Storbeck, Karl-Heinz

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review

Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology

Metabolomics and Mass Spectrometry StudiesAdrenal Hormones and Disorders

Cited by 450

11-Oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome

O’Reilly, M. W., Kempegowda, P., Jenkinson, C., Taylor, A. E., Quanson, J. L., Storbeck, K.-H., & Arlt, W. (2017) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersAdrenal Hormones and Disorders

Cited by 267

Intracrine androgen biosynthesis, metabolism and action revisited

Schiffer, L., Arlt, W., & Storbeck, K.-H. (2018) · Molecular and Cellular Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 217

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?

Storbeck, K.-H., Bloem, L. M., Africander, D., Schloms, L., Swart, P., & Swart, A. C. (2013) · Molecular and Cellular Endocrinology

Prostate Cancer Treatment and ResearchHormonal and reproductive studies

Cited by 198

11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which can No Longer be Ignored

Pretorius, E., Africander, D. J., Vlok, M., Perkins, M. S., Quanson, J., & Storbeck, K.-H. (2016) · PLOS ONE

Prostate Cancer Treatment and ResearchHormonal and reproductive studies

Cited by 148

A new dawn for androgens: novel lessons from 11-oxygenated C19 steroids

Pretorius, E., Arlt, W., & Storbeck, K.-H. (2017) · Molecular and Cellular Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 142

Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism

Storbeck, K.-H., Schiffer, L., Baranowski, E. S., Chortis, V., Prete, A., Barnard, L., Gilligan, L. C., Taylor, A. E., Idkowiak, J., Arlt, W., et al. (2019) · Endocrine Reviews

Adrenal Hormones and DisordersMetabolism and Genetic Disorders

Cited by 141

11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione

Swart, A. C., Schloms, L., Storbeck, K.-H., Bloem, L. M., Toit, T. D., Quanson, J. L., Rainey, W. E., & Swart, P. (2013) · The Journal of Steroid Biochemistry and Molecular Biology

Hormonal Regulation and HypertensionProstate Cancer Treatment and Research

Cited by 125

Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia

Jones, C. M., Mallappa, A., Reisch, N., Nikolaou, N., Krone, N., Hughes, B. A., O’Neil, D. M., Whitaker, M. J., Tomlinson, J. W., Storbeck, K.-H., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 74

11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): implications for castration resistant prostate cancer

Barnard, M., Quanson, J. L., Mostaghel, E., Pretorius, E., Snoep, J. L., & Storbeck, K.-H. (2018) · The Journal of Steroid Biochemistry and Molecular Biology

Prostate Cancer Treatment and ResearchAldose Reductase and Taurine

Cited by 72

11β-Hydroxyandrostenedione: downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways

Swart, A. C., & Storbeck, K.-H. (2015) · Molecular and Cellular Endocrinology

Prostate Cancer Treatment and ResearchHormonal and reproductive studies

Cited by 68

The clinical and biochemical significance of 11-oxygenated androgens in human health and disease

Storbeck, K.-H., & O’Reilly, M. W. (2023) · European Journal of Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 63

Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride

Schiffer, L., Shaheen, F., Gilligan, L. C., Storbeck, K.-H., Hawley, J. M., Keevil, B. G., Arlt, W., & Taylor, A. E. (2022) · Journal of Chromatography B

Analytical Methods in PharmaceuticalsAnalytical Chemistry and Chromatography

Cited by 52

Advances in the analytical methodologies: profiling steroids in familiar pathways-challenging dogmas

Bloem, L. M., Storbeck, K.-H., Swart, P., du Toit, T., Schloms, L., & Swart, A. C. (2015) · The Journal of Steroid Biochemistry and Molecular Biology

Adrenal Hormones and DisordersMetabolomics and Mass Spectrometry Studies

Cited by 52

The utility of ultra-high performance supercritical fluid chromatography–tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis

Storbeck, K.-H., Gilligan, L., Jenkinson, C., Baranowski, E. S., Quanson, J. L., Arlt, W., & Taylor, A. E. (2018) · Journal of Chromatography B

Analytical Chemistry and ChromatographyMetabolomics and Mass Spectrometry Studies

Cited by 49

11-Oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool

Barnard, L., Schiffer, L., Louw du-Toit, R., Tamblyn, J. A., Chen, S., Africander, D., Arlt, W., Foster, P. A., & Storbeck, K.-H. (2021) · Endocrinology

Estrogen and related hormone effectsSteroid Chemistry and Biochemistry

Cited by 27

The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1

Barnard, L., Nikolaou, N., Louw, C., Schiffer, L., Gibson, H., Gilligan, L. C., Gangitano, E., Snoep, J., Arlt, W., Tomlinson, J. W., et al. (2020) · The Journal of Steroid Biochemistry and Molecular Biology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 25