Frye, Mark A.

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, Stahl, E. A., BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., et al. (2019) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,519

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

Pacchiarotti, I., Bond, D. J., Baldessarini, R. J., Nolen, W. A., Grunze, H., Licht, R. W., Post, R. M., Berk, M., Goodwin, G. M., Sachs, G. S., et al. (2013) · American Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 770

Screening for Bipolar Disorder in the Community

Hirschfeld, R. M. A., Calabrese, J. R., Weissman, M. M., Reed, M., Davies, M. A., Frye, M. A., Keck, P. E., Lewis, L., McElroy, S. L., McNulty, J. P., et al. (2003) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentMental Health Treatment and Access

Cited by 674

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., Aliev, F., Bacanu, S.-A., Batzler, A., et al. (2018) · Nature Neuroscience

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 632

A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders

Sanacora, G., Frye, M. A., McDonald, W., Mathew, S. J., Turner, M. S., Schatzberg, A. F., Summergrad, P., Nemeroff, C. B., & for the American Psychiatric Association (APA) Council of Research Task Force on Novel Biomarkers and Treatments (2017) · JAMA Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 576

A Placebo-Controlled Study of Lamotrigine and Gabapentin Monotherapy in Refractory Mood Disorders

Frye, M. A., Ketter, T. A., Kimbrell, T. A., Dunn, R. T., Speer, A. M., Osuch, E. A., Luckenbaugh, D. A., Corá-Locatelli, G., Leverich, G. S., & Post, R. M. (2000) · Journal of Clinical Psychopharmacology

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 446

Morbidity in 258 Bipolar Outpatients Followed for 1 Year With Daily Prospective Ratings on the NIMH Life Chart Method

Post, R. M., Denicoff, K. D., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., Rush, A. J., Keck, P. E., McElroy, S. L., Luckenbaugh, D. A., et al. (2003) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 418

Can bipolar disorder be viewed as a multi-system inflammatory disease?

Leboyer, M., Soreca, I., Scott, J., Frye, M., Henry, C., Tamouza, R., & Kupfer, D. J. (2012) · Journal of Affective Disorders

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 417

Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder 1

Kupka, R. W., Altshuler, L. L., Nolen, W. A., Suppes, T., Luckenbaugh, D. A., Leverich, G. S., Frye, M. A., Keck, P. E., McElroy, S. L., Grunze, H., et al. (2007) · Bipolar Disorders

Bipolar Disorder and TreatmentMental Health Research Topics

Cited by 397

Early-Onset Bipolar Disorder and Treatment Delay Are Risk Factors for Poor Outcome in Adulthood

Post, R. M., Leverich, G. S., Kupka, R. W., Keck, P. E., McElroy, S. L., Altshuler, L. L., Frye, M. A., Luckenbaugh, D. A., Rowe, M., Grunze, H., et al. (2010) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 360

Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline

Post, R. M., Altshuler, L. L., Leverich, G. S., Frye, M. A., Nolen, W. A., Kupka, R. W., Suppes, T., McElroy, S., Keck, P. E., Denicoff, K. D., et al. (2006) · British Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 350

Impact of Antidepressant Discontinuation After Acute Bipolar Depression Remission on Rates of Depressive Relapse at 1-Year Follow-Up

Altshuler, L., Suppes, T., Black, D., Nolen, W. A., Keck, P. E., Frye, M. A., McElroy, S., Kupka, R., Grunze, H., Walden, J., et al. (2003) · American Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 287

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 270

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Hatoum, A. S., Colbert, S. M. C., Johnson, E. C., Huggett, S. B., Deak, J. D., Pathak, G. A., Jennings, M. V., Paul, S. E., Karcher, N. R., Hansen, I., et al. (2023) · Nature Mental Health

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 241

Biomarkers in bipolar disorder: a positional paper from the international society for bipolar disorders biomarkers task force.

Frey, B. N., Andreazza, A. C., Houenou, J., Jamain, S., Goldstein, B. I., Frye, M. A., Leboyer, M., Berk, M., Malhi, G. S., Lopez-Jaramillo, C., et al. (2013) · Australian & New Zealand Journal of Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 234

Double-Blind, Randomized, Placebo-Controlled Trials of Ethyl-Eicosapentanoate in the Treatment of Bipolar Depression and Rapid Cycling Bipolar Disorder

Keck, P. E., Mintz, J., McElroy, S. L., Freeman, M. P., Suppes, T., Frye, M. A., Altshuler, L. L., Kupka, R., Nolen, W. A., Leverich, G. S., et al. (2006) · Biological Psychiatry

Bipolar Disorder and TreatmentFatty Acid Research and Health

Cited by 234

Augmentation strategies for treatment resistant major depression: A systematic review and network meta-analysis

Nuñez, N. A., Joseph, B., Pahwa, M., Kumar, R., Resendez, M. G., Prokop, L. J., Veldic, M., Seshadri, A., Biernacka, J. M., Frye, M. A., et al. (2022) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 215

Mixed Hypomania in 908 Patients With Bipolar Disorder Evaluated Prospectively in the Stanley Foundation Bipolar Treatment Network: A Sex-Specific Phenomenon

Suppes, T., Mintz, J., McElroy, S. L., Altshuler, L. L., Kupka, R. W., Frye, M. A., Keck, P. E., Nolen, W. A., Leverich, G. S., Grunze, H., et al. (2005) · Archives of General Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 209

Principal components of the Beck Depression inventory and regional cerebral metabolism in unipolar and bipolar depression

Dunn, R. T., Kimbrell, T. A., Ketter, T. A., Frye, M. A., Willis, M. W., Luckenbaugh, D. A., & Post, R. M. (2002) · Biological Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 184

Subsyndromal Depression Is Associated With Functional Impairment in Patients With Bipolar Disorder

Altshuler, L. L., Gitlin, M. J., Mintz, J., Leight, K. L., & Frye, M. A. (2002) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 174

The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management

McIntyre, R. S., Alda, M., Baldessarini, R. J., Bauer, M., Berk, M., Correll, C. U., Fagiolini, A., Fountoulakis, K., Frye, M. A., Grunze, H., et al. (2022) · World Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 171

Prevalence and correlates of eating disorders in 875 patients with bipolar disorder

McElroy, S. L., Frye, M. A., Hellemann, G., Altshuler, L., Leverich, G. S., Suppes, T., Keck, P. E., Nolen, W. A., Kupka, R., & Post, R. M. (2011) · Journal of Affective Disorders

Eating Disorders and BehaviorsBipolar Disorder and Treatment

Cited by 162