Elledge, Stephen J.

Sources of Error in Mammalian Genetic Screens

Sack, L. M., Davoli, T., Xu, Q., Li, M. Z., & Elledge, S. J. (2016) · G3 Genes|Genomes|Genetics

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 76

A genetic interaction analysis identifies cancer drivers that modify EGFR dependency

Liao, S., Davoli, T., Leng, Y., Li, M. Z., Xu, Q., & Elledge, S. J. (2017) · Genes & Development

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 67

A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach

Rousseaux, M. W. C., Vázquez-Vélez, G. E., Al-Ramahi, I., Jeong, H.-H., Bajić, A., Revelli, J.-P., Ye, H., Phan, E. T., Deger, J. M., Perez, A. M., et al. (2018) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 61

The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment

Siede, W., Allen, J. B., Elledge, S. J., & Friedberg, E. C. (1996) · Journal of Bacteriology

DNA Repair MechanismsFungal and yeast genetics research

Cited by 50

Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program

Mazzucco, A. E., Smogorzewska, A., Kang, C., Luo, J., Schlabach, M. R., Xu, Q., Patel, R., & Elledge, S. J. (2017) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 35

Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma

Nardone, C., Gao, J., Seo, H.-S., Mintseris, J., Ort, L., Yip, M. C. J., Negasi, M., Besschetnova, A. K., Kamitaki, N., Gygi, S. P., et al. (2025) · Molecular Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 22

Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma

Nardone, C., Gao, J., Seo, H.-S., Mintseris, J., Ort, L., Yip, M. C. J., Negasi, M., Besschetnova, A. K., Kamitaki, N., Gygi, S. P., et al. (2025) · Molecular Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 22

Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn

Liebhoff, A.-M., Venkataraman, T., Morgenlander, W. R., Na, M., Kula, T., Waugh, K., Morrison, C., Rewers, M., Longman, R., Round, J., et al. (2024) · Nature Communications

vaccines and immunoinformatics approachesBacteriophages and microbial interactions

Cited by 10

Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn

Liebhoff, A.-M., Venkataraman, T., Morgenlander, W. R., Na, M., Kula, T., Waugh, K., Morrison, C., Rewers, M., Longman, R., Round, J., et al. (2023) · Nature Communications

vaccines and immunoinformatics approachesBacteriophages and microbial interactions

Cited by 10