Washburn, Michael P.

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Hrecka, K., Hao, C., Gierszewska, M., Swanson, S. K., Kesik-Brodacka, M., Srivastava, S., Florens, L., Washburn, M. P., & Skowronski, J. (2011) · Nature

HIV Research and TreatmentVirus-based gene therapy research

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Evolutionarily Conserved Multisubunit RBL2/p130 and E2F4 Protein Complex Represses Human Cell Cycle-Dependent Genes in Quiescence

Litovchick, L., Sadasivam, S., Florens, L., Zhu, X., Swanson, S. K., Velmurugan, S., Chen, R., Washburn, M. P., Liu, X. S., & DeCaprio, J. A. (2007) · Molecular Cell

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

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DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly

Litovchick, L., Florens, L. A., Swanson, S. K., Washburn, M. P., & DeCaprio, J. A. (2011) · Genes & Development

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

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PTEN Counteracts FBXL2 to Promote IP3R3- and Ca2+-Mediated Apoptosis Limiting Tumour Growth

Kuchay, S., Giorgi, C., Simoneschi, D., Pagan, J., Missiroli, S., Saraf, A., Florens, L., Washburn, M. P., Collazo-Lorduy, A., Castillo-Martin, M., et al. (2017) · Nature

Cell death mechanisms and regulationIon Channels and Receptors

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Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

Sardiu, M. E., Cai, Y., Jin, J., Swanson, S. K., Conaway, R. C., Conaway, J. W., Florens, L., & Washburn, M. P. (2008) · Proceedings of the National Academy of Sciences

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 226

Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection

Srivastava, S., Swanson, S. K., Manel, N., Florens, L., Washburn, M. P., & Skowronski, J. (2008) · PLoS Pathogens

HIV Research and TreatmentUbiquitin and proteasome pathways

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Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling

Herz, H.-M., Morgan, M., Gao, X., Jackson, J., Rickels, R., Swanson, S. K., Florens, L., Washburn, M. P., Eissenberg, J. C., & Shilatifard, A. (2014) · Science

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

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Characterization of Cullin-box Sequences That Direct Recruitment of Cul2-Rbx1 and Cul5-Rbx2 Modules to Elongin BC-based Ubiquitin Ligases

Mahrour, N., Redwine, W. B., Florens, L., Swanson, S. K., Martin-Brown, S., Bradford, W. D., Staehling-Hampton, K., Washburn, M. P., Conaway, R. C., & Conaway, J. W. (2008) · Journal of Biological Chemistry

Ubiquitin and proteasome pathwaysGenomics and Chromatin Dynamics

Cited by 196

Delayed Correlation of mRNA and Protein Expression in Rapamycin-treated Cells and a Role for Ggc1 in Cellular Sensitivity to Rapamycin

Fournier, M. L., Paulson, A., Pavelka, N., Mosley, A. L., Gaudenz, K., Bradford, W. D., Glynn, E., Li, H., Sardiu, M. E., Fleharty, B., et al. (2010) · Molecular & Cellular Proteomics

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

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HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins

Hrecka, K., Hao, C., Shun, M.-C., Kaur, S., Swanson, S. K., Florens, L., Washburn, M. P., & Skowronski, J. (2016) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentDNA Repair Mechanisms

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Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2

Choi, J., Lee, K., Ingvarsdottir, K., Bonasio, R., Saraf, A., Florens, L., Washburn, M. P., Tadros, S., Green, M. R., & Busino, L. (2018) · Nature Cell Biology

Ubiquitin and proteasome pathwaysLymphoma Diagnosis and Treatment

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Swi/Snf dynamics on stress-responsive genes is governed by competitive bromodomain interactions

Dutta, A., Gogol, M., Kim, J.-H., Smolle, M., Venkatesh, S., Gilmore, J., Florens, L., Washburn, M. P., & Workman, J. L. (2014) · Genes & Development

Chromatin Remodeling and CancerGenomics and Chromatin Dynamics

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An integrated structural model of the DNA damage-responsive H3K4me3 binding WDR76:SPIN1 complex with the nucleosome

Liu, X., Zhang, Y., Wen, Z., Hao, Y., Banks, C. A. S., Cesare, J., Bhattacharya, S., Arvindekar, S., Lange, J. J., Xie, Y., et al. (2024) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsDNA Repair Mechanisms

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