Beerman, Isabel

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

Pang, W. W., Price, E. A., Sahoo, D., Beerman, I., Maloney, W. J., Rossi, D. J., Schrier, S. L., & Weissman, I. L. (2011) · Proceedings of the National Academy of Sciences

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 991

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Beerman, I., Bhattacharya, D., Zandi, S., Sigvardsson, M., Weissman, I. L., Bryder, D., & Rossi, D. J. (2010) · Proceedings of the National Academy of Sciences

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 711

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging

Beerman, I., Bock, C., Garrison, B. S., Smith, Z. D., Gu, H., Meissner, A., & Rossi, D. J. (2013) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 485

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle

Beerman, I., Seita, J., Inlay, M. A., Weissman, I. L., & Rossi, D. J. (2014) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

Cited by 445

Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress

Scaramozza, A., Park, D., Kollu, S., Beerman, I., Sun, X., Rossi, D. J., Lin, C. P., Scadden, D. T., Crist, C., & Brack, A. S. (2019) · Cell Stem Cell

Muscle Physiology and DisordersMesenchymal stem cell research

Cited by 93

Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage

Gutierrez-Martinez, P., Hogdal, L., Nagai, M., Kruta, M., Singh, R., Sarosiek, K., Nussenzweig, A., Beerman, I., Letai, A., & Rossi, D. J. (2018) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

Cited by 60

DNA damage in aging, the stem cell perspective

McNeely, T., Leone, M., Yanai, H., & Beerman, I. (2020) · Human Genetics

Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms

Cited by 52

NAD+ augmentation with nicotinamide riboside improves lymphoid potential of Atm−/− and old mice HSCs

Zong, L., Tanaka-Yano, M., Park, B., Yanai, H., Turhan, F. T., Croteau, D. L., Tian, J., Fang, E. F., Bohr, V. A., & Beerman, I. (2021) · npj Aging and Mechanisms of Disease

Sirtuins and Resveratrol in MedicineHematopoietic Stem Cell Transplantation

Cited by 22

Short-term senolytic treatment: a paradigm to promote fracture repair during aging

Beerman, I., Basisty, N., & de Cabo, R. (2022) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceBone Metabolism and Diseases

Cited by 15

Proliferation: Driver of HSC aging phenotypes?

Yanai, H., & Beerman, I. (2020) · Mechanisms of Ageing and Development

Hematopoietic Stem Cell TransplantationGenetics, Aging, and Longevity in Model Organisms

Cited by 9