Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

The scanning model for translation: an update.

Kozak, M. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.2.229 · Cited by 3,485 · see citing works

The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Makeyev, E. V., Zhang, J., Carrasco, M. A., & Maniatis, T. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.07.015 · Cited by 1,395 · see citing works

Translational control of gene expression

Hannig, E. M. (2001) · BioEssays · doi:10.1002/bies.1108 · Cited by 1,195 · see citing works

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Boutz, P. L., Stoilov, P., Li, Q., Lin, C.-H., Chawla, G., Ostrow, K., Shiue, L., Ares, M., & Black, D. L. (2007) · Genes & Development · doi:10.1101/gad.1558107 · Cited by 577 · see citing works

Structure of PTB Bound to RNA: Specific Binding and Implications for Splicing Regulation

Oberstrass, F. C., Auweter, S., Erat, M. C., Hargous, Y., Henning, A., Wenter, P., Reymond, L., Amir-Ahmady, B., Pitsch, S., Black, D. L., et al. (2005) · Science · doi:10.1126/science.1114066 · Cited by 464 · see citing works

Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein.Preprint

Jang, S. K., & Wimmer, E. (1990) · Genes & Development · doi:10.1101/gad.4.9.1560 · Cited by 421 · see citing works

Autoregulation of Polypyrimidine Tract Binding Protein by Alternative Splicing Leading to Nonsense-Mediated Decay

Wollerton, M., Gooding, C., Wagner, E. J., García-Blanco, M. A., & Smith, C. W. J. (2004) · Molecular Cell · doi:10.1016/s1097-2765(03)00502-1 · Cited by 409 · see citing works

Regulation of Fas Alternative Splicing by Antagonistic Effects of TIA-1 and PTB on Exon Definition

Izquierdo, J. M., Oró, N. M., Bonnal, S., Martínez, C., Castelo, R., Guigó, R., Bilbao, D., & Valcárcel, J. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.06.015 · Cited by 364 · see citing works

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.Preprint

García-Blanco, M. A., Jamison, S. F., & Sharp, P. A. (1989) · Genes & Development · doi:10.1101/gad.3.12a.1874 · Cited by 346 · see citing works

Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants.

Gromeier, M., Alexander, L., & Wimmer, E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.6.2370 · Cited by 330 · see citing works

Crossregulation and Functional Redundancy between the Splicing Regulator PTB and Its Paralogs nPTB and ROD1

Spellman, R., Llorian, M., & Smith, C. W. J. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.06.016 · Cited by 313 · see citing works

Cooperative Assembly of an hnRNP Complex Induced by a Tissue-Specific Homolog of Polypyrimidine Tract Binding Protein

Markovtsov, V. V., Nikolic, J. M., Goldman, J. A., Turck, C. W., Chou, M., & Black, D. L. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.20.7463-7479.2000 · Cited by 311 · see citing works

hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

Ghetti, A., Piñol-Roma, S., Michael, W. M., Morandi, C., & Dreyfuss, G. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.14.3671 · Cited by 311 · see citing works

A cell cycle-dependent protein serves as a template-specific translation initiation factorPreprint

Pilipenko, E. V., Pestova, T. V., KOLUPAEVA, V. G., Khitrina, E. V., Poperechnaya, A. N., Agol, V. I., & Hellen, C. U. T. (2000) · Genes & Development · doi:10.1101/gad.14.16.2028 · Cited by 293 · see citing works

Re‐programming of translation following cell stress allows IRES‐mediated translation to predominate

Spriggs, K. A., Stoneley, M., Bushell, M., & Willis, A. E. (2007) · Biology of the Cell · doi:10.1042/bc20070098 · Cited by 292 · see citing works

The Apaf-1 Internal Ribosome Entry Segment Attains the Correct Structural Conformation for Function via Interactions with PTB and unr

Mitchell, S. A., Spriggs, K. A., Coldwell, M. J., Jackson, R. J., & Willis, A. E. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00093-5 · Cited by 259 · see citing works

Characterization of cDNAs encoding the polypyrimidine tract-binding protein.Preprint

Gil, A., Sharp, P. A., Jamison, S. F., & García-Blanco, M. A. (1991) · Genes & Development · doi:10.1101/gad.5.7.1224 · Cited by 248 · see citing works

A Xenopus Protein Related to hnRNP I Has a Role in Cytoplasmic RNA Localization

Cote, C. A., Gautreau, D., Denegre, J. M., Kress, T. L., Terry, N. A., & Mowry, K. L. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80345-7 · Cited by 240 · see citing works

Interaction of polypyrimidine tract-binding protein with the 5' noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation

Ali, N., & Siddiqui, A. (1995) · Journal of Virology · doi:10.1128/jvi.69.10.6367-6375.1995 · Cited by 236 · see citing works

Structural and mechanistic insights into hepatitis C viral translation initiation

Fraser, C. S. A., & Doudna, J. A. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1558 · Cited by 231 · see citing works

A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing

Polydorides, A. D., Okano, H. J., Yang, Y. Y. L., Stefani, G., & Darnell, R. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.110128397 · Cited by 230 · see citing works

A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart.

Ashiya, M., & Grabowski, P. J. (1997) · PubMed · Cited by 220 · see citing works

Post-transcriptional regulation: The dawn of PTB

Valcárcel, J., & Gebauer, F. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00361-7 · Cited by 201 · see citing works

Alternative mechanisms of initiating translation of mammalian mRNAs

Jackson, R. J. (2005) · Biochemical Society Transactions · doi:10.1042/bst20051231 · Cited by 200 · see citing works

Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein

Xie, J., Lee, J.-A., Kress, T. L., Mowry, K. L., & Black, D. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432696100 · Cited by 178 · see citing works

Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome

Sharma, S., Kohlstaedt, L. A., Damianov, A., Rio, D. C., & Black, D. L. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1375 · Cited by 177 · see citing works

Multiple RRMs Contribute to RNA Binding Specificity and Affinity for Polypyrimidine Tract Binding Protein

Pérez, I. C., McAfee, J. G., & Patton, J. G. (1997) · Biochemistry · doi:10.1021/bi9711745 · Cited by 174 · see citing works

Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis

Knoch, K.-P., Bergert, H., Borgonovo, B., Saeger, H., Altkrüger, A., Verkade, P., & Solimena, M. (2004) · Nature Cell Biology · doi:10.1038/ncb1099 · Cited by 171 · see citing works

Polypyrimidine Tract Binding Protein Blocks the 5′ Splice Site-Dependent Assembly of U2AF and the Prespliceosomal E Complex

Sharma, S., Falick, A. M., & Black, D. L. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.07.014 · Cited by 165 · see citing works

Polypyrimidine Tract Binding Protein Regulates IRES-Mediated Gene Expression during Apoptosis

Bushell, M., Stoneley, M., Kong, Y. W., Hamilton, T. L., Spriggs, K. A., Dobbyn, H. C., Qin, X., Sarnow, P., & Willis, A. E. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.06.012 · Cited by 164 · see citing works

Internal ribosome entry segment-mediated translation during apoptosis: the role of IRES-trans-acting factors

Spriggs, K. A., Bushell, M., Mitchell, S. A., & Willis, A. E. (2005) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401642 · Cited by 163 · see citing works

Polypyrimidine Tract Binding Protein Modulates Efficiency of Polyadenylation

Castelo‐Branco, P., Furger, A., Wollerton, M., Smith, C. W. J., Moreira, A., & Proudfoot, N. J. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.10.4174-4183.2004 · Cited by 162 · see citing works

Control of Insulin mRNA Stability in Rat Pancreatic Islets

Tillmar, L., Carlsson, C., & Welsh, N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108340200 · Cited by 161 · see citing works

Protein Factor Requirements of the Apaf-1 Internal Ribosome Entry Segment: Roles of Polypyrimidine Tract Binding Protein and upstream of N-ras

Mitchell, S. A., Brown, E. C., Coldwell, M. J., Jackson, R. J., & Willis, A. E. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.10.3364-3374.2001 · Cited by 153 · see citing works

Polypyrimidine Tract-Binding Protein Positively Regulates Inclusion of an Alternative 3′-Terminal Exon

Lou, H. J., Helfman, D. M., Gagel, R. F., & Berget, S. M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.78 · Cited by 149 · see citing works

Translational control of retroviruses

Balvay, L., López‐Lastra, M., Sargueil, B., Darlix, J., & Ohlmann, T. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1599 · Cited by 142 · see citing works

Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry.Preprint

Mitchell, S. A., Spriggs, K. A., Bushell, M., Evans, J. R., Stoneley, M., Quesne, J. L., Spriggs, R. V., & Willis, A. (2005) · Genes & Development · doi:10.1101/gad.339105 · Cited by 142 · see citing works

Differential alternative splicing activity of isoforms of polypyrimidine tract binding protein (PTB)

Wollerton, M., Gooding, C., Robinson, F., Brown, E. C., Jackson, R. J., & Smith, C. W. J. (2001) · RNA · doi:10.1017/s1355838201010214 · Cited by 132 · see citing works

The polypyrimidine tract binding protein (PTB) requirement for internal initiation of translation of cardiovirus RNAs is conditional rather than absolute

Kaminski, A., & Jackson, R. J. (1998) · RNA · doi:10.1017/s1355838298971898 · Cited by 131 · see citing works

Transient Expression of Cellular Polypyrimidine-Tract Binding Protein Stimulates Cap-Independent Translation Directed by Both Picornaviral and Flaviviral Internal Ribosome Entry Sites In Vivo

Gosert, R., Chang, K. H., Rijnbrand, R. C. A., Yi, M., Sangar, D. V., & Lemon, S. M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.5.1583-1595.2000 · Cited by 129 · see citing works

Thymocytes in Thy-1−/− mice show augmented TCR signaling and impaired differentiation

Hueber, A., Bernard, A.-M., Langlet, C., Marguet, D., Massol, P., Foa, C., Brun, N., Garcia, S., Stewart, C. L., Pierres, M., et al. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00300-9 · Cited by 120 · see citing works

Structural analysis of the interaction of the pyrimidine tract-binding protein with the internal ribosomal entry site of encephalomyocarditis virus and foot-and-mouth disease virus RNAs.

KOLUPAEVA, V. G., Hellen, C. U. T., & Shatsky, I. N. (1996) · PubMed · Cited by 120 · see citing works

Exon repression by polypyrimidine tract binding protein

Amir-Ahmady, B., Boutz, P. L., Markovtsov, V. V., Phillips, M. L., & Black, D. L. (2005) · RNA · doi:10.1261/rna.2250405 · Cited by 118 · see citing works

Cell‐specific proteins regulate viral RNA translation and virus‐induced disease

Pilipenko, E. V., Viktorova, E. G., Guest, S. T., Agol, V. I., & Roos, R. P. (2001) · The EMBO Journal · doi:10.1093/emboj/20.23.6899 · Cited by 113 · see citing works

Isolation of a Mammalian Homologue of a Fission Yeast Differentiation Regulator

Yamamoto, H., Tsukahara, K., Kanaoka, Y., Jinno, S., & Okayama, H. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3829 · Cited by 112 · see citing works

A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain

Rideau, A., Gooding, C., Simpson, P. J., Monie, T. P., Lorenz, M., Hüttelmaier, S., Singer, R. H., Matthews, S., Curry, S., & Smith, C. W. J. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1137 · Cited by 101 · see citing works

Molecular Mechanisms of Attenuation of the Sabin Strain of Poliovirus Type 3

Guest, S., Pilipenko, E., Sharma, K., Chumakov, K., & Roos, R. P. (2004) · Journal of Virology · doi:10.1128/jvi.78.20.11097-11107.2004 · Cited by 101 · see citing works

Structure and RNA Interactions of the N-Terminal RRM Domains of PTB

Simpson, P. J., Monie, T. P., Szendröi, A., Davydova, N., Tyzack, J. K., Conte, M. R., Read, C. M., Cary, P. D., Svergun, D. I., Konarev, P. V., et al. (2004) · Structure · doi:10.1016/j.str.2004.07.008 · Cited by 100 · see citing works

