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Transforming Growth Factor Beta2 Promotes Migration and Inhibits the Proliferation of Gastric Cancer Cells by Regulating the pSmad2/3‐NDRG1 Signaling Pathway

He, F., Chen, X., Zhu, Y., Pang, H., Li, Z., Liang, P., Jin, T., Chen, Z., Chen, Z., Hu, J., et al. (2025) · MedComm · doi:10.1002/mco2.70148 · Cited by 5 · see citing works

Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated in mouse and cynomolgus monkey toxicology studies

Mitra, M. S., Halpern, W., Lepherd, M. L., Corpuz, J., Adedeji, A. O., Yadav, R., Duarte, I., Sun, T., Arron, J. R., Turley, S. J., et al. (2025) · Toxicological Sciences · doi:10.1093/toxsci/kfaf059 · Cited by 5 · see citing works

mRNA sequencing reveals the distinct gene expression and biological functions in cardiac fibroblasts regulated by recombinant fibroblast growth factor 2

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Beyond circulating B cells: Characteristics and role of tissue-infiltrating B cells in systemic sclerosis

Maître, M. L., Guerrier, T., Sanges, S., Chepy, A., Collet, A., & Launay, D. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103782 · Cited by 5 · see citing works

Engineered fibrotic liver-targeted truncated transforming growth factor β receptor type II variant for superior anti-liver fibrosis therapy

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Antifibrotic therapeutic strategies in systemic sclerosis: Critical role of the Wnt/β-catenin and TGF-β signal transduction pathways as potential targets

Bagheri, L., Javanbakht, M., Malekian, S., Ghahderijani, B. H., Taghipour, S., Tanha, F. D., Ranjkesh, M. H., Cegolon, L., & Zhao, S. G. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177607 · Cited by 4 · see citing works

ISG15 deficiency in hepatic stellate cells promotes TGFβ2-induced liver fibrosis by counteracting CREB1 ISGylation

Yuan, Y., Li, J., Rao, D., Lu, X., Chen, M., Chen, X., Long, X., Zhang, B., Liang, H., Chen, Q., et al. (2025) · Gut · doi:10.1136/gutjnl-2025-335327 · Cited by 4 · see citing works

TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15

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The Tolerance Model of Non-Inflammatory Immune Competence in Acute Pediatric Malnutrition: Origins, Evidence, Test of Fitness and Growth Potential

Woodward, B. D., Hillyer, L. M., & Monk, J. M. (2023) · Nutrients · doi:10.3390/nu15234922 · Cited by 4 · see citing works

Contribution of the TGFβ signaling pathway to growth of Pacific oyster (Crassostrea gigas)

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Targeting PYK2, entrectinib allays anterior subcapsular cataracts in mice by regulating TGFβ2 signaling pathway

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Antiproliferative agent attenuates postthrombotic vein wall remodeling in murine and human subjects

Pu, H., Lei, J., Du, G., Huang, Q., Qiu, P., Liu, J., Li, C., Ying, X., Liu, K., Xu, Z., et al. (2024) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2024.09.012 · Cited by 4 · see citing works

Unraveling the role of long non-coding RNAs in chronic heat stress-induced muscle injury in broilers

Liu, Z., Liu, Y., Xing, T., Li, J., Zhang, L., Zhao, L., Jiang, Y., & Gao, F. (2024) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-024-01093-6 · Cited by 4 · see citing works

Eosinophilic Fasciitis and Morphea Share Gene Signatures of Inflammatory Cell Death, Self-DNA Recognition, and Enhanced Jak/Signal Transducer and Activator of Transcription Signaling

Crisler, W. J., Rowley, R., Oke, O. H., Steuart, S. J., Modi, M. M., Davis, D. L., Chen, C., Gray, L., Teague, J. E., Zhan, Q., et al. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2025.05.023 · Cited by 6 · see citing works

The Development and Characterization of a Highly Sensitive Mature TGFβ3 Assay to Evaluate Anti-TGFβ3 Target Engagement

Setiadi, A., Sperinde, G. V., Cheu, M., Liang, W., Lin, W., Mahood, C., & Fischer, S. K. (2023) · The AAPS Journal · doi:10.1208/s12248-023-00785-7 · Cited by 4 · see citing works

iPSCs engrafted in allogeneic hosts without immunosuppression induce donor-specific tolerance to secondary allografts

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Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Xia, J., Wang, W. Y., Jacobs, K. A., Maniar, K., Lin, D., Jarman, E. H., Matera, D. L., Loesel, K., Davidson, C. D., Hiraki, H. L., et al. (2026) · Advanced Science · doi:10.1002/advs.202510448 · Cited by 3 · see citing works

Fibrosis mechanisms and updates in potential therapeutic targets in systemic sclerosis

Han, X., Wang, X., Huang, J., & Yang, J. Y. (2025) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2025.152811 · Cited by 3 · see citing works

Construction of a HSC activation-related lncRNA–miRNA–mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

Wan, K., Zhou, Q., Feng, R., Liu, T., Chang, F., Pang, X., Li, Z., & Zhou, Q. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2025.1640326 · Cited by 3 · see citing works

Cardiomyocyte-derived TGFB3 attenuates cardiac fibrosis and preserves cardiac function in heart failure

Xuan, J., Zhou, J., Huang, Y., Huang, M., Pu, S., Fang, L., Chen, Y., & Xue, J. (2026) · Scientific Reports · doi:10.1038/s41598-026-42367-5 · Cited by 3 · see citing works

Lentiviral-Mediated Expression of a Novel Transforming Growth Factor-β (TGF-β) Inhibitor Peptibody Therapeutically Mitigates Established Liver Fibrosis by Modulating Inflammation and Inducing Metabolic Reprogramming

la Colla, A. B., Cámara, C. A., Rodríguez, T. M., Echarte, S. M., Alomar, M. L., Chisari, A. N., & Dewey, R. A. (2026) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.5c00817 · Cited by 3 · see citing works

