Verhaagen, Joost

Alteration of the microRNA network during the progression of Alzheimer's disease

Lau, P., Bossers, K., Janky, R., Salta, E., Frigerio, C. S., Barbash, S., Rothman, R., Sierksma, A. S. R., Thathiah, A., Greenberg, D., et al. (2013) · EMBO Molecular Medicine

MicroRNA in disease regulationAlzheimer's disease research and treatments

Cited by 474

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression

Eisch, A. J., Bolaños, C. A., de Wit, J., Simonak, R. D., Pudiak, C. M., Barrot, M., Verhaagen, J., & Nestler, E. J. (2003) · Biological Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 420

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

Bossers, K., Wirz, K. T. S., Meerhoff, G. F., Essing, A. H. W., van Dongen, J. W., Houba, P., Kruse, C. G., Verhaagen, J., & Swaab, D. F. (2010) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 230

Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains

Dick, G., Tan, C. L., Alves, J. N., Ehlert, E. M. E., Miller, G. M., Hsieh-Wilson, L. C., Sugahara, K., Oosterhof, A., van Kuppevelt, T. H., Verhaagen, J., et al. (2013) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchAxon Guidance and Neuronal Signaling

Cited by 160

Semaphorin 3A displays a punctate distribution on the surface of neuronal cells and interacts with proteoglycans in the extracellular matrix

De Wit, J., De Winter, F., Klooster, J., & Verhaagen, J. (2005) · Molecular and Cellular Neuroscience

Axon Guidance and Neuronal SignalingNerve injury and regeneration

Cited by 154

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

Hellström, M., Ruitenberg, M. J., Pollett, M. A., Ehlert, E. M. E., Twisk, J., Verhaagen, J., & Harvey, A. R. (2009) · Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 142

Semaphorins in Adult Nervous System Plasticity and Disease

Carulli, D., de Winter, F., & Verhaagen, J. (2021) · Frontiers in Synaptic Neuroscience

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 137

Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters

Nieuwenhuis, B., Haenzi, B., Hilton, S., Carnicer-Lombarte, A., Hobo, B., Verhaagen, J., & Fawcett, J. W. (2021) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 114

Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: A comparison with lentiviral vectors

Harvey, A. R., Kamphuis, W., Eggers, R., Symons, N. A., Blits, B., Niclou, S., Boer, G. J., & Verhaagen, J. (2002) · Molecular and Cellular Neuroscience

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 114

Cerebellar plasticity and associative memories are controlled by perineuronal nets

Carulli, D., Broersen, R., de Winter, F., Muir, E. M., Mešković, M., de Waal, M., de Vries, S., Boele, H.-J., Canto, C. B., De Zeeuw, C. I., et al. (2020) · Proceedings of the National Academy of Sciences

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 110

The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity

de Winter, F., Kwok, J. C. F., Fawcett, J. W., Vo, T. T., Carulli, D., & Verhaagen, J. (2016) · Neural Plasticity

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 84

A perspective on the role of class III semaphorin signaling in central nervous system trauma

Mecollari, V., Nieuwenhuis, B., & Verhaagen, J. (2014) · Frontiers in Cellular Neuroscience

Axon Guidance and Neuronal SignalingNerve injury and regeneration

Cited by 79

Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

Yang, S., Gigout, S., Molinaro, A., Naito-Matsui, Y., Hilton, S., Foscarin, S., Nieuwenhuis, B., Tan, C. L., Verhaagen, J., Pizzorusso, T., et al. (2021) · Molecular Psychiatry

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 70

Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model

Wirz, K. T. S., Bossers, K., Stargardt, A., Kamphuis, W., Swaab, D. F., Hol, E. M., & Verhaagen, J. (2013) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 65

GFAP-Driven GFP Expression in Activated Mouse Müller Glial Cells Aligning Retinal Blood Vessels Following Intravitreal Injection of AAV2/6 Vectors

Aartsen, W. M., van Cleef, K. W. R., Pellissier, L. P., Hoek, R. M., Vos, R. M., Blits, B., Ehlert, E. M. E., Balaggan, K. S., Ali, R. R., Verhaagen, J., et al. (2010) · PLoS ONE

Retinal Development and DisordersVirus-based gene therapy research

Cited by 41

Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex

Boggio, E. M., Ehlert, E. M., Lupori, L., Moloney, E. B., De Winter, F., Vander Kooi, C. W., Baroncelli, L., Mecollari, V., Blits, B., Fawcett, J. W., et al. (2019) · Molecular Neurobiology

Axon Guidance and Neuronal SignalingVisual perception and processing mechanisms

Cited by 41

A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons

Fagoe, N. D., Eggers, R., Verhaagen, J., & Mason, M. R. J. (2014) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 27

Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis

Chen, J. Q. A., McNamara, N. B., Engelenburg, H. J., Jongejan, A., Wever, D. D., Hopman, K., van Rixel, E., Nijhuis, P. J. H., de Winter, F., Moerland, P. D., et al. (2025) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 17

microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer’s disease patients

Penning, A., Snoeck, S., Ormaechea, O. R., Ayyildiz, D., Polzer, O., Buitrago-Arango, M., Capobianco, R., de Winter, F., Balusu, S., Verhaagen, J., et al. (2026) · Acta Neuropathologica Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 6