Parton, Robert G.

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

Takasato, M., Er, P. X., Chiu, H. S., Maier, B., Baillie, G. J., Ferguson, C., Parton, R. G., Wolvetang, E. J., Roost, M. S., Chuva de Sousa Lopes, S. M., et al. (2015) · Nature

Renal and related cancersPluripotent Stem Cells Research

Cited by 1,627

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K., & Zerial, M. (1990) · Cell

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,166

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

Stenmark, H., Parton, R. G., Steele‐Mortimer, O., Lütcke, A., Gruenberg, J., & Zerial, M. (1994) · The EMBO Journal

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 968

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

Kobayashi, T., Stang, E., Fang, K. S., de Moerloose, P., Parton, R. G., & Gruenberg, J. (1998) · Nature

Cellular transport and secretionSystemic Lupus Erythematosus Research

Cited by 787

Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization

Matsuo, H., Chevallier, J., Mayran, N., Le Blanc, I., Ferguson, C., Fauré, J., Blanc, N. S., Matile, S., Dubochet, J., Sadoul, R., et al. (2004) · Science

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 705

Clathrin-independent pathways of endocytosis

Mayor, S., Parton, R. G., & Donaldson, J. G. (2014) · Cold Spring Harbor Perspectives in Biology

Cellular transport and secretionCaveolin-1 and cellular processes

Cited by 525

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

Bosch, M., Sánchez-Álvarez, M., Fajardo, A., Kapetanovic, R., Steiner, B., Dutra, F., Moreira, L., López, J. A., Campo, R., Marí, M., et al. (2020) · Science

Lipid metabolism and biosynthesisImmune Response and Inflammation

Cited by 480

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Mills, R. J., Titmarsh, D. M., Koenig, X., Parker, B. L., Ryall, J. G., Quaife-Ryan, G. A., Voges, H. K., Hodson, M. P., Ferguson, C., Drowley, L., et al. (2017) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 478

Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles

Kirkham, M., Fujita, A., Chadda, R., Nixon, S. J., Kurzchalia, T. V., Sharma, D. K., Pagano, R. E., Hancock, J. F., Mayor, S., & Parton, R. G. (2005) · The Journal of Cell Biology

Caveolin-1 and cellular processesCellular transport and secretion

Cited by 439

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

Howes, M. T., Kirkham, M., Riches, J., Cortese, K., Walser, P. J., Simpson, F., Hill, M. M., Jones, A., Lundmark, R., Lindsay, M. R., et al. (2010) · Journal of Cell Biology

Cellular transport and secretionCaveolin-1 and cellular processes

Cited by 303

Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission

Palmer, C. S., Elgass, K. D., Parton, R. G., Osellame, L. D., Stojanovski, D., & Ryan, M. T. (2013) · Journal of Biological Chemistry

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 301

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

Wu, S. K., Gomez, G. A., Michael, M., Verma, S., Cox, H. L., Lefevre, J. G., Parton, R. G., Hamilton, N. A., Neufeld, Z., & Yap, A. S. (2014) · Nature Cell Biology

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

Cited by 230

Cavin family proteins and the assembly of caveolae

Kovtun, O., Tillu, V. A., Ariotti, N., Parton, R. G., & Collins, B. M. (2015) · Journal of Cell Science

Caveolin-1 and cellular processesLipid Membrane Structure and Behavior

Cited by 230

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

Morén, B., Shah, C., Howes, M. T., Schieber, N. L., McMahon, H. T., Parton, R. G., Daumke, O., & Lundmark, R. (2012) · Molecular Biology of the Cell

Caveolin-1 and cellular processesCellular transport and secretion

Cited by 207

Development of a human cardiac organoid injury model reveals innate regenerative potential

Voges, H. K., Mills, R. J., Elliott, D. A., Parton, R. G., Porrello, E. R., & Hudson, J. E. (2017) · Development

Congenital heart defects researchTissue Engineering and Regenerative Medicine

Cited by 196

pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells

Parton, R. G., Dotti, C. G., Bacallao, R., Kurtz, I., Simons, K., & Prydz, K. (1991) · The Journal of cell biology

Cellular transport and secretionMicrotubule and mitosis dynamics

Cited by 115

Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

Low, J. T., Mitchell, J. M., Do, O. H., Bax, J., Rawlings, A., Zavortink, M., Morgan, G., Parton, R. G., Gaisano, H. Y., & Thorn, P. (2013) · Diabetologia

Pancreatic function and diabetesCellular transport and secretion

Cited by 43

Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1‐SV2 plasma membrane nanocluster for synaptic vesicle entry

Joensuu, M., Syed, P., Saber, S. H., Lanoue, V., Wallis, T. P., Rae, J., Blum, A., Gormal, R. S., Small, C., Sanders, S., et al. (2023) · The EMBO Journal

Botulinum Toxin and Related Neurological DisordersCellular transport and secretion

Cited by 34

Synaptotagmin 1 mediates toxicity of botulinum neurotoxin type A

Joensuu, M., Lanoue, V., Syed, P., Wallis, T. P., Rae, J., Blum, A., Gormal, R., Small, C., Sanders, S., Jiang, A., et al. (2022) · The EMBO Journal

Botulinum Toxin and Related Neurological DisordersCellular transport and secretion

Cited by 34

Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli

Stocks, C. J., von Pein, J. B., Curson, J. E. B., Rae, J., Phan, M.-D., Foo, D., Bokil, N. J., Kambe, T., Peters, K. M., Parton, R. G., et al. (2021) · Journal of Leukocyte Biology

Immune Response and InflammationTrace Elements in Health

Cited by 28