Varki, Ajit

Heparin inhibits the flow adhesion of sickle red blood cells to P-selectin

Matsui, N. M., Varki, A., & Embury, S. H. (2002) · Blood

Hemoglobinopathies and Related DisordersBlood properties and coagulation

Cited by 123

Human-specific expression of Siglec-6 in the placenta

Brinkman-Van der Linden, E. C. M., Hurtado-Ziola, N., Hayakawa, T., Wiggleton, L., Benirschke, K., Varki, A., & Varki, N. (2007) · Glycobiology

Glycosylation and Glycoproteins ResearchReproductive System and Pregnancy

Cited by 123

Endothelial Heparan Sulfate Proteoglycans That Bind to L-Selectin Have Glucosamine Residues with Unsubstituted Amino Groups

Norgard-Sumnicht, K., & Varki, A. (1995) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchCell Adhesion Molecules Research

Cited by 123

Host Adaptation of a Bacterial Toxin from the Human Pathogen Salmonella Typhi

Deng, L., Song, J., Gao, X., Wang, J., Yu, H., Chen, X., Varki, N., Naito-Matsui, Y., Galán, J. E., & Varki, A. (2014) · Cell

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 120

Human species-specific loss of CMP- N -acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

Kawanishi, K., Dhar, C., Do, R., Varki, N., Gordts, P. L. S. M., & Varki, A. (2019) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchAtherosclerosis and Cardiovascular Diseases

Cited by 94

Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation

Secundino, I., Lizcano, A., Roupé, K. M., Wang, X., Cole, J. N., Olson, J., Ali, S. R., Dahesh, S., Amayreh, L. K., Henningham, A., et al. (2016) · Journal of Molecular Medicine

Glycosylation and Glycoproteins ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 92

Identification of a variant of mucolipidosis III (pseudo-Hurler polydystrophy): a catalytically active N-acetylglucosaminylphosphotransferase that fails to phosphorylate lysosomal enzymes.

Varki, A. P., Reitman, M. L., & Kornfeld, S. (1981) · Proceedings of the National Academy of Sciences

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 89

Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood

Deng, L., Bensing, B. A., Thamadilok, S., Yu, H., Lau, K., Chen, X., Ruhl, S., Sullam, P. M., & Varki, A. (2014) · PLoS Pathogens

Glycosylation and Glycoproteins ResearchInfective Endocarditis Diagnosis and Management

Cited by 88

Hyaluronan digestion controls DC migration from the skin

Muto, J., Morioka, Y., Yamasaki, K., Kim, M., Garcia, A., Carlin, A. F., Varki, A., & Gallo, R. L. (2014) · Journal of Clinical Investigation

Proteoglycans and glycosaminoglycans researchMast cells and histamine

Cited by 84

Modulation of Glycan Recognition by Clustered Saccharide Patches

Cohen, M., & Varki, A. P. (2014) · International Review of Cell and Molecular Biology

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 84

Why Is N-Glycolylneuraminic Acid Rare in the Vertebrate Brain?

Davies, L. R. L., & Varki, A. (2013) · Topics in Current Chemistry

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 80

Sexual selection by female immunity against paternal antigens can fix loss of function alleles

Ghaderi, D., Springer, S. A., Ma, F., Cohen, M., Secrest, P., Taylor, R. E., Varki, A., & Gagneux, P. (2011) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsAnimal Behavior and Reproduction

Cited by 79

Intramolecular self-cleavage of polysialic acid.

Manzi, A. E., Higa, H. H., Diaz, S., & Varki, A. (1994) · Journal of Biological Chemistry

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 78

ABO blood group glycans modulate sialic acid recognition on erythrocytes

Cohen, M., Hurtado-Ziola, N., & Varki, A. (2009) · Blood

Glycosylation and Glycoproteins ResearchBlood groups and transfusion

Cited by 75

Specific inactivation of two immunomodulatory SIGLEC genes during human evolution

Wang, X., Mitra, N., Secundino, I., Banda, K., Cruz, P., Padler-Karavani, V., Verhagen, A., Reid, C., Lari, M., Rizzi, E., et al. (2012) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchImmune Cell Function and Interaction

Cited by 72

Human-specific evolution of sialic acid targets: Explaining the malignant malaria mystery?

Varki, A., & Gagneux, P. (2009) · Proceedings of the National Academy of Sciences

Malaria Research and ControlGlycosylation and Glycoproteins Research

Cited by 62

Multiple Hepatic Receptors Cooperate to Eliminate Secretory Mucins Aberrantly Entering the Bloodstream: Are Circulating Cancer Mucins the “Tip of the Iceberg”?

Wahrenbrock, M. G., & Varki, A. (2006) · Cancer Research

Glycosylation and Glycoproteins ResearchProteoglycans and glycosaminoglycans research

Cited by 58

Training the next generation of biomedical investigators in glycosciences

Agre, P., Bertozzi, C., Bissell, M., Campbell, K. P., Cummings, R. D., Desai, U. R., Estes, M., Flotte, T., Fogleman, G., Gage, F., et al. (2016) · Journal of Clinical Investigation

Glycosylation and Glycoproteins ResearchHealth and Medical Research Impacts

Cited by 34

Account for the 'dark matter' of biology

Varki, A. (2013) · Nature

Philosophy of Biology and Scientific ExplanationEvolution and Genetic Dynamics

Cited by 14