Bag-1 Internal Ribosome Entry Segment Activity Is Promoted by Structural Changes Mediated by Poly(rC) Binding Protein 1 and Recruitment of Polypyrimidine Tract Binding Protein 1

Pickering, B. M., Mitchell, S. A., Spriggs, K. A., Stoneley, M., & Willis, A. E. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.12.5595-5605.2004 · Cited by 94 · see citing works

A multi‐protein complex containing cold shock domain (Y‐box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA

Coles, L. S., Bartley, M. A., Bert, A. G., Hunter, J., Polyak, S. W., Diamond, P., Vadas, M. A., & Goodall, G. J. (2004) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.2003.03968.x · Cited by 93 · see citing works

Specific trans-acting proteins interact with auxiliary RNA polyadenylation elements in the COX-2 3′-UTR

Hall‐Pogar, T., Liang, S., Hague, L. K., & Lutz, C. S. (2007) · RNA · doi:10.1261/rna.577707 · Cited by 90 · see citing works

Determination of functional domains in polypyrimidine-tract-binding protein

Oh, Y. L., Hahm, B., Kim, Y. K., Lee, H. K., Lee, J. W., Ok.-K., S. O. N. G., Tsukiyama–Kohara, K., Kohara, M., Nomoto, A., & Jang, S. K. (1998) · Biochemical Journal · doi:10.1042/bj3310169 · Cited by 90 · see citing works

Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translation

Song, Y., Tzima, E., Ochs, K., Bassili, G., Trusheim, H., Linder, M., Preissner, K. T., & Niepmann, M. (2005) · RNA · doi:10.1261/rna.7430405 · Cited by 88 · see citing works

The Polypyrimidine Tract-binding Protein (PTB) Is Involved in the Post-transcriptional Regulation of Human Inducible Nitric Oxide Synthase Expression

Pautz, A., Linker, K., Hubrich, T., Korhonen, R., Altenhöfer, S., & Kleinert, H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603915200 · Cited by 87 · see citing works

The polypyrimidine tract-binding protein stimulates HIF-1 IRES-mediated translation during hypoxia

Schepens, B. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki1000 · Cited by 87 · see citing works

cAMP-dependent phosphorylation of PTB1 promotes the expression of insulin secretory granule proteins in β cells

Knoch, K.-P., Meisterfeld, R., Kersting, S., Bergert, H., Altkrüger, A., Wegbrod, C., Jäger, M., Saeger, H., & Solimena, M. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2005.12.008 · Cited by 85 · see citing works

Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication

Domitrovich, A. M., Diebel, K. W., Ali, N., Sarker, S. F., & Siddiqui, A. (2005) · Virology · doi:10.1016/j.virol.2005.02.009 · Cited by 85 · see citing works

Delineation of a Novel Pathway That Regulates CD154 (CD40 Ligand) Expression

Hamilton, B. J., Genin, A., Cron, R. Q., & Rigby, W. F. C. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.23.2.510-525.2003 · Cited by 82 · see citing works

Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors

Gama‐Carvalho, M., Barbosa‐Morais, N. L., Brodsky, A. S., Silver, P. A., & Carmo‐Fonseca, M. (2006) · Genome biology · doi:10.1186/gb-2006-7-11-r113 · Cited by 79 · see citing works

Nucleocytoplasmic Shuttling of Polypyrimidine Tract-binding Protein Is Uncoupled from RNA Export

Kamath, R. V., Leary, D. J., & Huang, S. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.12.3808 · Cited by 75 · see citing works

UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein

Cornelis, S. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki611 · Cited by 68 · see citing works

Regulation of BAG-1 IRES-mediated translation following chemotoxic stress

Dobbyn, H. C., Hill, K., Hamilton, T. L., Spriggs, K. A., Pickering, B. M., Coldwell, M. J., de Moor, C. H., Bushell, M., & Willis, A. E. (2007) · Oncogene · doi:10.1038/sj.onc.1210723 · Cited by 67 · see citing works

Role of Polypyrimidine Tract Binding Protein in the Function of the Hepatitis B Virus Posttranscriptional Regulatory Element

Zang, W.-Q., Li, B., Huang, P., Lai, M. M. C., & Yen, T. S. B. (2001) · Journal of Virology · doi:10.1128/jvi.75.22.10779-10786.2001 · Cited by 65 · see citing works

Solving the Structure of PTB in Complex with Pyrimidine Tracts: An NMR Study of Protein–RNA Complexes of Weak Affinities†

Auweter, S., Oberstrass, F. C., & Allain, F. H. ‐. (2006) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.12.053 · Cited by 64 · see citing works

Hypoxia May Increase Rat Insulin mRNA Levels by Promoting Binding of the Polypyrimidine Tract-binding Protein (PTB) to the Pyrimidine-rich Insulin mRNA 3′-Untranslated Region

Tillmar, L., & Welsh, N. (2002) · Molecular Medicine · doi:10.1007/bf03402152 · Cited by 64 · see citing works

Conformation of Polypyrimidine Tract Binding Protein in Solution

Petoukhov, M. V., Monie, T. P., Allain, F. H. ‐., Matthews, S., Curry, S., & Svergun, D. I. (2006) · Structure · doi:10.1016/j.str.2006.04.005 · Cited by 62 · see citing works

A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2

Shen, H., Kan, J. L. C., Ghigna, C., Biamonti, G., & Green, M. R. (2004) · RNA · doi:10.1261/rna.5229704 · Cited by 58 · see citing works

The polypyrimidine tract-binding protein (PTB) is required for efficient replication of hepatitis C virus (HCV) RNA

Chang, K.-S., & Luo, G. G. (2005) · Virus Research · doi:10.1016/j.virusres.2005.06.012 · Cited by 58 · see citing works

The polypyrimidine tract binding protein is a monomer

Monie, T. P., Hernández, H., Robinson, C. V., Simpson, P. J., Matthews, S., & Curry, S. (2005) · RNA · doi:10.1261/rna.2214405 · Cited by 57 · see citing works

