Willis, Anne E.

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

Moreno, J. A., Halliday, M., Molloy, C., Radford, H., Verity, N., Axten, J. M., Ortori, C. A., Willis, A. E., Fischer, P. M., Barrett, D. A., et al. (2013) · Science Translational Medicine

Prion Diseases and Protein MisfoldingEndoplasmic Reticulum Stress and Disease

Cited by 589

The implications of structured 5′ untranslated regions on translation and disease

Pickering, B. M., & Willis, A. E. (2005) · Seminars in Cell & Developmental Biology

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 339

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

Sawicka, K., Bushell, M., Spriggs, K. A., & Willis, A. E. (2008) · Biochemical Society Transactions

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 332

Translational Repression and eIF4A2 Activity Are Critical for MicroRNA-Mediated Gene Regulation

Meijer, H. A., Kong, Y. W., Lu, W. T., Wilczynska, A., Spriggs, R. V., Robinson, S. W., Godfrey, J. D., Willis, A. E., & Bushell, M. (2013) · Science

MicroRNA in disease regulationRNA Research and Splicing

Cited by 326

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER

Hall, B. S., Hill, K., McKenna, M., Ogbechi, J., High, S., Willis, A. E., & Simmonds, R. E. (2014) · PLoS Pathogens

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

Cited by 162

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes

Ferland-McCollough, D., Fernandez-Twinn, D. S., Cannell, I. G., David, H., Warner, M., Vaag, A. A., Bork-Jensen, J., Brøns, C., Gant, T. W., Willis, A. E., et al. (2012) · Cell Death & Differentiation

Birth, Development, and HealthMicroRNA in disease regulation

Cited by 149

MNK Inhibition Sensitizes KRAS -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression

Knight, J. R. P., Alexandrou, C., Skalka, G. L., Vlahov, N., Pennel, K., Officer, L., Teodosio, A., Kanellos, G., Gay, D. M., May-Wilson, S., et al. (2021) · Cancer Discovery

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 96

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

Roobol, A., Roobol, J., Bastide, A., Knight, J. R. P., Willis, A. E., & Smales, C. M. (2015) · Biochemical Journal

Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms

Cited by 50

Interrogation of RNA-protein interaction dynamics in bacterial growth

Monti, M., Herman, R., Mancini, L., Capitanchik, C., Davey, K., Dawson, C. S., Ule, J., Thomas, G. H., Willis, A. E., Lilley, K. S., et al. (2024) · Molecular Systems Biology

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 16

Interrogation of RNA-protein interaction dynamics in bacterial growth

Monti, M., Herman, R., Davey, K., Dawson, C. S., Ule, J., Thomas, G. H., Willis, A. E., Lilley, K. S., & Villanueva, E. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 4