Menche, Jörg

Uncovering disease-disease relationships through the incomplete interactome

Menche, J., Sharma, A., Kitsak, M., Ghiassian, S. D., Vidal, M., Loscalzo, J., & Barabási, A.-L. (2015) · Science

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 1,546

Canonical genetic signatures of the adult human brain

Hawrylycz, M., Miller, J. A., Menon, V., Feng, D., Dolbeare, T., Guillozet-Bongaarts, A. L., Jegga, A. G., Aronow, B. J., Lee, C.-K., Bernard, A., et al. (2015) · Nature Neuroscience

Functional Brain Connectivity StudiesSingle-cell and spatial transcriptomics

Cited by 663

Network-based in silico drug efficacy screening

Guney, E., Menche, J., Vidal, M., & Barábasi, A.-L. (2016) · Nature Communications

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 625

Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation

Mayor-Ruiz, C., Jaeger, M. G., Bauer, S., Brand, M., Sin, C., Hanzl, A., Mueller, A. C., Menche, J., & Winter, G. E. (2019) · Molecular Cell

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 119

Network analysis reveals rare disease signatures across multiple levels of biological organization

Buphamalai, P., Kokotovic, T., Nagy, V., & Menche, J. (2021) · Nature Communications

Bioinformatics and Genomic NetworksGenomics and Rare Diseases

Cited by 95

Large neutral amino acid levels tune perinatal neuronal excitability and survival

Knaus, L. S., Basilico, B., Malzl, D., Gerykova Bujalkova, M., Smogavec, M., Schwarz, L. A., Gorkiewicz, S., Amberg, N., Pauler, F. M., Knittl-Frank, C., et al. (2023) · Cell

Amino Acid Enzymes and MetabolismMetabolomics and Mass Spectrometry Studies

Cited by 70

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

Salzer, E., Zoghi, S., Kiss, M. G., Kage, F., Rashkova, C., Stahnke, S., Haimel, M., Platzer, R., Caldera, M., Ardy, R. C., et al. (2020) · Science Immunology

T-cell and B-cell ImmunologySystemic Lupus Erythematosus Research

Cited by 48