Reich, Daniel S.

Multiple sclerosis

Reich, D. S., Lucchinetti, C. F., & Calabresi, P. A. (2018) · New England Journal of Medicine

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 2,491

MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines

Filippi, M., Rocca, M. A., Ciccarelli, O., De Stefano, N., Evangelou, N., Kappos, L., Rovira, A., Sastre-Garriga, J., Tintorè, M., Frederiksen, J. L., et al. (2016) · The Lancet Neurology

Multiple Sclerosis Research StudiesClinical Reasoning and Diagnostic Skills

Cited by 880

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

Absinta, M., Maric, D., Gharagozloo, M., Garton, T., Smith, M. D., Jin, J., Fitzgerald, K. C., Song, A., Liu, P., Lin, J.-P., et al. (2021) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 768

Multiple sclerosis progression: time for a new mechanism-driven framework

Kuhlmann, T., Moccia, M., Coetzee, T., Cohen, J. A., Correale, J., Graves, J., Marrie, R. A., Montalban, X., Yong, V. W., Thompson, A. J., et al. (2023) · The Lancet Neurology

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 667

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI.

Absinta, M., Ha, S.-K., Nair, G., Sati, P., Luciano, N. J., Palisoc, M., Louveau, A., Zaghloul, K. A., Pittaluga, S., Kipnis, J., et al. (2017) · eLife

Lymphatic System and DiseasesCerebrospinal fluid and hydrocephalus

Cited by 643

Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria

Montalban, X., Lebrun-Frénay, C., Oh, J., Arrambide, G., Moccia, M., Pia Amato, M., Amezcua, L., Banwell, B., Bar-Or, A., Barkhof, F., et al. (2025) · The Lancet Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 551

Association of Chronic Active Multiple Sclerosis Lesions With Disability In Vivo

Absinta, M., Sati, P., Masuzzo, F., Nair, G., Sethi, V., Kolb, H., Ohayon, J., Wu, T., Cortese, I. C. M., & Reich, D. S. (2019) · JAMA Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 534

Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

Werneburg, S., Jung, J., Kunjamma, R. B., Ha, S.-K., Luciano, N. J., Willis, C. M., Gao, G., Biscola, N. P., Havton, L. A., Crocker, S. J., et al. (2020) · Immunity

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 440

Revised recommendations of the Consortium of MS Centers task force for a standardized MRI protocol and clinical guidelines for the diagnosis and follow-up of multiple sclerosis

Traboulsee, A., Simon, J. H., Stone, L., Fisher, E., Jones, D. E., Malhotra, A., Newsome, S. D., Oh, J., Reich, D. S., Richert, N., et al. (2016) · American Journal of Neuroradiology

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 340

Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions

Absinta, M., Sati, P., Schindler, M., Leibovitch, E. C., Ohayon, J., Wu, T., Meani, A., Filippi, M., Jacobson, S., Cortese, I. C. M., et al. (2016) · Journal of Clinical Investigation

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 327

Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis

Absinta, M., Vuolo, L., Rao, A., Nair, G., Sati, P., Cortese, I. C. M., Ohayon, J., Fenton, K., Reyes-Mantilla, M. I., Maric, D., et al. (2015) · Neurology

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 296

Identification of direct connections between the dura and the brain

Smyth, L. C. D., Xu, D., Okar, S. V., Dykstra, T., Rustenhoven, J., Papadopoulos, Z., Bhasiin, K., Kim, M. W., Drieu, A., Mamuladze, T., et al. (2024) · Nature

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 264

Safety and efficacy of tolebrutinib, an oral brain-penetrant BTK inhibitor, in relapsing multiple sclerosis: A phase 2b, randomised, double-blind, placebo-controlled trial

Reich, D. S., Arnold, D. L., Vermersch, P., Bar-Or, A., Fox, R. J., Matta, A., Turner, T., Wallström, E., Zhang, X., Mareš, M., et al. (2021) · The Lancet Neurology

