Caughey, George H.

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

Coussens, L. M., Raymond, W. W., Bergers, G., Laig-Webster, M., Behrendtsen, O., Werb, Z., Caughey, G. H., & Hanahan, D. (1999) · Genes & Development

Angiogenesis and VEGF in CancerMast cells and histamine

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Mast cell tryptases and chymases in inflammation and host defense.

Caughey, G. H. (2007) · Immunological Reviews

Mast cells and histamineProtease and Inhibitor Mechanisms

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Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

Lyons, J. J., Yu, X., Hughes, J. D., Le, Q. T., Jamil, A., Bai, Y., Ho, N., Zhao, M., Liu, Y., O'Connell, M. P., et al. (2016) · Nature Genetics

Mast cells and histamineGastrointestinal motility and disorders

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Mast cell tryptase is a mitogen for cultured fibroblasts

Ruoss, S. J., Hartmann, T., & Caughey, G. H. (1991) · Journal of Clinical Investigation

Mast cells and histamineProtease and Inhibitor Mechanisms

Cited by 390

Tryptase genetics and anaphylaxis

Caughey, G. H. (2006) · Journal of Allergy and Clinical Immunology

Mast cells and histamineFood Allergy and Anaphylaxis Research

Cited by 150

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3

Pallaoro, M., Fejzo, M. S., Shayesteh, L., Blount, J. L., & Caughey, G. H. (1999) · Journal of Biological Chemistry

Mast cells and histamineAsthma and respiratory diseases

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Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase.

Fang, K. C., Raymond, W. W., Lazarus, S. C., & Caughey, G. H. (1996) · Journal of Clinical Investigation

Protease and Inhibitor MechanismsMast cells and histamine

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Clinical relevance of inherited genetic differences in human tryptases

Glover, S. C., Carter, M. C., Korošec, P., Bonadonna, P., Schwartz, L. B., Milner, J. D., Caughey, G. H., Metcalfe, D. D., & Lyons, J. J. (2021) · Annals of Allergy, Asthma & Immunology

Mast cells and histamineFood Allergy and Anaphylaxis Research

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Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms

Chovanec, J., Tunc, I., Hughes, J., Halstead, J., Mateja, A., Liu, Y., O’Connell, M. P., Kim, J., Park, Y. H., Wang, Q., et al. (2023) · Blood Advances

Mast cells and histamineGenomics and Rare Diseases

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Protease-Activated Receptor 2, Dipeptidyl Peptidase I, and Proteases Mediate Clostridium difficile Toxin A Enteritis

Cottrell, G. S., Amadesi, S., Pikios, S., Camerer, E., Willardsen, J. A., Murphy, B. R., Caughey, G. H., Wolters, P. J., Coughlin, S. R., Peterson, A., et al. (2007) · Gastroenterology

Clostridium difficile and Clostridium perfringens researchBlood Coagulation and Thrombosis Mechanisms

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