbrenner, A. J., Pottier, C., Sigurdson, W., McDade, E., et al. (2025) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Normative data stratified by age and education for a Spanish neuropsychological test battery: Results from the Colombian Alzheimer’s prevention initiative registry

Torres, V. L., Vila-Castelar, C., Bocanegra, Y., Baena, A., Guzmán-Vélez, E., Aguirre-Acevedo, D. C., Tirado, V., Munoz, C., Henao, E., Moreno, S., et al. (2021) · Applied Neuropsychology: Adult

Dementia and Cognitive Impairment ResearchHistorical and Modern Theater Studies

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APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases

Perez-Corredor, P., Vanderleest, T. E., Vacano, G. N., Sanchez, J. S., Villalba-Moreno, N. D., Marino, C., Krasemann, S., Mendivil-Perez, M. A., Aguillón, D., Jiménez-Del-Río, M., et al. (2024) · Frontiers in Molecular Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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