Helmann, John D.

Metal homeostasis and resistance in bacteria

Chandrangsu, P., Rensing, C., & Helmann, J. D. (2017) · Nature Reviews Microbiology

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 812

The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation

Lee, J.-W., & Helmann, J. D. (2006) · Nature

Redox biology and oxidative stressBacterial Genetics and Biotechnology

Cited by 547

Functional specialization within the Fur family of metalloregulators

Lee, J.-W., & Helmann, J. D. (2007) · BioMetals

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 432

Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins

Que, Q., & Helmann, J. D. (2000) · Molecular Microbiology

Bacterial Genetics and BiotechnologyHeavy Metal Exposure and Toxicity

Cited by 282

Recognition of DNA by Fur: a Reinterpretation of the Fur Box Consensus Sequence

Baichoo, N., & Helmann, J. D. (2002) · Journal of Bacteriology

Bacterial Genetics and BiotechnologyGenomics and Chromatin Dynamics

Cited by 282

Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon

Baichoo, N., Wang, T., Ye, R., & Helmann, J. D. (2002) · Molecular Microbiology

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 250

Elemental Economy

Merchant, S. S., & Helmann, J. D. (2012) · Advances in Microbial Physiology

Marine Plankton and BiogeochemistryMicrobial Community Ecology and Physiology

Cited by 246

The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins

Gaballa, A., Antelmann, H., Aguilar, C., Khakh, S. K., Song, K.-B., Smaldone, G. T., & Helmann, J. D. (2008) · Proceedings of the National Academy of Sciences

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 232

Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions

Chen, L., Keramati, L., & Helmann, J. D. (1995) · Proceedings of the National Academy of Sciences

Bacterial Genetics and BiotechnologyRedox biology and oxidative stress

Cited by 229

Specificity of Metal Sensing: Iron and Manganese Homeostasis in Bacillus subtilis

Helmann, J. D. (2014) · Journal of Biological Chemistry

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 153

Peroxide Stress Elicits Adaptive Changes in Bacterial Metal Ion Homeostasis

Faulkner, M. J., & Helmann, J. D. (2011) · Antioxidants & Redox Signaling

Bacterial Genetics and BiotechnologyRedox biology and oxidative stress

Cited by 151

Mn2+-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches

Price, I. R., Gaballa, A., Ding, F., Helmann, J. D., & Ke, A. (2015) · Molecular Cell

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 136

A novel DNA modification by sulphur

Zhou, X., He, X., Liang, J., Li, A., Xu, T., Kieser, T., Helmann, J. D., & Deng, Z. (2005) · Molecular Microbiology

Bacterial Genetics and BiotechnologyGenomics and Phylogenetic Studies

Cited by 131

The Role of Bacillithiol in Gram-Positive Firmicutes

Chandrangsu, P., Loi, V. V., Antelmann, H., & Helmann, J. D. (2018) · Antioxidants & Redox Signaling

Redox biology and oxidative stressBacterial Genetics and Biotechnology

Cited by 120

Sequential induction of Fur-regulated genes in response to iron limitation in Bacillus subtilis

Pi, H., & Helmann, J. D. (2017) · Proceedings of the National Academy of Sciences

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 109

Sequential binding and sensing of Zn(II) by Bacillus subtilis Zur

Ma, Z., Gabriel, S. E., & Helmann, J. D. (2011) · Nucleic Acids Research

Bacterial Genetics and BiotechnologyProtein Structure and Dynamics

Cited by 98

Bacillithiol is a major buffer of the labile zinc pool in Bacillus subtilis

Ma, Z., Chandrangsu, P., Helmann, T. C., Romsang, A., Gaballa, A., & Helmann, J. D. (2014) · Molecular Microbiology

Bacterial Genetics and BiotechnologyTrace Elements in Health

Cited by 96

Ferrous iron efflux systems in bacteria

Pi, H., & Helmann, J. D. (2017) · Metallomics

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 93

Bacillus subtilis MntR coordinates the transcriptional regulation of manganese uptake and efflux systems

Huang, X., Shin, J., Pinochet‐Barros, A., Su, T. T., & Helmann, J. D. (2017) · Molecular Microbiology

Bacterial Genetics and BiotechnologyHeavy Metal Exposure and Toxicity

Cited by 93

PfeT, a P1B4‐type ATP ase, effluxes ferrous iron and protects Bacillus subtilis against iron intoxication

Guan, G., Pinochet‐Barros, A., Gaballa, A., Patel, S. J., Argüello, J. M., & Helmann, J. D. (2015) · Molecular Microbiology

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 93

A Global Investigation of the Bacillus subtilis Iron-Sparing Response Identifies Major Changes in Metabolism

Smaldone, G. T., Revelles, O., Gaballa, A., Sauer, U., Antelmann, H., & Helmann, J. D. (2012) · Journal of Bacteriology

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 87

Redox Sensing by Fe 2+ in Bacterial Fur Family Metalloregulators

Pinochet-Barros, A., & Helmann, J. D. (2018) · Antioxidants & Redox Signaling

Bacterial Genetics and BiotechnologyRedox biology and oxidative stress

Cited by 85

Derepression of the Bacillus subtilis PerR Peroxide Stress Response Leads to Iron Deficiency

Faulkner, M. J., Ma, Z., Fuangthong, M., & Helmann, J. D. (2012) · Journal of Bacteriology

Bacterial Genetics and BiotechnologyRedox biology and oxidative stress

Cited by 76

Bacillus subtilis FolE is sustained by the ZagA zinc metallochaperone and the alarmone ZTP under conditions of zinc deficiency

Chandrangsu, P., Huang, X., Gaballa, A., & Helmann, J. D. (2019) · Molecular Microbiology

Bacterial Genetics and BiotechnologyBiochemical and Molecular Research

Cited by 72