Relocalization of the polypyrimidine tract-binding protein during PKA-induced neurite growth

Ma, S., Liu, G., Sun, Y., & Xie, J. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2007.02.006 · Cited by 56 · see citing works

The Polypyrimidine Tract Binding Protein Is Required for Efficient Picornavirus Gene Expression and Propagation

Florez, P., Sessions, O. M., Wagner, E. J., Gromeier, M., & García-Blanco, M. A. (2005) · Journal of Virology · doi:10.1128/jvi.79.10.6172-6179.2005 · Cited by 50 · see citing works

Polypyrimidine Tract Binding Protein 2 Stabilizes Phosphoglycerate Kinase 2 mRNA in Murine Male Germ Cells by Binding to Its 3′UTR1

Xu, M., & Hecht, N. B. (2007) · Biology of Reproduction · doi:10.1095/biolreprod.107.060079 · Cited by 50 · see citing works

PTB Regulates the Processing of a 3′-Terminal Exon by Repressing both Splicing and Polyadenylation

Sommer, C., Lesimple, M., Méreau, A., Ménoret, S., Allo, M., & Hardy, S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.21.9595-9607.2005 · Cited by 45 · see citing works

Polypyrimidine-tract-binding Protein is a Component of the HCV RNA Replication Complex and Necessary for RNA Synthesis

Aizaki, H., Choi, K. S., Liu, M., Li, Y., & Lai, M. M. C. (2006) · Journal of Biomedical Science · doi:10.1007/s11373-006-9088-4 · Cited by 44 · see citing works

Characterization of the Nuclear Export Signal of Polypyrimidine Tract-binding Protein

Li, B., & Yen, T. S. B. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109686200 · Cited by 43 · see citing works

Polypyrimidine Tract-binding Proteins Are Cleaved by Caspase-3 during Apoptosis

Back, S. H., Shin, S., & Jang, S. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203887200 · Cited by 42 · see citing works

Alternative Splicing of Brain-Specific PTB Defines a Tissue-Specific Isoform Pattern That Predicts Distinct Functional Roles

Rahman, L., Bliskovski, V., Reinhold, W. C., & Zajac‐Kaye, M. (2002) · Genomics · doi:10.1006/geno.2002.6826 · Cited by 42 · see citing works

Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3′-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin

Tillmar, L., & Welsh, N. (2004) · Molecular and Cellular Biochemistry · doi:10.1023/b:mcbi.0000026059.56089.e4 · Cited by 32 · see citing works

Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content

Robinson, F., Jackson, R. J., & Smith, C. W. J. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001801 · Cited by 30 · see citing works

Inhibition of hepatitis C virus replication and expression by small interfering RNA targeting host cellular genes

Xue, Q., Ding, H., Liu, M.-X., Zhao, P., Gao, J., Ren, H., Liu, Y., & Qi, Z. (2007) · Archives of Virology · doi:10.1007/s00705-006-0905-x · Cited by 24 · see citing works

Increased expression of polypyrimidine tract binding protein results in higher insulin mRNA levels

Fred, R. G., & Welsh, N. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.12.147 · Cited by 11 · see citing works

Investigation of interactions of polypyrimidine tract-binding protein with artificial internal ribosome entry segments

Spriggs, K. A., Mitchell, S. A., & Willis, A. E. (2005) · Biochemical Society Transactions · doi:10.1042/bst0331483 · Cited by 11 · see citing works

Investigation of interactions of polypyrimidine tract-binding protein with artificial internal ribosome entry segments

Mitchell, S. A., Spriggs, K. A., & Willis, A. E. (2005) · Biochemical Society Transactions · doi:10.1042/bst20051483 · Cited by 9 · see citing works

Untitled work

Greber (1999) · doi:10.1002/(sici)1522-2683(19990101)20:4/5

A compendium of RNA-binding motifs for decoding gene regulation

Ray, D., Kazan, H., Cook, K. B., Weirauch, M. T., Najafabadi, H. S., Li, X., Gueroussov, S., Albu, M., Zheng, H., Yang, A., et al. (2013) · Nature · doi:10.1038/nature12311 · Cited by 1,480 · see citing works

Circular RNA-protein interactions: functions, mechanisms, and identification

Huang, A., Zheng, H., Wu, Z., Chen, M., & Huang, Y. (2020) · Theranostics · doi:10.7150/thno.42174 · Cited by 905 · see citing works

Mechanisms and Functions of Long Non-Coding RNAs at Multiple Regulatory Levels

Zhang, X., Wang, W., Zhu, W., Dong, J., Cheng, Y., Yin, Z., & Shen, F. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225573 · Cited by 878 · see citing works

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedPreprint

David, C. J., & Manley, J. L. (2010) · Genes & Development · doi:10.1101/gad.1973010 · Cited by 815 · see citing works

The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

Matoulkova, E., Michalova, E., Vojtesek, B., & Hrstka, R. (2012) · RNA Biology · doi:10.4161/rna.20231 · Cited by 357 · see citing works

HuR function in disease

Srikantan, S. (2012) · Frontiers in Bioscience · doi:10.2741/3921 · Cited by 353 · see citing works

To localize or not to localize: mRNA fate is in 3′UTR ends

Andreassi, C., & Riccio, A. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.06.001 · Cited by 338 · see citing works

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

Llorian, M., Schwartz, S., Clark, T. A., Hollander, D., Tan, L.-Y., Spellman, R., Gordon, A., Schweitzer, A. C., de la Grange, P., Ast, G., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1881 · Cited by 263 · see citing works

IRES-mediated cap-independent translation, a path leading to hidden proteome

Yang, Y., & Wang, Z. (2019) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjz091 · Cited by 260 · see citing works

Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2

Caruso, P. L., Dunmore, B. J., Schlosser, K., Schoors, S., dos Santos, C. C., Perez‐Iratxeta, C., Lavoie, J. R., Zhang, H., Long, L., Flockton, A. R., et al. (2017) · Circulation · doi:10.1161/circulationaha.117.028034 · Cited by 258 · see citing works

