Bonnefond, Amélie

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

DIAGRAM Consortium, Dupuis, J., GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, the MAGIC investigators, Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,166

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

Bouatia-Naji, N., Bonnefond, A., Cavalcanti-Proença, C., Sparsø, T., Holmkvist, J., Marchand, M., Delplanque, J., Lobbens, S., Rocheleau, G., Durand, E., et al. (2009) · Nature Genetics

Circadian rhythm and melatoninGenetic Associations and Epidemiology

Cited by 611

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., et al. (2017) · The Lancet Diabetes & Endocrinology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 380

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

The Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC), Bonnefond, A., Clément, N., Fawcett, K., Yengo, L., Vaillant, E., Guillaume, J.-L., Dechaume, A., Payne, F., Roussel, R., et al. (2012) · Nature Genetics

Circadian rhythm and melatoninGenetic Associations and Epidemiology

Cited by 363

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Low copy number of the salivary amylase gene predisposes to obesity

Falchi, M., El-Sayed Moustafa, J. S., Takousis, P., Pesce, F., Bonnefond, A., Andersson-Assarsson, J. C., Sudmant, P. H., Dorajoo, R., Al-Shafai, M. N., Bottolo, L., et al. (2014) · Nature Genetics

Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology

Cited by 254

Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications

Bonnefond, A., Skrobek, B., Lobbens, S., Eury, E., Thuillier, D., Cauchi, S., Lantieri, O., Balkau, B., Riboli, E., Marre, M., et al. (2013) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 139

Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study

Yu Chen, H., Dina, C., Small, A. M., Shaffer, C. M., Levinson, R. T., Helgadóttir, A., Capoulade, R., Munter, H. M., Martinsson, A., Cairns, B. J., et al. (2023) · European Heart Journal

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 116

Genetic Association Analyses Highlight IL6 , ALPL , and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis

Thériault, S., Dina, C., Messika-Zeitoun, D., Le Scouarnec, S., Capoulade, R., Gaudreault, N., Rigade, S., Li, Z., Simonet, F., Lamontagne, M., et al. (2019) · Circulation: Genomic and Precision Medicine

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 90

The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward

Ndiaye, F. K., Huyvaert, M., Ortalli, A., Canouil, M., Lecoeur, C., Verbanck, M., Lobbens, S., Khamis, A., Marselli, L., Marchetti, P., et al. (2020) · International Journal of Obesity

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 66

Type 2 diabetes–associated variants of the MT 2 melatonin receptor affect distinct modes of signaling

Karamitri, A., Plouffe, B., Bonnefond, A., Chen, M., Gallion, J., Guillaume, J.-L., Hegron, A., Boissel, M., Canouil, M., Langenberg, C., et al. (2018) · Science Signaling

Circadian rhythm and melatoninReceptor Mechanisms and Signaling

Cited by 62

Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity

Gao, W., Liu, L., Huh, E., Gbahou, F., Cecon, E., Oshima, M., Houzé, L., Katsonis, P., Hegron, A., Fan, Z., et al. (2023) · Nature Metabolism

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 56