Ma’ayan, Avi

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

Chen, E. Y., Tan, C. M., Kou, Y., Duan, Q., Wang, Z., Meirelles, G. V., Clark, N. R., & Ma’ayan, A. (2013) · BMC Bioinformatics

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 7,814

Synaptic, transcriptional and chromatin genes disrupted in autism

Study, T. D., De Rubeis, S., Autism, H. M. C. F., UK10K Consortium, The Autism Sequencing Consortium, He, X., Goldberg, A. P., Poultney, C. S., Samocha, K., Ercument Cicek, A., et al. (2014) · Nature

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 2,746

Patterns and rates of exonic de novo mutations in autism spectrum disorders

Neale, B. M., Kou, Y., Liu, L., Ma’ayan, A., Samocha, K. E., Sabo, A., Lin, C.-F., Stevens, C., Wang, L.-S., Makarov, V., et al. (2012) · Nature

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,734

The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins

Rouillard, A. D., Gundersen, G. W., Fernandez, N. F., Wang, Z., Monteiro, C. D., McDermott, M. G., & Ma’ayan, A. (2016) · Database

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 1,515

ChEA3: transcription factor enrichment analysis by orthogonal omics integration

Keenan, A. B., Torre, D., Lachmann, A., Leong, A. K., Wojciechowicz, M. L., Utti, V., Jagodnik, K. M., Kropiwnicki, E., Wang, Z., & Ma’ayan, A. (2019) · Nucleic Acids Research

Bioinformatics and Genomic NetworksGenomics and Chromatin Dynamics

Cited by 1,136

Single-cell immune landscape of human atherosclerotic plaques

Fernandez, D. M., Rahman, A. H., Fernandez, N. F., Chudnovskiy, A., Amir, E.-A. D., Amadori, L., Khan, N. S., Wong, C. K., Shamailova, R., Hill, C. A., et al. (2019) · Nature Medicine

Atherosclerosis and Cardiovascular DiseasesCerebrovascular and Carotid Artery Diseases

Cited by 970

Massive mining of publicly available RNA-seq data from human and mouse

Lachmann, A., Torre, D., Keenan, A. B., Jagodnik, K. M., Lee, H. J., Wang, L., Silverstein, M. C., & Ma’ayan, A. (2018) · Nature Communications

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 701

Induction of a hemogenic program in mouse fibroblasts

Pereira, C.-F., Chang, B., Qiu, J., Niu, X., Papatsenko, D., Hendry, C. E., Clark, N. R., Nomura-Kitabayashi, A., Kovacic, J. C., Ma’ayan, A., et al. (2013) · Cell stem cell

Hematopoietic Stem Cell TransplantationPluripotent Stem Cells Research

Cited by 216

An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin

Sennett, R., Wang, Z., Rezza, A., Grisanti, L., Roitershtein, N., Sicchio, C., Mok, K. W., Heitman, N. J., Clavel, C., Ma’ayan, A., et al. (2015) · Developmental Cell

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 211

Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles

Rezza, A., Wang, Z., Sennett, R., Qiao, W., Wang, D., Heitman, N., Mok, K. W., Clavel, C., Yi, R., Zandstra, P., et al. (2016) · Cell Reports

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 197

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Sangodkar, J., Perl, A., Tohme, R., Kiselar, J., Kastrinsky, D. B., Zaware, N., Izadmehr, S., Mazhar, S., Wiredja, D. D., O’Connor, C. M., et al. (2017) · Journal of Clinical Investigation

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 196

L1000FWD: fireworks visualization of drug-induced transcriptomic signatures

Wang, Z., Lachmann, A., Keenan, A. B., & Ma’ayan, A. (2018) · Bioinformatics

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 195

Data Portal for the Library of Integrated Network-based cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

Koleti, A., Terryn, R., Stathias, V., Chung, C., Cooper, D. J., Turner, J. P., Vidović, D., Forlin, M., Kelley, T. T., D’Urso, A., et al. (2018) · Nucleic Acids Research

Bioinformatics and Genomic NetworksResearch Data Management Practices

Cited by 193

Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder

Poultney, C. S., Goldberg, A. P., Drapeau, E., Kou, Y., Harony-Nicolas, H., Kajiwara, Y., De Rubeis, S., Durand, S., Stevens, C., Rehnström, K., et al. (2013) · The American Journal of Human Genetics

Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases

Cited by 169

LINCS Data Portal 2.0: next generation access point for perturbation-response signatures

Stathias, V., Turner, J., Koleti, A., Vidovic, D., Cooper, D., Fazel-Najafabadi, M., Pilarczyk, M., Terryn, R., Chung, C., Umeano, A., et al. (2020) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 161

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

Niepel, M., Hafner, M., Mills, C. E., Subramanian, K., Williams, E. H., Chung, M., Gaudio, B., Barrette, A. M., Stern, A. D., Hu, B., et al. (2019) · Cell Systems

Scientific Computing and Data ManagementAnimal testing and alternatives

Cited by 133

Habenular TCF7L2 links nicotine addiction to diabetes

Duncan, A., Heyer, M. P., Ishikawa, M., Caligiuri, S. P. B., Liu, X.-A., Chen, Z., Micioni Di Bonaventura, M. V., Elayouby, K. S., Ables, J. L., Howe, W. M., et al. (2019) · Nature

Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation

Cited by 119

Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells

Nakahara, F., Borger, D. K., Wei, Q., Pinho, S., Maryanovich, M., Zahalka, A. H., Suzuki, M., Cruz, C. D., Wang, Z., Xu, C., et al. (2019) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 99

Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects

Edwards, J. J., Rouillard, A. D., Fernandez, N. F., Wang, Z., Lachmann, A., Shankaran, S. S., Bisgrove, B. W., Demarest, B., Turan, N., Srivastava, D., et al. (2020) · JACC: Basic to Translational Science

Congenital heart defects researchCardiomyopathy and Myosin Studies

Cited by 27