Shirihai, Orian S.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 3,082

Pancreatic cancers require autophagy for tumor growth

Yang, S., Wang, X., Contino, G., Liesa, M., Sahin, E., Ying, H., Bause, A., Li, Y., Stommel, J. M., Dell'Antonio, G., et al. (2011) · Genes & Development

Autophagy in Disease and TherapyPancreatic and Hepatic Oncology Research

Cited by 1,498

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

Liesa, M., & Shirihai, O. S. (2013) · Cell Metabolism

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,341

Telomere dysfunction induces metabolic and mitochondrial compromise

Sahin, E., Colla, S., Liesa, M., Moslehi, J., Müller, F. L., Guo, M., Cooper, M., Kotton, D., Fabian, A. J., Walkey, C., et al. (2011) · Nature

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,319

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

Zhong, L., D'Urso, A., Toiber, D., Sebastian, C., Henry, R. E., Vadysirisack, D. D., Guimaraes, A., Marinelli, B., Wikstrom, J. D., Nir, T., et al. (2010) · Cell

Sirtuins and Resveratrol in MedicineMetabolism, Diabetes, and Cancer

Cited by 1,001

The Interplay Between Mitochondrial Dynamics and Mitophagy

Twig, G., & Shirihai, O. S. (2011) · Antioxidants & Redox Signaling

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 778

Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

Shenouda, S. M., Widlansky, M. E., Chen, K., Xu, G., Holbrook, M., Tabit, C. E., Hamburg, N. M., Frame, A. A., Caiano, T. L., Kluge, M. A., et al. (2011) · Circulation

Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects

Cited by 570

Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis

Molina, A. J. A., Wikstrom, J. D., Stiles, L., Las, G., Mohamed, H., Elorza, A., Walzer, G., Twig, G., Katz, S., Corkey, B. E., et al. (2009) · Diabetes

Mitochondrial Function and PathologyPancreatic function and diabetes

Cited by 381

Mitochondria Bound to Lipid Droplets: Where Mitochondrial Dynamics Regulate Lipid Storage and Utilization

Benador, I. Y., Veliova, M., Liesa, M., & Shirihai, O. S. (2019) · Cell Metabolism

Mitochondrial Function and PathologyLipid metabolism and biosynthesis

Cited by 363

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

Kottakis, F., Nicolay, B. N., Roumane, A., Karnik, R., Gu, H., Nagle, J. M., Boukhali, M., Hayward, M. C., Li, Y. Y., Chen, T., et al. (2016) · Nature

Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism

Cited by 348

How mitochondrial dynamism orchestrates mitophagy

Shirihai, O. S., Song, M., & Dorn, G. W. (2015) · Circulation Research

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 311

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Danial, N. N., Walensky, L. D., Zhang, C.-Y., Choi, C. S., Fisher, J. K., Molina, A. J. A., Datta, S. R., Pitter, K. L., Bird, G. H., Wikstrom, J. D., et al. (2008) · Nature Medicine

Pancreatic function and diabetesCell death mechanisms and regulation

Cited by 307

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

Momcilovic, M., Jones, A., Bailey, S. T., Waldmann, C. M., Li, R., Lee, J. T., Abdelhady, G., Gomez, A., Holloway, T., Schmid, E., et al. (2019) · Nature

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 214

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency

Rodríguez‐Nuevo, A., Díaz‐Ramos, A., Noguera, E., Díaz‐Sáez, F., Duran, X., Muñoz, J. P., Romero, M., Plana, N., Sebastián, D., Tezze, C., et al. (2018) · The EMBO Journal

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 207

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells

Ferdaoussi, M., Dai, X., Jensen, M. V., Wang, R., Peterson, B. S., Huang, C., Ilkayeva, O., Smith, N., Miller, N., Hajmrle, C., et al. (2015) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 169

Cell Culture Models of Fatty Acid Overload: Problems and Solutions

Alsabeeh, N., Chausse, B., Kakimoto, P. A., Kowaltowski, A. J., & Shirihai, O. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Lipid metabolism and biosynthesisDiet, Metabolism, and Disease

Cited by 167

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

Robson-Doucette, C. A., Sultan, S., Allister, E. M., Wikstrom, J. D., Koshkin, V., Bhattacharjee, A., Prentice, K. J., Sereda, S. B., Shirihai, O. S., & Wheeler, M. B. (2011) · Diabetes

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 136

The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle

Moore, T. M., Zhou, Z., Cohn, W., Norheim, F., Lin, A. J., Kalajian, N., Strumwasser, A. R., Cory, K., Whitney, K., Ho, T., et al. (2019) · Molecular Metabolism

Mitochondrial Function and PathologyCardiovascular and exercise physiology

Cited by 131

Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity

Acín-Pérez, R., Iborra, S., Martí-Mateos, Y., Cook, E. C. L., Conde-Garrosa, R., Petcherski, A., Muñoz, M. D. M., Martínez de Mena, R., Krishnan, K. C., Jiménez, C., et al. (2020) · Nature Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 83

Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in Male mice

Guo, W., Wong, S., Li, M., Liang, W., Liesa, M., Serra, C., Jasuja, R., Bartke, A., Kirkland, J. L., Shirihai, O., et al. (2012) · PLoS ONE

Hormonal and reproductive studiesMuscle Physiology and Disorders

Cited by 59

Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells

Liu, S., Okada, T., Assmann, A., Soto, J., Liew, C. W., Bugger, H., Shirihai, O. S., Abel, E. D., & Kulkarni, R. N. (2009) · PLoS ONE

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 58

Proteinuria causes dysfunctional autophagy in the proximal tubule

Nolin, A. C., Mulhern, R. M., Panchenko, M. V., Pisarek-Horowitz, A., Wang, Z., Shirihai, O., Borkan, S. C., & Havasi, A. (2016) · American Journal of Physiology-Renal Physiology

Autophagy in Disease and TherapyRenal Diseases and Glomerulopathies

Cited by 58