Uitterlinden, André G.

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.

Porcu, E., Rüeger, S., Lepik, K., eQTLGen Consortium, Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., et al. (2019) · Nature Communications

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 322

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

Perry, J. R. B., Stolk, L., Franceschini, N., Lunetta, K. L., Zhai, G., McArdle, P. F., Smith, A. V., Aspelund, T., Bandinelli, S., Boerwinkle, E., et al. (2009) · Nature Genetics

Hypothalamic control of reproductive hormonesGenetic Associations and Epidemiology

Cited by 294

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., et al. (2014) · Proceedings of the National Academy of Sciences

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 258

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

Yu, Y., Bhangale, T. R., Fagerness, J., Ripke, S., Thorleifsson, G., Tan, P. L., Souied, E. H., Richardson, A. J., Merriam, J. E., Buitendijk, G. H. S., et al. (2011) · Human Molecular Genetics

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 254

A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation

Coviello, A. D., Haring, R., Wellons, M., Vaidya, D., Lehtimäki, T., Keildson, S., Lunetta, K. L., He, C., Fornage, M., Lagou, V., et al. (2012) · PLoS Genetics

Genetic Associations and EpidemiologyHormonal and reproductive studies

Cited by 250

The Rotterdam Study: 2010 objectives and design update

Hofman, A., Breteler, M. M. B., van Duijn, C. M., Janssen, H. L. A., Krestin, G. P., Kuipers, E. J., Stricker, B. H. C., Tiemeier, H., Uitterlinden, A. G., Vingerling, J. R., et al. (2009) · European Journal of Epidemiology

Cardiovascular Health and Risk FactorsHealth, Environment, Cognitive Aging

Cited by 244

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, G., Liu, C., O’Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., et al. (2016) · Proceedings of the National Academy of Sciences

Fibroblast Growth Factor ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 241

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

Tanaka, T., Ngwa, J. S., van Rooij, F. J., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J., et al. (2013) · The American Journal of Clinical Nutrition

Nutrition, Genetics, and DiseaseGenetic Associations and Epidemiology

Cited by 226

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease

Holstege, H., Hulsman, M., Charbonnier, C., Grenier-Boley, B., Quenez, O., Grozeva, D., van Rooij, J. G. J., Sims, R., Ahmad, S., Amin, N., et al. (2022) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 226

Genetic determinants of serum testosterone concentrations in men

Ohlsson, C., Wallaschofski, H., Lunetta, K. L., Stolk, L., Perry, J. R. B., Koster, A., Petersen, A.-K., Eriksson, J., Lehtimäki, T., Huhtaniemi, I. T., et al. (2011) · PLoS Genetics

Hormonal and reproductive studiesGenetic Associations and Epidemiology

Cited by 224

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., et al. (2014) · PLoS Genetics

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 218

Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci

Liu, F., Wollstein, A., Hysi, P. G., Ankra-Badu, G. A., Spector, T. D., Park, D., Zhu, G., Larsson, M., Duffy, D. L., Montgomery, G. W., et al. (2010) · PLoS Genetics

Genetic Associations and Epidemiologymelanin and skin pigmentation

Cited by 191

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

GROUP investigators, Børglum, A. D., Demontis, D., Grove, J., Pallesen, J., Hollegaard, M. V., Pedersen, C. B., Hedemand, A., Mattheisen, M., Uitterlinden, A., et al. (2014) · Molecular Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 186

A Genome-Wide Association Study of Depressive Symptoms

Hek, K., Demirkan, A., Lahti, J., Terracciano, A., Teumer, A., Cornelis, M. C., Amin, N., Bakshis, E., Baumert, J., Ding, J., et al. (2013) · Biological Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 172

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up

Liu, F., Visser, M., Duffy, D. L., Hysi, P. G., Jacobs, L. C., Lao, O., Zhong, K., Walsh, S., Chaitanya, L., Wollstein, A., et al. (2015) · Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

Cited by 172

FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

Qi, Q., Kilpeläinen, T. O., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., et al. (2014) · Human Molecular Genetics

Nutrition, Genetics, and DiseaseGenetic Associations and Epidemiology

Cited by 167

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., et al. (2016) · Molecular Psychiatry

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 147

High prevalence of vertebral fractures despite normal bone mineral density in patients with long-term controlled acromegaly

Wassenaar, M. J. E., Biermasz, N. R., Hamdy, N. A. T., Zillikens, M. C., van Meurs, J. B. J., Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Stokkel, M. P. M., Roelfsema, F., et al. (2011) · European Journal of Endocrinology

Pituitary Gland Disorders and TreatmentsBone health and osteoporosis research

Cited by 144

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., et al. (2019) · Nature Communications

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 143

Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: New evidence for a gene–environment interaction

Bet, P. M., Penninx, B. W. J. H., Bochdanovits, Z., Uitterlinden, A. G., Beekman, A. T. F., van Schoor, N. M., Deeg, D. J. H., & Hoogendijk, W. J. G. (2009) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Stress Responses and CortisolGenetic Associations and Epidemiology

Cited by 138

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M.-H., Leening, M. J. G., Völker, U., Großmann, V., Brody, J. A., Irvin, M. R., et al. (2017) · Journal of Clinical Investigation

Genetic Associations and EpidemiologyCardiac electrophysiology and arrhythmias

Cited by 129

Thyroid function characteristics and determinants: the Rotterdam study.

Chaker, L., Korevaar, T. I. M., Medici, M., Uitterlinden, A. G., Hofman, A., Dehghan, A., Franco, O. H., & Peeters, R. P. (2016) · Thyroid

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 118