Post-transcriptional control of circadian rhythms

Kojima, S., Shingle, D. L., & Green, C. B. (2011) · Journal of Cell Science · doi:10.1242/jcs.065771 · Cited by 247 · see citing works

Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA

Chen, M., Zhang, J., & Manley, J. L. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-2513 · Cited by 237 · see citing works

Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

Keppetipola, N., Sharma, S., Li, Q., & Black, D. L. (2012) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2012.691456 · Cited by 201 · see citing works

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain

Licatalosi, D. D., Yano, M., Fak, J. J., Mele, A., Grabinski, S. E., Zhang, C., & Darnell, R. B. (2012) · Genes & Development · doi:10.1101/gad.191338.112 · Cited by 193 · see citing works

Translational control in cellular and developmental processes

Kong, J., & Lasko, P. F. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3184 · Cited by 189 · see citing works

Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay

Zhang, L., Yang, Z., Trottier, J., Barbier, O., & Wang, L. (2016) · Hepatology · doi:10.1002/hep.28882 · Cited by 185 · see citing works

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

Li, Q., Zheng, S., Han, A., Lin, C.-H., Stoilov, P., Fu, X.-D., & Black, D. L. (2014) · eLife · doi:10.7554/elife.01201 · Cited by 174 · see citing works

New Insights into Vinculin Function and Regulation

Peng, X. L., Nelson, E. S., Maiers, J. L., & DeMali, K. A. (2011) · International review of cytology · doi:10.1016/b978-0-12-386043-9.00005-0 · Cited by 174 · see citing works

Cold shock proteins: from cellular mechanisms to pathophysiology and disease

Lindquist, J. A., & Mertens, P. R. (2018) · Cell Communication and Signaling · doi:10.1186/s12964-018-0274-6 · Cited by 174 · see citing works

Cleavage and polyadenylation: Ending the message expands gene regulation

Neve, J., Patel, R. J., Wang, Z., Louey, A., & Furger, A. (2017) · RNA Biology · doi:10.1080/15476286.2017.1306171 · Cited by 169 · see citing works

Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB

Coelho, M. B., Attig, J., Bellora, N., König, J., Hallegger, M., Kayikci, M., Eyras, E., Ule, J., & Smith, C. W. J. (2015) · The EMBO Journal · doi:10.15252/embj.201489852 · Cited by 163 · see citing works

Evolutionary Conservation and Expression of Human RNA-Binding Proteins and Their Role in Human Genetic Disease

Gerstberger, S. C., Hafner, M., Ascano, M., & Tuschl, T. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-1221-6_1 · Cited by 145 · see citing works

Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells

Khandelia, P., Yap, K., & Makeyev, E. V. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103532108 · Cited by 147 · see citing works

RNA binding protein/RNA element interactions and the control of translation

Pichon, X., A. Wilson, L., Stoneley, M., Bastide, A., A King, H., Somers, J., & E Willis, A. (2012) · Current Protein & Peptide Science · doi:10.2174/138920312801619475 · Cited by 144 · see citing works

The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis

Shu, B., Zhou, Y., Li, H., Zhang, R., He, C., & Yang, X. (2021) · Cell Death Discovery · doi:10.1038/s41420-021-00756-x · Cited by 144 · see citing works

Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs

Abdelmohsen, K., Tominaga, K., Lee, E. K., Srikantan, S., Kang, M. J., Kim, M. M., Selimyan, R., Martindale, J. L., Yang, X., Carrier, F., et al. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr488 · Cited by 133 · see citing works

The role of IRES trans-acting factors in regulating translation initiation

King, H. A., Cobbold, L. C., & Willis, A. E. (2010) · Biochemical Society Transactions · doi:10.1042/bst0381581 · Cited by 132 · see citing works

New Insights into Functional Roles of the Polypyrimidine Tract-Binding Protein

Romanelli, M. G., Diani, E., & Lievens, P. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141122906 · Cited by 131 · see citing works

The human RBPome: From genes and proteins to human disease

Neelamraju, Y., Hashemikhabir, S., & Janga, S. C. (2015) · Journal of Proteomics · doi:10.1016/j.jprot.2015.04.031 · Cited by 119 · see citing works

The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA

Nowak, U. M., Matthews, A. J., Zheng, S., & Chaudhuri, J. (2010) · Nature Immunology · doi:10.1038/ni.1977 · Cited by 121 · see citing works

Diverse roles of RNA‐binding proteins in cancer traits and their implications in gastrointestinal cancers

Masuda, K., & Kuwano, Y. (2018) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1520 · Cited by 115 · see citing works

Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs

Gorospe, M., Tominaga, K., Wu, X., Fähling, M., & Ivan, M. (2011) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2011.00007 · Cited by 109 · see citing works

Competitive Regulation of Nucleolin Expression by HuR and miR-494

Tominaga, K., Srikantan, S., Lee, E. K., Subaran, S. S., Martindale, J. L., Abdelmohsen, K., & Gorospe, M. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05955-11 · Cited by 106 · see citing works

NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif

Kuwano, Y., Pullmann, R., Marasa, B. S., Abdelmohsen, K., Lee, E. K., Yang, X., Martindale, J. L., Zhan, M., & Gorospe, M. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp861 · Cited by 105 · see citing works

Trans‐acting translational regulatory RNA binding proteins

Harvey, R. F., Smith, T. S., Mulroney, T. E., Queiroz, R. M. L., Pizzinga, M., Dezi, V., Villanueva, E., Ramakrishna, M., Lilley, K. S., & Willis, A. E. (2018) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1465 · Cited by 104 · see citing works

Polypyrimidine Tract Binding Protein Homologs from Arabidopsis Are Key Regulators of Alternative Splicing with Implications in Fundamental Developmental Processes

Rühl, C., Stauffer, E., Kahles, A., Wagner, G., Drechsel, G., Rätsch, G., & Wachter, A. (2012) · The Plant Cell · doi:10.1105/tpc.112.103622 · Cited by 96 · see citing works

Polypyrimidine Tract Binding Protein Stabilizes the Encephalomyocarditis Virus IRES Structure via Binding Multiple Sites in a Unique Orientation

