Arlotta, Paola

Cell diversity and network dynamics in photosensitive human brain organoids

Quadrato, G., Nguyen, T., Macosko, E. Z., Sherwood, J. L., Min Yang, S., Berger, D. R., Maria, N., Scholvin, J., Goldman, M., Kinney, J. P., et al. (2017) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 1,321

Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2

Stickels, R. R., Murray, E., Kumar, P., Li, J., Marshall, J. L., Di Bella, D. J., Arlotta, P., Macosko, E. Z., & Chen, F. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsRNA Research and Splicing

Cited by 1,295

Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

Velasco, S., Kedaigle, A. J., Simmons, S. K., Nash, A., Rocha, M., Quadrato, G., Paulsen, B., Nguyen, L., Adiconis, X., Regev, A., et al. (2019) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 1,094

Distinct Profiles of Myelin Distribution Along Single Axons of Pyramidal Neurons in the Neocortex

Tomassy, G. S., Berger, D. R., Chen, H.-H., Kasthuri, N., Hayworth, K. J., Vercelli, A., Seung, H. S., Lichtman, J. W., & Arlotta, P. (2014) · Science

Neuroscience and Neuropharmacology ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 600

Molecular logic of cellular diversification in the mouse cerebral cortex

Di Bella, D. J., Habibi, E., Stickels, R. R., Scalia, G., Brown, J., Yadollahpour, P., Yang, S. M., Abbate, C., Biancalani, T., Macosko, E. Z., et al. (2021) · Nature

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 464

Autism genes converge on asynchronous development of shared neuron classes

Paulsen, B., Velasco, S., Kedaigle, A. J., Pigoni, M., Quadrato, G., Deo, A. J., Adiconis, X., Uzquiano, A., Sartore, R., Yang, S. M., et al. (2022) · Nature

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 439

Generating Neuronal Diversity in the Mammalian Cerebral Cortex

Lodato, S., & Arlotta, P. (2015) · Annual Review of Cell and Developmental Biology

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 389

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes

Jin, X., Simmons, S. K., Guo, A., Shetty, A. S., Ko, M., Nguyen, L., Jokhi, V., Robinson, E., Oyler, P., Curry, N., et al. (2020) · Science

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 317

The promises and challenges of human brain organoids as models of neuropsychiatric disease

Quadrato, G., Brown, J., & Arlotta, P. (2016) · Nature Medicine

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 304

Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex

Lodato, S., Rouaux, C., Quast, K. B., Jantrachotechatchawan, C., Studer, M., Hensch, T. K., & Arlotta, P. (2011) · Neuron

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 244

Genetic dissection of the glutamatergic neuron system in cerebral cortex

Matho, K. S., Huilgol, D., Galbavy, W., He, M., Kim, G., An, X., Lu, J., Wu, P., Di Bella, D. J., Shetty, A. S., et al. (2021) · Nature

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 155

Diversity Matters: A Revised Guide to Myelination

Tomassy, G. S., Dershowitz, L. B., & Arlotta, P. (2016) · Trends in Cell Biology

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 115

Loss of COUP-TFI Alters the Balance between Caudal Ganglionic Eminence- and Medial Ganglionic Eminence-Derived Cortical Interneurons and Results in Resistance to Epilepsy

Lodato, S., Tomassy, G. S., De Leonibus, E., Uzcategui, Y. G., Andolfi, G., Armentano, M., Touzot, A., Gaztelu, J. M., Arlotta, P., Menendez de la Prida, L., et al. (2011) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsEpilepsy research and treatment

Cited by 112

Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons

Ye, Z., Mostajo-Radji, M. A., Brown, J. R., Rouaux, C., Tomassy, G. S., Hensch, T. K., & Arlotta, P. (2015) · Neuron

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 73

Glioblastoma-cortical organoids recapitulate cell state heterogeneity and intercellular transfer

Mangena, V., Chanoch-Myers, R., Sartore, R., Paulsen, B., Gritsch, S., Weisman, H., Hara, T., Breakefield, X. O., Breyne, K., Regev, A., et al. (2025) · Cancer Discovery

Glioma Diagnosis and TreatmentExtracellular vesicles in disease

Cited by 49

Molecular Logic of Cellular Diversification in the Mammalian Cerebral Cortex

Di Bella, D. J., Habibi, E., Yang, S.-M., Stickels, R. R., Brown, J., Yadollahpour, P., Chen, F., Macosko, E. Z., Regev, A., & Arlotta, P. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 20

Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex

Matho, K. S., Huilgol, D., Galbavy, W., He, M., Kim, G., An, X., Lu, J., Wu, P., Di Bella, D. J., Shetty, A. S., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 20