Wolters, Paul J.

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

Aran, D., Looney, A. P., Liu, L., Wu, E., Fong, V., Hsu, A., Chak, S., Naikawadi, R. P., Wolters, P. J., Abate, A. R., et al. (2019) · Nature Immunology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSingle-cell and spatial transcriptomics

Cited by 4,984

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

Kim, K. K., Kugler, M. C., Wolters, P. J., Robillard, L., Galvez, M. G., Brumwell, A. N., Sheppard, D., & Chapman, H. A. (2006) · Proceedings of the National Academy of Sciences

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTGF-β signaling in diseases

Cited by 1,257

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

Fingerlin, T. E., Murphy, E., Zhang, W., Peljto, A. L., Brown, K. K., Steele, M. P., Loyd, J. E., Cosgrove, G. P., Lynch, D., Groshong, S., et al. (2013) · Nature Genetics

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisGenetic Associations and Epidemiology

Cited by 809

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

Liu, J., Divoux, A., Sun, J., Zhang, J., Clément, K., Glickman, J. N., Sukhova, G. K., Wolters, P. J., Du, J., Gorgun, C. Z., et al. (2009) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesMast cells and histamine

Cited by 796

Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis

Tsukui, T., Sun, K.-H., Wetter, J. B., Wilson-Kanamori, J. R., Hazelwood, L. A., Henderson, N. C., Adams, T. S., Schupp, J. C., Poli, S. D., Rosas, I. O., et al. (2020) · Nature Communications

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSingle-cell and spatial transcriptomics

Cited by 765

Predicting Survival Across Chronic Interstitial Lung Disease

Ryerson, C. J., Vittinghoff, E., Ley, B., Lee, J. S., Mooney, J. J., Jones, K. D., Elicker, B. M., Wolters, P. J., Koth, L. L., King, T. E., et al. (2014) · Chest

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and Treatments

Cited by 558

Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation

Stuart, B. D., Lee, J. S., Kozlitina, J., Noth, I., Devine, M. S., Glazer, C. S., Torres, F., Kaza, V., Girod, C. E., Jones, K. D., et al. (2014) · The Lancet Respiratory Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 310

Viral Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Wootton, S. C., Kim, D. S., Kondoh, Y., Chen, E., Lee, J. S., Song, J. W., Huh, J. W., Taniguchi, H., Chiu, C., Boushey, H., et al. (2011) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 285

Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis

Naikawadi, R. P., Disayabutr, S., Mallavia, B., Donne, M. L., Green, G., La, J. L., Rock, J. R., Looney, M. R., & Wolters, P. J. (2016) · JCI Insight

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 267

Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients

Araya, J., Cambier, S., Markovics, J. A., Wolters, P., Jablons, D., Hill, A., Finkbeiner, W., Jones, K., Broaddus, V. C., Sheppard, D., et al. (2007) · Journal of Clinical Investigation

Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseases

Cited by 257

Frailty phenotypes, disability, and outcomes in adult candidates for lung transplantation

Singer, J. P., Diamond, J. M., Gries, C. J., McDonnough, J., Blanc, P. D., Shah, R., Dean, M. Y., Hersh, B., Wolters, P. J., Tokman, S., et al. (2015) · American Journal of Respiratory and Critical Care Medicine

Frailty in Older AdultsTransplantation: Methods and Outcomes

Cited by 224

Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?

Wolters, P. J., Blackwell, T. S., Eickelberg, O., Loyd, J. E., Kaminski, N., Jenkins, G., Maher, T. M., Molina-Molina, M., Noble, P. W., Raghu, G., et al. (2018) · The Lancet Respiratory Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 196

Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β

Kitamura, H., Cambier, S., Somanath, S., Barker, T., Minagawa, S., Markovics, J., Goodsell, A., Publicover, J., Reichardt, L., Jablons, D., et al. (2011) · Journal of Clinical Investigation

Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseases

Cited by 189

Mast Cell IL-6 Improves Survival from Klebsiella Pneumonia and Sepsis by Enhancing Neutrophil Killing

Sutherland, R. E., Olsen, J. S., McKinstry, A., Villalta, S. A., & Wolters, P. J. (2008) · The Journal of Immunology

Inflammation biomarkers and pathwaysSepsis Diagnosis and Treatment

Cited by 155

miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis

Disayabutr, S., Kim, E. K., Cha, S.-I., Green, G., Naikawadi, R. P., Jones, K. D., Golden, J. A., Schroeder, A., Matthay, M. A., Kukreja, J., et al. (2016) · PLOS ONE

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 136

TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis

Sun, T., Huang, Z., Liang, W.-C., Yin, J., Lin, W. Y., Wu, J., Vernes, J.-M., Lutman, J., Caplazi, P., Jeet, S., et al. (2021) · Science Translational Medicine

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 134

Prevalence and clinical significance of circulating autoantibodies in idiopathic pulmonary fibrosis

Lee, J. S., Kim, E. J., Lynch, K. L., Elicker, B., Ryerson, C. J., Katsumoto, T. R., Shum, A. K., Wolters, P. J., Cerri, S., Richeldi, L., et al. (2013) · Respiratory Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSystemic Sclerosis and Related Diseases

Cited by 100

Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF

Decaris, M. L., Schaub, J. R., Chen, C., Cha, J., Lee, G. G., Rexhepaj, M., Ho, S. S., Rao, V., Marlow, M. M., Kotak, P., et al. (2021) · Respiratory Research

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisCell Adhesion Molecules Research

Cited by 94

Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease

Minagawa, S., Lou, J., Seed, R. I., Cormier, A., Wu, S., Cheng, Y., Murray, L., Tsui, P., Connor, J., Herbst, R., et al. (2014) · Science Translational Medicine

Cell Adhesion Molecules ResearchChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 90

Molecular programs of fibrotic change in aging human lung

Lee, S., Islam, M. N., Boostanpour, K., Aran, D., Jin, G., Christenson, S., Matthay, M. A., Eckalbar, W. L., DePianto, D. J., Arron, J. R., et al. (2021) · Nature Communications

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 78

Mortality Risk Prediction in Scleroderma-Related Interstitial Lung Disease

Morisset, J., Vittinghoff, E., Elicker, B. M., Hu, X., Le, S., Ryu, J. H., Jones, K. D., Haemel, A., Golden, J. A., Boin, F., et al. (2017) · Chest

Systemic Sclerosis and Related DiseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 77

Invariant natural killer T cells coordinate removal of senescent cells

Arora, S., Thompson, P. J., Wang, Y., Bhattacharyya, A., Apostolopoulou, H., Hatano, R., Naikawadi, R. P., Shah, A., Wolters, P. J., Koliwad, S., et al. (2021) · Med

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 77

The performance of the GAP model in patients with rheumatoid arthritis associated interstitial lung disease

Morisset, J., Vittinghoff, E., Lee, B. Y., Tonelli, R., Hu, X., Elicker, B. M., Ryu, J. H., Jones, K. D., Cerri, S., Manfredi, A., et al. (2017) · Respiratory Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 65

Protease-Activated Receptor 2, Dipeptidyl Peptidase I, and Proteases Mediate Clostridium difficile Toxin A Enteritis

Cottrell, G. S., Amadesi, S., Pikios, S., Camerer, E., Willardsen, J. A., Murphy, B. R., Caughey, G. H., Wolters, P. J., Coughlin, S. R., Peterson, A., et al. (2007) · Gastroenterology

Clostridium difficile and Clostridium perfringens researchBlood Coagulation and Thrombosis Mechanisms

Cited by 56