Kafasla, P., Morgner, N., Pöyry, T. A. A., Curry, S., Robinson, C. V., & Jackson, R. J. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.04.015 · Cited by 94 · see citing works

Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development

Liu, J., Li, Y., Tong, J., Gao, J., Guo, Q., Zhang, L., Wang, B., Zhao, H., Wang, H., Jiang, E., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06883-x · Cited by 93 · see citing works

Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus

Flather, D. P., & Semler, B. L. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00594 · Cited by 92 · see citing works

Defining the roles and interactions of PTB

Kafasla, P., Mickleburgh, I., Llorian, M., Coelho, M. B., Gooding, C., Cherny, D., Joshi, A., Kotik-Kogan, O., Curry, S., Eperon, I. C., et al. (2012) · Biochemical Society Transactions · doi:10.1042/bst20120044 · Cited by 92 · see citing works

Polypyrimidine tract‐binding protein stimulates the poliovirus IRES by modulating eIF4G binding

Kafasla, P., Morgner, N., Robinson, C. V., & Jackson, R. J. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.231 · Cited by 92 · see citing works

RNA–protein interactions in vivo: global gets specific

Änkö, M., & Neugebauer, K. M. (2012) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2012.02.005 · Cited by 88 · see citing works

Quantitative Map of Proteome Dynamics during Neuronal Differentiation

Frese, C. K., Mikhaylova, M., Stucchi, R., Gautier, V., Liu, Q., Mohammed, S., Heck, A. J. R., Altelaar, M. A. F., & Hoogenraad, C. C. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.01.025 · Cited by 88 · see citing works

PTBP1‐dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis

Izaguirre, D. I., Zhu, W., Hai, T., Beird, H. C., Krahe, R., & Cote, G. J. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20859 · Cited by 88 · see citing works

The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers

Monzón‐Casanova, E., Screen, M., Díaz‐Muñoz, M. D., Coulson, R., Bell, S. E., Lamers, G., Solimena, M., Smith, C. W. J., & Turner, M. (2018) · Nature Immunology · doi:10.1038/s41590-017-0035-5 · Cited by 85 · see citing works

Polypyrimidine tract-binding proteins of potato mediate tuberization through an interaction with StBEL5 RNA

Cho, S. K., Sharma, P., Butler, N., Kang, I., Shah, S. N., Rao, A. G., & Hannapel, D. J. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv389 · Cited by 86 · see citing works

RBM4 down-regulates PTB and antagonizes its activity in muscle cell–specific alternative splicing

Lin, J.-C., & Tarn, W. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201007131 · Cited by 86 · see citing works

Differential protein occupancy profiling of the mRNA transcriptome

Schueler, M., Munschauer, M., Gregersen, L. H., Finzel, A., Loewer, A., Chen, W., Landthaler, M., & Dieterich, C. (2014) · Genome biology · doi:10.1186/gb-2014-15-1-r15 · Cited by 81 · see citing works

High-throughput characterization of protein-RNA interactions

Cook, K. B., Hughes, T., & Morris, Q. (2014) · Briefings in Functional Genomics · doi:10.1093/bfgp/elu047 · Cited by 82 · see citing works

Polypyrimidine tract-binding protein homologues from Arabidopsis underlie regulatory circuits based on alternative splicing and downstream control

Stauffer, E., Westermann, A. J., Wagner, G., & Wachter, A. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04321.x · Cited by 83 · see citing works

Nuclear proteins hijacked by mammalian cytoplasmic plus strand RNA viruses

Lloyd, R. E. (2015) · Virology · doi:10.1016/j.virol.2015.03.001 · Cited by 81 · see citing works

The hnRNA-Binding Proteins hnRNP L and PTB Are Required for Efficient Translation of the Cat-1 Arginine/Lysine Transporter mRNA during Amino Acid Starvation

Majumder, M., Yaman, İ., Gaccioli, F., Zeenko, V. V., Wang, C., Caprara, M. G., Venema, R. C., Komar, A. A., Snider, M. D., & Hatzoglou, M. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01774-08 · Cited by 81 · see citing works

RNA ‐binding proteins, neural development and the addictions

Bryant, C. D., & Yazdani, N. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12273 · Cited by 79 · see citing works

RNA‐binding proteins implicated in the hypoxic response

Masuda, K., Abdelmohsen, K., & Gorospe, M. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00842.x · Cited by 78 · see citing works

LncRNA MACC1-AS1 sponges multiple miRNAs and RNA-binding protein PTBP1

Zhang, X., Zhou, Y., Chen, S., Li, W., Chen, W., & Gu, W. (2019) · Oncogenesis · doi:10.1038/s41389-019-0182-7 · Cited by 78 · see citing works

TIA1 Prevents Skipping of a Critical Exon Associated with Spinal Muscular Atrophy

Singh, N. N., Seo, J., Ottesen, E. W., Shishimorova, M., Bhattacharya, D., & Singh, R. N. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00945-10 · Cited by 78 · see citing works

Ptbp2 Controls an Alternative Splicing Network Required for Cell Communication during Spermatogenesis

Hannigan, M. M., Zagore, L. L., & Licatalosi, D. D. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.05.089 · Cited by 78 · see citing works

The Polypyrimidine Tract-Binding Protein Affects Coronavirus RNA Accumulation Levels and Relocalizes Viral RNAs to Novel Cytoplasmic Domains Different from Replication-Transcription Sites

Sola, I., Galán, C., Mateos‐Gómez, P. A., Palacio, L., Zúñiga, S., Cruz, J. L. G., Almazán, F., & Enjuanes, L. (2011) · Journal of Virology · doi:10.1128/jvi.00195-11 · Cited by 74 · see citing works

Proteomics of methyl jasmonate induced defense response in maize leaves against Asian corn borer

Zhang, Y. T., Zhang, Y. L., Chen, S. X., Yin, G., Yang, Z. Z., Lee, S., Liu, C. G., Zhao, D., Ma, Y. K., Song, F. Q., et al. (2015) · BMC Genomics · doi:10.1186/s12864-015-1363-1 · Cited by 70 · see citing works

