Smith, Douglas H.

Axonal pathology in traumatic brain injury

Johnson, V. E., Stewart, W., & Smith, D. H. (2013) · Experimental Neurology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 1,273

Inflammation and white matter degeneration persist for years after a single traumatic brain injury

Johnson, V. E., Stewart, J. E., Begbie, F. D., Trojanowski, J. Q., Smith, D. H., & Stewart, W. (2013) · Brain

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,045

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

Smith, D. H., Johnson, V. E., & Stewart, W. (2013) · Nature Reviews Neurology

Traumatic Brain Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 699

Widespread tau and amyloid-beta pathology many years after a single traumatic brain injury in humans

Johnson, V. E., Stewart, W., & Smith, D. H. (2012) · Brain Pathology

Traumatic Brain Injury ResearchAlzheimer's disease research and treatments

Cited by 620

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

Johnson, V. E., Stewart, W., & Smith, D. H. (2010) · Nature Reviews Neuroscience

Alzheimer's disease research and treatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 587

A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effects

SMITH, D. H., SOARES, H. D., PIERCE, J. S., PERLMAN, K. G., SAATMAN, K. E., MEANEY, D. F., DIXON, C. E., & McINTOSH, T. K. (1995) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 451

Progressive atrophy and neuron death for one year following brain trauma in the rat

Smith, D. H., Chen, X.-H., Pierce, J. E. S., Wolf, J. A., Trojanowski, J. Q., Graham, D. I., & McIntosh, T. K. (1997) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 440

Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats

Pierce, J. E. S., Smith, D. H., Trojanowski, J. Q., & McIntosh, T. K. (1998) · Neuroscience

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 385

Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury

Soares, H., Hicks, R., Smith, D., & McIntosh, T. (1995) · The Journal of Neuroscience

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 379

Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans

Uryu, K., Chen, X.-H., Martinez, D., Browne, K. D., Johnson, V. E., Graham, D. I., Lee, V. M.-Y., Trojanowski, J. Q., & Smith, D. H. (2007) · Experimental Neurology

Traumatic Brain Injury and Neurovascular DisturbancesAlzheimer's disease research and treatments

Cited by 360

Long-Term Accumulation of Amyloid-β, β-Secretase, Presenilin-1, and Caspase-3 in Damaged Axons Following Brain Trauma

Chen, X.-H., Siman, R., Iwata, A., Meaney, D. F., Trojanowski, J. Q., & Smith, D. H. (2004) · The American Journal of Pathology

Alzheimer's disease research and treatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 271

A Lack of Amyloid β Plaques Despite Persistent Accumulation of Amyloid β in Axons of Long‐Term Survivors of Traumatic Brain Injury

Chen, X., Johnson, V. E., Uryu, K., Trojanowski, J. Q., & Smith, D. H. (2009) · Brain Pathology

Alzheimer's disease research and treatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 267

Accumulation of Amyloid β and Tau and the Formation of Neurofilament Inclusions Following Diffuse Brain Injury in the Pig

Smith, D. H., Chen, X.-H., Nonaka, M., Trojanowski, J. Q., Lee, V.-Y., Saatman, K. E., Leoni, M. J., Xu, B.-N., Wolf, J. A., & Meaney, D. F. (1999) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 260

Biomechanical Analysis of Experimental Diffuse Axonal Injury

MEANEY, D. F., SMITH, D. H., SHREIBER, D. I., BAIN, A. C., MILLER, R. T., ROSS, D. T., & GENNARELLI, T. A. (1995) · Journal of Neurotrauma

Automotive and Human Injury BiomechanicsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 254

Mild traumatic brain injury and diffuse axonal injury in swine

Browne, K. D., Chen, X.-H., Meaney, D. F., & Smith, D. H. (2011) · Journal of Neurotrauma

Traumatic Brain Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 248

Insulin-like Growth Factor-1 (IGF-1) Improves both Neurological Motor and Cognitive Outcome Following Experimental Brain Injury

Saatman, K. E., Contreras, P. C., Smith, D. H., Raghupathi, R., McDermott, K. L., Fernandez, S. C., Sanderson, K. L., Voddi, M., & McIntosh, T. K. (1997) · Experimental Neurology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 185

Prolonged Activation of NF-κB Following Traumatic Brain Injury in Rats

NONAKA, M., CHEN, X.-H., PIERCE, J. E. S., LEONI, M. J., McINTOSH, T. K., WOLF, J. A., & SMITH, D. H. (1999) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesNF-κB Signaling Pathways

Cited by 176

Chronic traumatic encephalopathy - confusion and controversies

Smith, D. H., Johnson, V. E., Trojanowski, J. Q., & Stewart, W. (2019) · Nature Reviews Neurology

Traumatic Brain Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 166

Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players

Lee, E. B., Kinch, K., Johnson, V. E., Trojanowski, J. Q., Smith, D. H., & Stewart, W. (2019) · Acta Neuropathologica

Traumatic Brain Injury ResearchDementia and Cognitive Impairment Research

Cited by 157

Brain Trauma Induces Massive Hippocampal Neuron Death Linked to a Surge in β-Amyloid Levels in Mice Overexpressing Mutant Amyloid Precursor Protein

Smith, D. H., Nakamura, M., McIntosh, T. K., Wang, J., Rodríguez, A., Chen, X.-H., Raghupathi, R., Saatman, K. E., Clemens, J., Schmidt, M. L., et al. (1998) · The American Journal of Pathology

Alzheimer's disease research and treatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 143

A porcine model of traumatic brain injury via head rotational acceleration

Cullen, D. K., Harris, J. P., Browne, K. D., Wolf, J. A., Duda, J. E., Meaney, D. F., Margulies, S. S., & Smith, D. H. (2016) · Methods in Molecular Biology

Automotive and Human Injury BiomechanicsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 142

Induction of a transmissible tau pathology by traumatic brain injury

Zanier, E. R., Bertani, I., Sammali, E., Pischiutta, F., Chiaravalloti, M. A., Vegliante, G., Masone, A., Corbelli, A., Smith, D. H., Menon, D. K., et al. (2018) · Brain

Alzheimer's disease research and treatmentsTraumatic Brain Injury Research

Cited by 136

Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury

Dollé, J.-P., Jaye, A., Anderson, S. A., Ahmadzadeh, H., Shenoy, V. B., & Smith, D. H. (2018) · Experimental Neurology

Traumatic Brain Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 128

Biomarkers in Spinal Cord Injury: Prognostic Insights and Future Potentials

Albayar, A. A., Roche, A., Swiatkowski, P., Antar, S., Ouda, N., Emara, E., Smith, D. H., Ozturk, A. K., & Awad, B. I. (2019) · Frontiers in Neurology

Spinal Cord Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 108