Uitterlinden, André G.

Coronary Artery Calcium Score and Polygenic Risk Score for the Prediction of Coronary Heart Disease Events

Khan, S. S., Post, W. S., Guo, X., Tan, J., Zhu, F., Bos, D., Sedaghati-Khayat, B., van Rooij, J., Aday, A., Allen, N. B., et al. (2023) · JAMA

Cardiac Imaging and DiagnosticsGenetic Associations and Epidemiology

Cited by 117

Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans

Jacobs, L. C., Wollstein, A., Lao, O., Hofman, A., Klaver, C. C., Uitterlinden, A. G., Nijsten, T., Kayser, M., & Liu, F. (2013) · Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

Cited by 99

Novel genetic loci affecting facial shape variation in humans

Xiong, Z., Dankova, G., Howe, L. J., Lee, M. K., Hysi, P. G., de Jong, M. A., Zhu, G., Adhikari, K., Li, D., Li, Y., et al. (2019) · eLife

Genetic Associations and EpidemiologyMorphological variations and asymmetry

Cited by 92

Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial

van Wijngaarden, J. P., Swart, K. M., Enneman, A. W., Dhonukshe-Rutten, R. A., van Dijk, S. C., Ham, A. C., Brouwer-Brolsma, E. M., van der Zwaluw, N. L., Sohl, E., van Meurs, J. B., et al. (2014) · The American Journal of Clinical Nutrition

Folate and B Vitamins ResearchBone health and osteoporosis research

Cited by 91

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3: GWAS of Height-Adjusted BMI

Stergiakouli, E., Gaillard, R., Tavaré, J. M., Balthasar, N., Loos, R. J., Taal, H. R., Evans, D. M., Rivadeneira, F., St Pourcain, B., Uitterlinden, A. G., et al. (2014) · Obesity

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 90

Meta-Analysis Investigating Associations Between Healthy Diet and Fasting Glucose and Insulin Levels and Modification by Loci Associated With Glucose Homeostasis in Data From 15 Cohorts

Nettleton, J. A., Hivert, M.-F., Lemaitre, R. N., McKeown, N. M., Mozaffarian, D., Tanaka, T., Wojczynski, M. K., Hruby, A., Djoussé, L., Ngwa, J. S., et al. (2013) · American Journal of Epidemiology

Nutrition, Genetics, and DiseaseNutritional Studies and Diet

Cited by 89

Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts

Segna, D., Bauer, D. C., Feller, M., Schneider, C., Fink, H. A., Aubert, C. E., Collet, T. ‐., da Costa, B. R., Fischer, K., Peeters, R. P., et al. (2018) · Journal of Internal Medicine

Thyroid Disorders and TreatmentsBone health and osteoporosis research

Cited by 87

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects

Peyrot, W. J., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., de Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., et al. (2015) · Molecular Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 84

PAPSS2 deficiency causes androgen excess via impaired DHEA sulfation–in vitro and in vivo studies in a family harboring two novel PAPSS2 mutations

Oostdijk, W., Idkowiak, J., Mueller, J. W., House, P. J., Taylor, A. E., O'Reilly, M. W., Hughes, B. A., de Vries, M. C., Kant, S. G., Santen, G. W. E., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 81

Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder

Mühleisen, T. W., Mattheisen, M., Strohmaier, J., Degenhardt, F., Priebe, L., Schultz, C. C., Breuer, R., Meier, S., Hoffmann, P., Rivandeneira, F., et al. (2012) · Schizophrenia Research

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 80

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

Genetic association study of childhood aggression across raters, instruments, and age

Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., St Pourcain, B., Bolhuis, K., Palviainen, T., Zafarmand, H., et al. (2021) · Translational Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 71

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

The QT Interval International GWAS Consortium (QT-IGC), Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S.-P., Brunak, S., et al. (2014) · Nature Methods

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 71

A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies

Brautbar, A., Pompeii, L. A., Dehghan, A., Ngwa, J. S., Nambi, V., Virani, S. S., Rivadeneira, F., Uitterlinden, A. G., Hofman, A., Witteman, J. C. M., et al. (2012) · Atherosclerosis

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 71

A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels

Medici, M., van der Deure, W. M., Verbiest, M., Vermeulen, S. H., Hansen, P. S., Kiemeney, L. A., Hermus, A. R. M. M., Breteler, M. M., Hofman, A., Hegedüs, L., et al. (2011) · European Journal of Endocrinology

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 68

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., et al. (2019) · Molecular Psychiatry

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 66

Genome-wide association study of vascular dementia

Schrijvers, E. M. C., Schürmann, B., Koudstaal, P. J., van den Bussche, H., Van Duijn, C. M., Hentschel, F., Heun, R., Hofman, A., Jessen, F., Kölsch, H., et al. (2012) · Stroke

Dementia and Cognitive Impairment ResearchGenetic Associations and Epidemiology

Cited by 61

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

Polfus, L. M., Khajuria, R. K., Schick, U. M., Pankratz, N., Pazoki, R., Brody, J. A., Chen, M.-H., Auer, P. L., Floyd, J. S., Huang, J., et al. (2016) · The American Journal of Human Genetics

Platelet Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 54

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2

van den Akker, E. B., Pitts, S. J., Deelen, J., Moed, M. H., Potluri, S., van Rooij, J., Suchiman, H. E. D., Lakenberg, N., de Dijcker, W. J., Uitterlinden, A. G., et al. (2016) · Blood

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 49

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J.-W., et al. (2022) · Nature Communications

Cardiac electrophysiology and arrhythmiasGenetic Associations and Epidemiology

Cited by 49

Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans

Olfson, E., Saccone, N. L., Johnson, E. O., Chen, L.-S., Culverhouse, R., Doheny, K., Foltz, S. M., Fox, L., Gogarten, S. M., Hartz, S., et al. (2016) · Molecular Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 43

A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

Sung, Y. J., de las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., et al. (2019) · Human Molecular Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 43

A rare missense variant in RCL1 segregates with depression in extended families.

Amin, N., de Vrij, F. M. S., Baghdadi, M., Brouwer, R. W. W., van Rooij, J. G. J., Jovanova, O., Uitterlinden, A. G., Hofman, A., Janssen, H. L. A., Darwish Murad, S., et al. (2018) · Molecular Psychiatry

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 37

Continuity of Genetic Risk for Aggressive Behavior Across the Life-Course

van der Laan, C. M., Morosoli-García, J. J., van de Weijer, S. G. A., Colodro-Conde, L., the ACTION Consortium, Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., et al. (2021) · Behavior Genetics

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 24