An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2+/PTBP1+ pan-adenocarcinoma

Feng, Z., Zhang, X., Zhou, J., Li, Q., Chu, L., Di, G., Xu, Z., Chen, Q., Wang, M., Jiang, X., et al. (2023) · Nature Cancer · doi:10.1038/s43018-023-00650-8 · Cited by 69 · see citing works

Minireview: Posttranscriptional Regulation of the Insulin and Insulin-Like Growth Factor Systems

Lee, E. K., & Gorospe, M. (2009) · Endocrinology · doi:10.1210/en.2009-1123 · Cited by 69 · see citing works

SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies

Toki, N., Takahashi, H., Sharma, H., Valentine, M. N. Z., Rahman, M. F., Zucchelli, S., Gustincich, S., & Carninci, P. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa814 · Cited by 68 · see citing works

Internal translation initiation of picornaviruses and hepatitis C virus

Niepmann, M. (2009) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2009.05.002 · Cited by 68 · see citing works

Insights into the Biology of IRES Elements through Riboproteomic Approaches

Pacheco, A., & Martı́nez-Salas, E. (2010) · BioMed Research International · doi:10.1155/2010/458927 · Cited by 67 · see citing works

PBRM1, SETD2 and BAP1 — the trinity of 3p in clear cell renal cell carcinoma

Walton, J., Lawson, K. A., Prinos, P., Finelli, A., Arrowsmith, C. H., & Ailles, L. (2022) · Nature Reviews Urology · doi:10.1038/s41585-022-00659-1 · Cited by 68 · see citing works

Viral Subversion of Host Functions for Picornavirus Translation and RNA Replication

Chase, A. J., & Semler, B. L. (2012) · Future Virology · doi:10.2217/fvl.12.2 · Cited by 64 · see citing works

Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis

Fingerhut, J. M., Moran, J. V., & Yamashita, Y. M. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008028 · Cited by 62 · see citing works

PTBP1 ‐targeting microRNAs regulate cancer‐specific energy metabolism through the modulation of PKM1/M2 splicing

Taniguchi, K., Uchiyama, K., & Akao, Y. (2020) · Cancer Science · doi:10.1111/cas.14694 · Cited by 59 · see citing works

LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy

Wang, Y., Li, Z., Xu, S., Li, W., Chen, M., Jiang, M., & Fan, X. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04509-1 · Cited by 60 · see citing works

The Sequence and Structure Determine the Function of Mature Human miRNAs

Rolle, K., Piwecka, M., Belter, A., Wawrzyniak, D., Jeleniewicz, J., Barciszewska, M. Z., & Barciszewski, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151246 · Cited by 60 · see citing works

Functional Analysis of RNA Structures Present at the 3′ Extremity of the Murine Norovirus Genome: the Variable Polypyrimidine Tract Plays a Role in Viral Virulence

Bailey, D., Karakasiliοtis, I., Vashist, S., Chung, L. M. W., Reese, J., McFadden, N., Benson, A., Yarovinsky, F., Peter Simmonds, K., & Goodfellow, I. (2010) · Journal of Virology · doi:10.1128/jvi.02053-09 · Cited by 59 · see citing works

RNA-Binding Protein PTB and MicroRNA-221 Coregulate AdipoR1 Translation and Adiponectin Signaling

Lustig, Y., Barhod, E., Ashwal-Fluss, R., Gordin, R., Shomron, N., Umansky, K. B., Hemi, R., Karasik, A., & Kanety, H. (2013) · Diabetes · doi:10.2337/db13-1032 · Cited by 56 · see citing works

The Role of Polypyrimidine Tract-Binding Proteins and Other hnRNP Proteins in Plant Splicing Regulation

Wachter, A., Rühl, C., & Stauffer, E. (2012) · Frontiers in Plant Science · doi:10.3389/fpls.2012.00081 · Cited by 55 · see citing works

Identification and complete genome characterization of a novel picornavirus in turkey (Meleagris gallopavo)

Boros, Á., Nemes, C., Pankovics, P., Kapusinszky, B., Delwart, E., & Reuter, G. (2012) · Journal of General Virology · doi:10.1099/vir.0.043224-0 · Cited by 54 · see citing works

Inhibition of Poliovirus-Induced Cleavage of Cellular Protein PCBP2 Reduces the Levels of Viral RNA Replication

Chase, A. J., Daijogo, S., & Semler, B. L. (2013) · Journal of Virology · doi:10.1128/jvi.02503-13 · Cited by 54 · see citing works

Polypyrimidine tract-binding protein is relocated to the cytoplasm and is required during dengue virus infection in Vero cells

Agis-Juárez, R. A., Galván, I. J., Medina, F., Daikoku, T., Padmanabhan, R., Ludert, J. E., & del Angel, R. M. (2009) · Journal of General Virology · doi:10.1099/vir.0.013433-0 · Cited by 54 · see citing works

Oncoprotein AEG-1 is an endoplasmic reticulum RNA-binding protein whose interactome is enriched in organelle resident protein-encoding mRNAs

Hsu, J. C.-C., Reid, D. W., Hoffman, A. M., Sarkar, D., & Nicchitta, C. V. (2018) · RNA · doi:10.1261/rna.063313.117 · Cited by 51 · see citing works

Small molecules that interact with RNA : riboswitch‐based gene control and its involvement in metabolic regulation in plants and algae

Bocobza, S. E., & Aharoni, A. (2014) · The Plant Journal · doi:10.1111/tpj.12540 · Cited by 52 · see citing works

The human insulin receptor mRNA contains a functional internal ribosome entry segment

Spriggs, K. A., Cobbold, L. C., Ridley, S. H., Coldwell, M. J., Bottley, A., Bushell, M., Willis, A. E., & Siddle, K. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp623 · Cited by 51 · see citing works

Insights into Dengue Virus Genome Replication

Alcaráz‐Estrada, S. L., Yocupicio‐Monroy, M., & del Angel, R. M. (2010) · Future Virology · doi:10.2217/fvl.10.49 · Cited by 50 · see citing works