Inflammation-driven mitochondrial dysfunction and ROS accumulation orchestrate pulmonary fibrotic remodeling in sepsis

Zhong, Z., Wu, K., Wang, J., Chen, G., Luo, H., Chen, G., Sun, C., Guo, D., Li, L., Li, L., et al. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104225 · Cited by 3 · see citing works

TGFβ2 mediates oxidative stress–induced epithelial-to-mesenchymal transition of bladder smooth muscle

Geng, J., Zhang, X., Zhang, Y., Meng, X., Sun, J., Zhou, B., & Ma, J. (2024) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-024-00864-9 · Cited by 3 · see citing works

Interplay of ST2 downregulation and inflammatory dysregulation in hypertrophic cardiomyopathy pathogenesis

Cao, X., Wang, H.-W., Hu, Z., Ma, W., Ding, P., Sun, H., & Guo, X.-Y. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1511415 · Cited by 3 · see citing works

Low expression of TGF ‐β2 and matrilin2 in human aqueous humour with acute primary angle closure

Wang, L., Xu, Z., Hong, Y., Liu, Y., Zhang, X., Feng, Q., Zhang, D., Chen, K., Yiming, G. H., Li, X., et al. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.18111 · Cited by 3 · see citing works

Latent-TGF-β has a domain swapped architecture

Jin, M., Seed, R. I., Shing, T., Wang, L., Li, J., Cheng, Y., & Nishimura, S. L. (2025) · Nature Communications · doi:10.1038/s41467-025-65465-w · Cited by 3 · see citing works

Role of progesterone action in inguinal hernia formation via skeletal muscle fibrosis and atrophy

You, T., Zandigohar, M., Potluri, T., Piehl, N., Coon, J. S., Baker, E., Kafali, M., Dai, Y. D., Stulberg, J. J., Escobar, D., et al. (2025) · JCI Insight · doi:10.1172/jci.insight.193208 · Cited by 2 · see citing works

Med13 and Med13L: Critical redundant players in basal cardiac function and gene expression

Henry, K. M., Gardner, R. N., Oppman, A. M., Daneshgar, N., Rosales, M., Martins, I., Baskin, K. K., & Grueter, C. E. (2025) · Journal of Molecular and Cellular Cardiology Plus · doi:10.1016/j.jmccpl.2025.100481 · Cited by 2 · see citing works

Extracellular Matrix and Fibroblast Activation in Lymphangioleiomyomatosis

Mukhitov, A. R., Evans, J. F., Han, T., Ledwell, O. A., Rue, R. W., Obraztsova, K., Lin, S. M., Basil, M. C., Cantu, E., Tang, Y., et al. (2025) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2025-0237oc · Cited by 2 · see citing works

Persistent tissue regeneration and transforming growth factor-β induced fibrosis in the masseter muscle of mdx5Cv mice

Ait‐Lounis, A., Neff, L. A., Kiliaridis, S., Wehrle‐Haller, B., Dorchies, O. M., & Antonarakis, G. S. (2025) · Scientific Reports · doi:10.1038/s41598-025-17154-3 · Cited by 2 · see citing works

Precision Target Discovery for Migraine: An Integrated GWAS-eQTL-PheWAS Pipeline

Liu, X., Liu, Q., Zhu, H., Zhou, X. B., Li, X., Hu, M., Peng, F., Ji, J., & Yang, S. (2025) · Molecules · doi:10.3390/molecules30193921 · Cited by 2 · see citing works

Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review

Wu, M., Zhang, J., Xiong, N., Ma, Y., Yong, L., Liu, H., & Guo, Q. (2026) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.70705 · Cited by 2 · see citing works

Non-immune factors cause prolonged myofibroblast phenotype in implanted synthetic heart valve scaffolds

Snyder, Y., Mann, F. A., Middleton, J. R., Murashita, T., Carney, J. P., Bianco, R. W., & Jana, S. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102323 · Cited by 2 · see citing works

Isoform-selective TGF-β3 inhibition for systemic sclerosis

Sun, T., Heiden, J. A. V., Gao, X., Yin, J., Uttarwar, S., Liang, W., Jia, G., Yadav, R., Huang, Z., Mitra, M. S., et al. (2024) · Med · doi:10.1016/j.medj.2023.12.011 · Cited by 32 · see citing works

An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis

Jackson, J., Streich, F. C., Pal, A., Coricor, G., Boston, C., Brueckner, C., Canonico, K., Chapron, C., Cote, S. M., Dagbay, K. B., et al. (2024) · Science Signaling · doi:10.1126/scisignal.adn6052 · Cited by 28 · see citing works

Thrombofibrosis: inherited thrombophilia as a cause of significant liver fibrosis

Ezcurra, I., Fortea, J. I., Puente, Á., Cuadrado, A., Garciá, I., Gonzalez, F. J., Pellón, R., Sanchez, S., Crespo, J., Acebo, M., et al. (2020) · Journal of Hepatology · doi:10.1016/s0168-8278(20)31507-5

Systematic Comparison of the TGF-β Isoforms in Normal Dermal and Lung Fibroblasts Identifies TGF-β2 and TGF-β3 as Priority Targets in Tissue Fibrosis

Badyal, R., Kohlen, B., Keen, K. J., Dunne, J. V., & Hackett, T. (2026) · Cells · doi:10.3390/cells15080671

TGF-β-induced fibrosis: A review on the underlying mechanism and potential therapeutic strategies

Ong, C. H., Tham, C. L., Harith, H. H., Firdaus, N., & Israf, D. A. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2021.174510 · Cited by 189 · see citing works