Proud, Christopher G.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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The mTOR pathway in the control of protein synthesis

Wang, X., & Proud, C. G. (2006) · Physiology

PI3K/AKT/mTOR signaling in cancerMuscle metabolism and nutrition

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Signalling to translation: How signal transduction pathways control the protein synthetic machinery

Proud, C. G. (2007) · Biochemical Journal

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

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Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

Browne, G. J., Finn, S. G., & Proud, C. G. (2004) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

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Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

Balgi, A. D., Fonseca, B. D., Donohue, E., Tsang, T. C. F., Lajoie, P., Proud, C. G., Nabi, I. R., & Roberge, M. (2009) · PLoS ONE

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

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Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte

Chan, A. Y. M., Soltys, C.-L. M., Young, M. E., Proud, C. G., & Dyck, J. R. B. (2004) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

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Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

BEUGNET, A., TEE, A. R., TAYLOR, P. M., & PROUD, C. G. (2003) · Biochemical Journal

PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms

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Hepatic Selective Insulin Resistance at the Intersection of Insulin Signaling and Metabolic Dysfunction-Associated Steatotic Liver Disease

Bo, T., Gao, L., Yao, Z., Shao, S., Wang, X., Proud, C. G., & Zhao, J. (2024) · Cell Metabolism

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

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MTOR inhibitors in cancer therapy

Xie, J., Wang, X., & Proud, C. G. (2016) · F1000Research

PI3K/AKT/mTOR signaling in cancerAdvanced Breast Cancer Therapies

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mTORC1 signaling controls multiple steps in ribosome biogenesis

Iadevaia, V., Liu, R., & Proud, C. G. (2014) · Seminars in Cell & Developmental Biology

PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms

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Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1

Averous, J., Fonseca, B. D., & Proud, C. G. (2008) · Oncogene

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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Two-Stage Translational Control of Dentate Gyrus LTP Consolidation Is Mediated by Sustained BDNF-TrkB Signaling to MNK

Panja, D., Kenney, J. W., D’Andrea, L., Zalfa, F., Vedeler, A., Wibrand, K., Fukunaga, R., Bagni, C., Proud, C. G., & Bramham, C. R. (2014) · Cell Reports

Neuroscience and Neuropharmacology ResearchRNA and protein synthesis mechanisms

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Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner

Christie, G. R., Hajduch, E., Hundal, H. S., Proud, C. G., & Taylor, P. M. (2002) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms

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Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases

Liu, R., & Proud, C. G. (2016) · Acta Pharmacologica Sinica

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

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MNK Inhibition Sensitizes KRAS -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression

Knight, J. R. P., Alexandrou, C., Skalka, G. L., Vlahov, N., Pennel, K., Officer, L., Teodosio, A., Kanellos, G., Gay, D. M., May-Wilson, S., et al. (2021) · Cancer Discovery

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BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1

Genheden, M., Kenney, J. W., Johnston, H. E., Manousopoulou, A., Garbis, S. D., & Proud, C. G. (2015) · The Journal of Neuroscience

RNA and protein synthesis mechanismsGenetics and Neurodevelopmental Disorders

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Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats

Wilson, G. J., Layman, D. K., Moulton, C. J., Norton, L. E., Anthony, T. G., Proud, C. G., Rupassara, S. I., & Garlick, P. J. (2011) · American Journal of Physiology-Endocrinology and Metabolism

Muscle metabolism and nutritionMetabolism, Diabetes, and Cancer

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The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding

Beggs, J. E., Tian, S., Jones, G. G., Xie, J., Iadevaia, V., Jenei, V., Thomas, G., & Proud, C. G. (2015) · Biochemical Journal

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

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eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures

Heise, C., Taha, E., Murru, L., Ponzoni, L., Cattaneo, A., Guarnieri, F. C., Montani, C., Mossa, A., Vezzoli, E., Ippolito, G., et al. (2016) · Cerebral Cortex

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

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Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains

Pigott, C. R., Mikolajek, H., Moore, C. E., Finn, S. J., Phippen, C. W., Werner, J. M., & Proud, C. G. (2012) · Biochemical Journal

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