PTBP1 modulation of MCL1 expression regulates cellular apoptosis induced by antitubulin chemotherapeutics

Cui, J., & Placzek, W. J. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.60 · Cited by 50 · see citing works

H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis

Zhang, L., Yang, Z., Huang, W., & Wu, J. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1423-6 · Cited by 50 · see citing works

Polypyrimidine tract-binding protein influences negative strand RNA synthesis of dengue virus

Jiang, L., Yao, H., Duan, X., Lü, X., & Liu, Y. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.05.036 · Cited by 47 · see citing works

Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence

Reid, D. C., Chang, B. L., Gunderson, S., Sugden, L. A., Thompson, W. A., & Fairbrother, W. G. (2009) · RNA · doi:10.1261/rna.1821809 · Cited by 48 · see citing works

A miR‐194/PTBP1/CCND3 axis regulates tumor growth in human hepatocellular carcinoma

Kang, H., Heo, S., Shin, J. J., Ji, E., Tak, H., Ahn, S., Lee, K. J., Lee, E. K., & Kim, W. (2019) · The Journal of Pathology · doi:10.1002/path.5325 · Cited by 47 · see citing works

The Long Non-coding RNAs: Paramount Regulators of the NLRP3 Inflammasome

Menon, M. P., & Hua, K. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.569524 · Cited by 47 · see citing works

AID targeting is dependent on RNA polymerase II pausing

Kenter, A. L. (2012) · Seminars in Immunology · doi:10.1016/j.smim.2012.06.001 · Cited by 47 · see citing works

miR-124-3p is a chronic regulator of gene expression after brain injury

Vuokila, N., Łukasiuk, K., Bot, A. M., van Vliet, E. A., Aronica, E., Pitkänen, A., & Puhakka, N. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2911-z · Cited by 45 · see citing works

PTB-AS, a Novel Natural Antisense Transcript, Promotes Glioma Progression by Improving PTBP1 mRNA Stability with SND1

Zhu, L., Wei, Q., Qi, Y., Ruan, X., Wu, F., Li, L., Zhou, J., Liu, W., Jiang, T., Zhang, J., et al. (2019) · Molecular Therapy · doi:10.1016/j.ymthe.2019.05.023 · Cited by 45 · see citing works

Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons

DeBoer, E., Kraushar, M. L., Hart, R. P., & Rašin, M. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.05.042 · Cited by 45 · see citing works

Roles of RNA-binding Proteins and Post-transcriptional Regulation in Driving Male Germ Cell Development in the Mouse

Licatalosi, D. D. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-29073-7_6 · Cited by 45 · see citing works

Multiple Mobile mRNA Signals Regulate Tuber Development in Potato

Hannapel, D. J., & Banerjee, A. K. (2017) · Plants · doi:10.3390/plants6010008 · Cited by 45 · see citing works

Alternative mechanisms of translation initiation: An emerging dynamic regulator of the proteome in health and disease

James, C. C., & Smyth, J. W. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.09.054 · Cited by 45 · see citing works

Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing

Joshi, A., Coelho, M. B., Kotik-Kogan, O., Simpson, P. J., Matthews, S., Smith, C. W. J., & Curry, S. (2011) · Structure · doi:10.1016/j.str.2011.09.020 · Cited by 44 · see citing works

The Domains of Polypyrimidine Tract Binding Protein Have Distinct RNA Structural Preferences

Clerté, C., & Hall, K. B. (2009) · Biochemistry · doi:10.1021/bi8016872 · Cited by 44 · see citing works

The Emerging Role of the RBM20 and PTBP1 Ribonucleoproteins in Heart Development and Cardiovascular Diseases

Fochi, S., Lorenzi, P., Galasso, M., Stefani, C., Trabetti, E., Zipeto, D., & Romanelli, M. G. (2020) · Genes · doi:10.3390/genes11040402 · Cited by 42 · see citing works

Resveratrol, by Modulating RNA Processing Factor Levels, Can Influence the Alternative Splicing of Pre-mRNAs

Markus, M. A., Marques, F. Z., & Morris, B. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028926 · Cited by 41 · see citing works

PTBP3 promotes malignancy and hypoxia‐induced chemoresistance in pancreatic cancer cells by ATG12 up‐regulation

Ma, J., Weng, L., Jia, Y., Liu, B., Wu, S., Xue, L., Yin, X., Mao, A., Wang, Z., & Shang, M. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14896 · Cited by 41 · see citing works

LncRNAs and their RBPs: How to influence the fate of stem cells?

Zhao, C., Xie, W. J., Zhu, H., Zhao, M., Liu, W., Wu, Z., Wang, L., Zhu, B., Li, S., Zhou, Y., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02851-x · Cited by 40 · see citing works

PTBP1 mRNA isoforms and regulation of their translation

de Tacca, L. A., Pulos-Holmes, M. C., Floor, S. N., & Cate, J. H. D. (2019) · RNA · doi:10.1261/rna.070193.118 · Cited by 39 · see citing works

New Insights into Functional Roles of the Polypyrimidine Tract-Binding Protein

Romanelli, M. G., Diani, E., & Lievens, P. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141122906 · Cited by 131 · see citing works

PTB (polypyrimidine tract binding protein, 58 kDa)

(2008) · Springer eBooks · doi:10.1007/978-1-4020-6754-9_13788

Defining the roles and interactions of PTB

Kafasla, P., Mickleburgh, I., Llorian, M., Coelho, M. B., Gooding, C., Cherny, D., Joshi, A., Kotik-Kogan, O., Curry, S., Eperon, I. C., et al. (2012) · Biochemical Society Transactions · doi:10.1042/bst20120044 · Cited by 92 · see citing works

Post-transcriptional regulation: The dawn of PTB

Valcárcel, J., & Gebauer, F. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00361-7 · Cited by 201 · see citing works

Differential alternative splicing activity of isoforms of polypyrimidine tract binding protein (PTB)

Wollerton, M., Gooding, C., Robinson, F., Brown, E. C., Jackson, R. J., & Smith, C. W. J. (2001) · RNA · doi:10.1017/s1355838201010214 · Cited by 132 · see citing works