Carell, Thomas

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

Spruijt, C. G., Gnerlich, F., Smits, A. H., Pfaffeneder, T., Jansen, P. W. T. C., Bauer, C., Münzel, M., Wagner, M., Müller, M., Khan, F., et al. (2013) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 973

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

Thienpont, B., Steinbacher, J., Zhao, H., D’Anna, F., Kuchnio, A., Ploumakis, A., Ghesquière, B., Van Dyck, L., Boeckx, B., Schoonjans, L., et al. (2016) · Nature

Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism

Cited by 635

Thymine Dimerization in DNA Is an Ultrafast Photoreaction

Schreier, W. J., Schrader, T. E., Koller, F. O., Gilch, P., Crespo-Hernández, C. E., Swaminathan, V. N., Carell, T., Zinth, W., & Kohler, B. (2007) · Science

Photochemistry and Electron Transfer StudiesDNA and Nucleic Acid Chemistry

Cited by 550

Crystal Structure of a Photolyase Bound to a CPD-Like DNA Lesion After in Situ Repair

Mees, A., Klar, T., Gnau, P., Hennecke, U., Eker, A. P. M., Carell, T., & Essen, L.-O. (2004) · Science

DNA Repair MechanismsEnzyme Structure and Function

Cited by 386

Unified Prebiotically Plausible Synthesis of Pyrimidine and Purine RNA Ribonucleotides

Becker, S., Feldmann, J., Wiedemann, S., Okamura, H., Schneider, C., Iwan, K., Crisp, A., Rossa, M., Amatov, T., & Carell, T. (2019) · Science

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 306

Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals

Shachar, S., Ziv, O., Avkin, S., Adar, S., Wittschieben, J., Reißner, T., Chaney, S., Friedberg, E. C., Wang, Z., Carell, T., et al. (2009) · The EMBO Journal

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 284

A High-Yielding, Strictly Regioselective Prebiotic Purine Nucleoside Formation Pathway

Becker, S., Thoma, I., Deutsch, A., Gehrke, T., Mayer, P., Zipse, H., & Carell, T. (2016) · Science

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 238

When Did Life Likely Emerge on Earth in an RNA‐First Process?

Benner, S. A., Bell, E. A., Biondi, E., Brasser, R., Carell, T., Kim, H., Mojzsis, S. J., Omran, A., Pasek, M. A., & Trail, D. (2020) · ChemSystemsChem

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 162

Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis

Becker, S., Schneider, C., Okamura, H., Crisp, A., Amatov, T., Dejmek, M., & Carell, T. (2018) · Nature Communications

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 153

TET3 Is Recruited by REST for Context-Specific Hydroxymethylation and Induction of Gene Expression

Perera, A., Eisen, D., Wagner, M., Laube, S. K., Künzel, A. F., Koch, S., Steinbacher, J., Schulze, E., Splith, V., Mittermeier, N., et al. (2015) · Cell Reports

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 145

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

Hendel, A., Krijger, P. H. L., Diamant, N., Goren, Z., Langerak, P., Kim, J., Reißner, T., Lee, K.-Y., Geacintov, N. E., Carell, T., et al. (2011) · PLoS Genetics

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 132

Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

Walmacq, C., Cheung, A. C. M., Kireeva, M. L., Lubkowska, L., Ye, C., Gotte, D., Strathern, J. N., Carell, T., Cramer, P., & Kashlev, M. (2012) · Molecular Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 124

DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity

Diamant, N., Hendel, A., Vered, I., Carell, T., Reißner, T., de Wind, N., Geacinov, N., & Livneh, Z. (2012) · Nucleic Acids Research

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 109

Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin

Ziv, O., Zeisel, A., Mirlas-Neisberg, N., Swain, U., Nevo, R., Ben-Chetrit, N., Martelli, M. P., Rossi, R., Schiesser, S., Canman, C. E., et al. (2014) · Nature Communications

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 59

Discovery and Synthesis of New UV-Induced Intrastrand C(4−8)G and G(8−4)C Photolesions

Münzel, M., Szeibert, C., Glas, A. F., Globisch, D., & Carell, T. (2011) · Journal of the American Chemical Society

DNA and Nucleic Acid ChemistryDNA Repair Mechanisms

Cited by 28