Mattos, Carla

A Comprehensive Survey of Ras Mutations in Cancer

Prior, I. A., Lewis, P. D., & Mattos, C. (2012) · Cancer Research

Cancer Genomics and DiagnosticsProtein Kinase Regulation and GTPase Signaling

Cited by 2,063

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

Johnson, C. W., Reid, D., Parker, J. A., Salter, S., Knihtila, R., Kuzmic, P., & Mattos, C. (2017) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 133

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

Johnson, C. W., Lin, Y.-J., Reid, D., Parker, J., Pavlopoulos, S., Dischinger, P., Graveel, C., Aguirre, A. J., Steensma, M., Haigis, K. M., et al. (2019) · Cell Reports

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 89

An engineered protein antagonist of K-Ras/B-Raf interaction

Kauke, M. J., Traxlmayr, M. W., Parker, J. A., Kiefer, J. D., Knihtila, R., McGee, J., Verdine, G., Mattos, C., & Wittrup, K. D. (2017) · Scientific Reports

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 64

“Pathway drug cocktail”: targeting Ras signaling based on structural pathways

Nussinov, R., Tsai, C.-J., & Mattos, C. (2013) · Trends in Molecular Medicine

Protein Kinase Regulation and GTPase SignalingBioinformatics and Genomic Networks

Cited by 62