Bakhoum, Samuel F.

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

Genovese, G., Kähler, A. K., Handsaker, R. E., Lindberg, J., Rose, S. A., Bakhoum, S. F., Chambert, K., Mick, E., Neale, B. M., Fromer, M., et al. (2014) · New England Journal of Medicine

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 3,531

Chromosomal instability drives metastasis through a cytosolic DNA response

Bakhoum, S. F., Ngo, B., Laughney, A. M., Cavallo, J.-A., Murphy, C. J., Ly, P., Shah, P., Sriram, R. K., Watkins, T. B. K., Taunk, N. K., et al. (2018) · Nature

interferon and immune responsesMicrotubule and mitosis dynamics

Cited by 1,593

The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer

Kwon, J., & Bakhoum, S. F. (2020) · Cancer Discovery

interferon and immune responsesCancer Immunotherapy and Biomarkers

Cited by 1,293

Genome stability is ensured by temporal control of kinetochore–microtubule dynamics

Bakhoum, S. F., Thompson, S. L., Manning, A. L., & Compton, D. A. (2009) · Nature Cell Biology

Microtubule and mitosis dynamicsDNA Repair Mechanisms

Cited by 453

Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations

Loh, P.-R., Genovese, G., Handsaker, R. E., Finucane, H. K., Reshef, Y. A., Palamara, P. F., Birmann, B. M., Talkowski, M. E., Bakhoum, S. F., McCarroll, S. A., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 423

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Li, J., Duran, M. A., Dhanota, N., Chatila, W. K., Bettigole, S. E., Kwon, J., Sriram, R. K., Humphries, M. P., Salto-Tellez, M., James, J. A., et al. (2021) · Cancer Discovery

Adenosine and Purinergic SignalingCancer Immunotherapy and Biomarkers

Cited by 312

The mitotic origin of chromosomal instability

Bakhoum, S. F., Silkworth, W. T., Nardi, I. K., Nicholson, J. M., Compton, D. A., & Cimini, D. (2014) · Current Biology

Microtubule and mitosis dynamicsDNA Repair Mechanisms

Cited by 142

Numerical chromosomal instability mediates susceptibility to radiation treatment

Bakhoum, S. F., Kabeche, L., Wood, M. D., Laucius, C. D., Qu, D., Laughney, A. M., Reynolds, G. E., Louie, R. J., Phillips, J., Chan, D. A., et al. (2015) · Nature Communications

Effects of Radiation ExposureMicrotubule and mitosis dynamics

Cited by 95