Hayashizaki, Yoshihide

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature

Genomics and Phylogenetic StudiesGenetic Associations and Epidemiology

Cited by 24,216

Landscape of transcription in human cells

Djebali, S., Davis, C. A., Merkel, A., Dobin, A., Lassmann, T., Mortazavi, A., Tanzer, A., Lagarde, J., Lin, W., Schlesinger, F., et al. (2012) · Nature

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 5,187

An atlas of active enhancers across human cell types and tissues

The FANTOM Consortium, Andersson, R., Gebhard, C., Miguel-Escalada, I., Hoof, I., Bornholdt, J., Boyd, M., Chen, Y., Zhao, X., Schmidl, C., et al. (2014) · Nature

Genomics and Chromatin DynamicsCancer-related molecular mechanisms research

Cited by 2,550

Genome-wide analysis of mammalian promoter architecture and evolution

Carninci, P., Sandelin, A., Lenhard, B., Katayama, S., Shimokawa, K., Ponjavic, J., Semple, C. A. M., Taylor, M. S., Engström, P. G., Frith, M. C., et al. (2006) · Nature Genetics

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 1,350

An atlas of human long non-coding RNAs with accurate 5′ ends

Hon, C.-C., Ramilowski, J. A., Harshbarger, J., Bertin, N., Rackham, O. J. L., Gough, J., Denisenko, E., Schmeier, S., Poulsen, T. M., Severin, J., et al. (2017) · Nature

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 1,007

Gateways to the FANTOM5 promoter level mammalian expression atlas

Lizio, M., Harshbarger, J., Shimoji, H., Severin, J., Kasukawa, T., Sahin, S., Abugessaisa, I., Fukuda, S., Hori, F., Ishikawa-Kato, S., et al. (2015) · Genome Biology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 871

An atlas of combinatorial transcriptional regulation in mouse and man

Ravasi, T., Suzuki, H., Cannistraci, C. V., Katayama, S., Bajic, V. B., Tan, K., Akalin, A., Schmeier, S., Kanamori-Katayama, M., Bertin, N., et al. (2010) · Cell

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 715

An integrated expression atlas of miRNAs and their promoters in human and mouse

The FANTOM Consortium, de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., et al. (2017) · Nature Biotechnology

MicroRNA in disease regulationGenomics and Chromatin Dynamics

Cited by 561

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

Maida, Y., Yasukawa, M., Furuuchi, M., Lassmann, T., Possemato, R., Okamoto, N., Kasim, V., Hayashizaki, Y., Hahn, W. C., & Masutomi, K. (2009) · Nature

Telomeres, Telomerase, and SenescenceRNA Interference and Gene Delivery

Cited by 384

The reeler gene encodes a protein with an EGF–like motif expressed by pioneer neurons

Hirotsune, S., Takahara, T., Sasaki, N., Hirose, K., Yoshiki, A., Ohashi, T., Kusakabe, M., Murakami, Y., Muramatsu, M., Watanabe, S., et al. (1995) · Nature Genetics

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 345

FANTOM5 CAGE profiles of human and mouse samples

Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., et al. (2017) · Scientific Data

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 310

Genomic Instability of iPSCs: Challenges Towards Their Clinical Applications

Yoshihara, M., Hayashizaki, Y., & Murakawa, Y. (2017) · Stem Cell Reviews and Reports

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 283

Thyroid-stimulating hormone (TSH) deficiency caused by a single base substitution in the CAGYC region of the beta-subunit

Hayashizaki, Y., Hiraoka, Y., Endo, Y., Miyai, K., & Matsubara, K. (1989) · The EMBO Journal

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 152

Comparison of CAGE and RNA-seq transcriptome profiling using clonally amplified and single-molecule next-generation sequencing

Kawaji, H., Lizio, M., Itoh, M., Kanamori-Katayama, M., Kaiho, A., Nishiyori-Sueki, H., Shin, J. W., Kojima-Ishiyama, M., Kawano, M., Murata, M., et al. (2014) · Genome Research

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 109

RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells

Suzuki, T., Shimizu, Y., Furuhata, E., Maeda, S., Kishima, M., Nishimura, H., Enomoto, S., Hayashizaki, Y., & Suzuki, H. (2017) · Blood Advances

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 87

Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts

Suzuki, T., Nakano-Ikegaya, M., Yabukami-Okuda, H., de Hoon, M., Severin, J., Saga-Hatano, S., Shin, J. W., Kubosaki, A., Simon, C., Hasegawa, Y., et al. (2012) · PLoS ONE

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 41

A transient disruption of fibroblastic transcriptional regulatory network facilitates trans-differentiation

Tomaru, Y., Hasegawa, R., Suzuki, T., Sato, T., Kubosaki, A., Suzuki, M., Kawaji, H., Forrest, A. R. R., Hayashizaki, Y., FANTOM Consortium, et al. (2014) · Nucleic Acids Research

Pluripotent Stem Cells ResearchGene Regulatory Network Analysis

Cited by 39

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells

Kubosaki, A., Lindgren, G., Tagami, M., Simon, C., Tomaru, Y., Miura, H., Suzuki, T., Arner, E., Forrest, A. R. R., Irvine, K. M., et al. (2010) · Molecular Immunology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 29

Regulatory interdependence of myeloid transcription factors revealed by Matrix RNAi analysis

Tomaru, Y., Simon, C., Forrest, A. R., Miura, H., Kubosaki, A., Hayashizaki, Y., & Suzuki, M. (2009) · Genome biology

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 21

Establishment of single-cell screening system for the rapid identification of transcriptional modulators involved in direct cell reprogramming

Shin, J. W., Suzuki, T., Ninomiya, N., Kishima, M., Hasegawa, Y., Kubosaki, A., Yabukami, H., Hayashizaki, Y., & Suzuki, H. (2012) · Nucleic Acids Research

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 12