Multiple Sclerosis Research StudiesChronic Lymphocytic Leukemia Research

Cited by 204

Evolution of the blood–brain barrier in newly forming multiple sclerosis lesions

Gaitán, M. I., Shea, C. D., Evangelou, I. E., Stone, R. D., Fenton, K. M., Bielekova, B., Massacesi, L., & Reich, D. S. (2011) · Annals of Neurology

Multiple Sclerosis Research StudiesBarrier Structure and Function Studies

Cited by 174

Tolebrutinib in Nonrelapsing Secondary Progressive Multiple Sclerosis

Fox, R. J., Bar-Or, A., Traboulsee, A., Oreja-Guevara, C., Giovannoni, G., Vermersch, P., Syed, S., Li, Y., Vargas, W. S., Turner, T. J., et al. (2025) · New England Journal of Medicine

Multiple Sclerosis Research StudiesChronic Lymphocytic Leukemia Research

Cited by 146

2024 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI for the diagnosis of multiple sclerosis

Barkhof, F., Reich, D. S., Oh, J., Rocca, M. A., Li, D. K. B., Sati, P., Azevedo, C. J., Bagnato, F., Calabresi, P. A., Ciccarelli, O., et al. (2025) · The Lancet Neurology

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 113

The formation of inflammatory demyelinated lesions in cerebral white matter

Maggi, P., Macri, S. M. C., Gaitán, M. I., Leibovitch, E., Wholer, J. E., Knight, H. L., Ellis, M., Wu, T., Silva, A. C., Massacesi, L., et al. (2014) · Annals of Neurology

Multiple Sclerosis Research StudiesBarrier Structure and Function Studies

Cited by 110

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

Schäffner, E., Bosch-Queralt, M., Edgar, J. M., Lehning, M., Strauß, J., Fleischer, N., Kungl, T., Wieghofer, P., Berghoff, S. A., Reinert, T., et al. (2023) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 101

B cell depletion therapy does not resolve chronic active multiple sclerosis lesions

Maggi, P., Bulcke, C. V., Pedrini, E., Bugli, C., Sellimi, A., Wynen, M., Stölting, A., Mullins, W. A., Kalaitzidis, G., Lolli, V., et al. (2023) · eBioMedicine

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 92

Paramagnetic rim lesions in multiple sclerosis: Comparison of visualization at 1.5-T and 3-T MRI

Hemond, C. C., Reich, D. S., & Dundamadappa, S. K. (2022) · American Journal of Roentgenology

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 66

Central Vein Sign, Cortical Lesions, and Paramagnetic Rim Lesions for the Diagnostic and Prognostic Workup of Multiple Sclerosis

Borrelli, S., Martire, M. S., Stölting, A., Vanden Bulcke, C., Pedrini, E., Guisset, F., Bugli, C., Yildiz, H., Pothen, L., Elands, S., et al. (2024) · Neurology Neuroimmunology & Neuroinflammation

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 61

Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues

La Rosa, F., Wynen, M., Al-Louzi, O., Beck, E. S., Huelnhagen, T., Maggi, P., Thiran, J.-P., Kober, T., Shinohara, R. T., Sati, P., et al. (2022) · NeuroImage: Clinical

Multiple Sclerosis Research StudiesMedical Image Segmentation Techniques

Cited by 58

Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine

Summers, R. A., Fagiani, F., Rowitch, D. H., Absinta, M., & Reich, D. S. (2024) · Trends in Immunology

Pluripotent Stem Cells ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 39

4D marmoset brain map reveals MRI and molecular signatures for onset of multiple sclerosis–like lesions

Lin, J.-P., Brake, A., Donadieu, M., Lee, A., Smith, G., Hu, K., Nair, G., Kawaguchi, R., Sati, P., Geschwind, D. H., et al. (2025) · Science

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 35