Lin, Xihong

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Taliun, D., Harris, D. N., Kessler, M. D., Carlson, J., Szpiech, Z. A., Torres, R., Taliun, S. A. G., Corvelo, A., Gogarten, S. M., Kang, H. M., et al. (2021) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 2,213

Association of public health interventions with the epidemiology of the COVID-19 outbreak in Wuhan, China

Pan, A., Liu, L., Wang, C., Guo, H., Hao, X., Wang, Q., Huang, J., He, N., Yu, H., Lin, X., et al. (2020) · JAMA

COVID-19 epidemiological studiesCOVID-19 Prevention and Impact

Cited by 1,931

LKB1 modulates lung cancer differentiation and metastasis

Ji, H., Ramsey, M. R., Hayes, D. N., Fan, C., McNamara, K., Kozlowski, P., Torrice, C., Wu, M. C., Shimamura, T., Perera, S. A., et al. (2007) · Nature

Lung Cancer Research StudiesLung Cancer Treatments and Mutations

Cited by 1,064

Rare-Variant Association Analysis: Study Designs and Statistical Tests

Lee, S., Abecasis, G. R., Boehnke, M., & Lin, X. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 1,042

Federated learning for predicting clinical outcomes in patients with COVID-19

Dayan, I., Roth, H. R., Zhong, A., Harouni, A., Gentili, A., Abidin, A. Z., Liu, A., Costa, A. B., Wood, B. J., Tsai, C.-S., et al. (2021) · Nature Medicine

Machine Learning in HealthcareCOVID-19 diagnosis using AI

Cited by 842

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Bick, A. G., Weinstock, J. S., Nandakumar, S. K., Fulco, C. P., Bao, E. L., Zekavat, S. M., Szeto, M. D., Liao, X., Leventhal, M. J., Nasser, J., et al. (2020) · Nature

Acute Myeloid Leukemia ResearchGenetic Associations and Epidemiology

Cited by 733

Sequence Kernel Association Tests for the Combined Effect of Rare and Common Variants

Ionita-Laza, I., Lee, S., Makarov, V., Buxbaum, J. D., & Lin, X. (2013) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 433

A Powerful and Flexible Multilocus Association Test for Quantitative Traits

Kwee, L. C., Liu, D., Lin, X., Ghosh, D., & Epstein, M. P. (2008) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 227

Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans

Cade, B. E., Chen, H., Stilp, A. M., Gleason, K. J., Sofer, T., Ancoli-Israel, S., Arens, R., Bell, G. I., Below, J. E., Bjonnes, A. C., et al. (2016) · American Journal of Respiratory and Critical Care Medicine

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 134

Accelerated biological aging elevates the risk of cardiometabolic multimorbidity and mortality

Jiang, M., Tian, S., Liu, S., Wang, Y., Guo, X., Huang, T., Lin, X., Belsky, D. W., Baccarelli, A. A., & Gao, X. (2024) · Nature Cardiovascular Research

Chronic Disease Management StrategiesFrailty in Older Adults

Cited by 117

Progression of Subclinical Coronary Atherosclerosis: Does Obesity Make a Difference?

Cassidy, A. E., Bielak, L. F., Zhou, Y., Sheedy, P. F., Turner, S. T., Breen, J. F., Araoz, P. A., Kullo, I. J., Lin, X., & Peyser, P. A. (2005) · Circulation

Cardiac Imaging and DiagnosticsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 114

A Comparison of Methods for Estimating the Causal Effect of a Treatment in Randomized Clinical Trials Subject to Noncompliance

Little, R. J., Long, Q., & Lin, X. (2009) · Biometrics

Advanced Causal Inference TechniquesStatistical Methods in Clinical Trials

Cited by 111

Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate Cancer

Wang, L., Rotnitzky, A., Lin, X., Millikan, R. E., & Thall, P. F. (2012) · Journal of the American Statistical Association

Statistical Methods in Clinical TrialsAdvanced Causal Inference Techniques

Cited by 108

Clinicopathologic and Genomic Factors Impacting Efficacy of First-Line Chemoimmunotherapy in Advanced NSCLC

Alessi, J. V., Elkrief, A., Ricciuti, B., Wang, X., Cortellini, A., Vaz, V. R., Lamberti, G., Frias, R. L., Venkatraman, D., Fulgenzi, C. A. M., et al. (2023) · Journal of Thoracic Oncology

Cancer Immunotherapy and BiomarkersLung Cancer Treatments and Mutations

Cited by 97

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease

Katz, D. H., Tahir, U. A., Bick, A. G., Pampana, A., Ngo, D., Benson, M. D., Yu, Z., Robbins, J. M., Chen, Z.-Z., Cruz, D. E., et al. (2022) · Circulation

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 92

Joint analysis of SNP and gene expression data in genetic association studies of complex diseases

Huang, Y.-T., VanderWeele, T. J., & Lin, X. (2014) · The Annals of Applied Statistics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 88

Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea–related Quantitative Trait Locus in Men

Chen, H., Cade, B. E., Gleason, K. J., Bjonnes, A. C., Stilp, A. M., Sofer, T., Conomos, M. P., Ancoli-Israel, S., Arens, R., Azarbarzin, A., et al. (2018) · American Journal of Respiratory Cell and Molecular Biology

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 82

Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans

Wang, H., Cade, B. E., Sofer, T., Sands, S. A., Chen, H., Browning, S. R., Stilp, A. M., Louie, T. L., Thornton, T. A., Johnson, W. C., et al. (2019) · Human Molecular Genetics

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 56

Comparison of Heritability Estimation and Linkage Analysis for Multiple Traits Using Principal Component Analyses

Liang, J., Cade, B. E., Wang, H., Chen, H., Gleason, K. J., Larkin, E. K., Saxena, R., Lin, X., Redline, S., & Zhu, X. (2016) · Genetic Epidemiology

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 41

Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

Cade, B. E., Chen, H., Stilp, A. M., Louie, T., Ancoli-Israel, S., Arens, R., Barfield, R., Below, J. E., Cai, J., Conomos, M. P., et al. (2019) · PLOS Genetics

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 39

A geometric perspective on the power of principal component association tests in multiple phenotype studies

Liu, Z., & Lin, X. (2019) · Journal of the American Statistical Association

Genetic Associations and EpidemiologyStatistical Methods and Applications

Cited by 36

Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level

Liang, J., Cade, B. E., He, K. Y., Wang, H., Lee, J., Sofer, T., Williams, S., Li, R., Chen, H., Gottlieb, D. J., et al. (2019) · The American Journal of Human Genetics

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 21

A comparison of principal component methods between multiple phenotype regression and multiple SNP regression in genetic association studies

Liu, Z., Barnett, I., & Lin, X. (2020) · The Annals of Applied Statistics

Genetic Associations and EpidemiologyStatistical Methods and Applications

Cited by 7