Herz, Joachim

Neuronal LRP1 Functionally Associates with Postsynaptic Proteins and Is Required for Normal Motor Function in Mice

May, P., Rohlmann, A., Bock, H. H., Zurhove, K., Marth, J. D., Schomburg, E. D., Noebels, J. L., Beffert, U., Sweatt, J. D., Weeber, E. J., et al. (2004) · Molecular and Cellular Biology

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 236

Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination

Bock, H. H., Jossin, Y., Liu, P., Förster, E., May, P., Goffinet, A. M., & Herz, J. (2003) · Journal of Biological Chemistry

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 213

Receptor Clustering Is Involved in Reelin Signaling

Strasser, V., Fasching, D., Hauser, C., Mayer, H., Bock, H. H., Hiesberger, T., Herz, J., Weeber, E. J., Sweatt, J. D., Pramatarova, A., et al. (2004) · Molecular and Cellular Biology

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 193

LRP4 mutations alter Wnt/β-catenin signaling and cause limb and kidney malformations in Cenani–Lenz syndrome

Li, Y., Pawlik, B., Elcioglu, N., Aglan, M., Kayserili, H., Yigit, G., Percin, F., Goodman, F., Nürnberg, G., Cenani, A., et al. (2010) · The American Journal of Human Genetics

Congenital limb and hand anomaliesWnt/β-catenin signaling in development and cancer

Cited by 171

More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration

Lane-Donovan, C., Philips, G. T., & Herz, J. (2014) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 158

ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease

Lane-Donovan, C., & Herz, J. (2017) · Trends in Endocrinology & Metabolism

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 157

Reelin signaling antagonizes β-amyloid at the synapse

Durakoglugil, M. S., Chen, Y., White, C. L., Kavalali, E. T., & Herz, J. (2009) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 153

LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling

Terrand, J., Bruban, V., Zhou, L., Gong, W., El Asmar, Z., May, P., Zurhove, K., Haffner, P., Philippe, C., Woldt, E., et al. (2009) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipid metabolism and biosynthesis

Cited by 143

Differential glycosylation regulates processing of lipoprotein receptors by γ-secretase

May, P., Bock, H. H., Nimpf, J., & Herz, J. (2003) · Journal of Biological Chemistry

Glycosylation and Glycoproteins ResearchAlzheimer's disease research and treatments

Cited by 142

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice

Johnson, E. B., Hammer, R. E., & Herz, J. (2005) · Human Molecular Genetics

Congenital limb and hand anomaliesDevelopmental Biology and Gene Regulation

Cited by 141

Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission

Bal, M., Leitz, J., Reese, A. L., Ramirez, D. M. O., Durakoglugil, M., Herz, J., Monteggia, L. M., & Kavalali, E. T. (2013) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 131

Emerging topics in Reelin function

Förster, E., Bock, H. H., Herz, J., Chai, X., Frotscher, M., & Zhao, S. (2010) · European Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal Signaling

Cited by 130

Signaling through LRP1: Protection from atherosclerosis and beyond

Boucher, P., & Herz, J. (2011) · Biochemical Pharmacology

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 122

Functional Dissection of Reelin Signaling by Site-Directed Disruption of Disabled-1 Adaptor Binding to Apolipoprotein E Receptor 2: Distinct Roles in Development and Synaptic Plasticity

Beffert, U., Durudas, A., Weeber, E. J., Stolt, P. C., Giehl, K. M., Sweatt, J. D., Hammer, R. E., & Herz, J. (2006) · The Journal of Neuroscience

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 121

The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain

Carlo, A.-S., Gustafsen, C., Mastrobuoni, G., Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M., Nykjaer, A., Herz, J., Heeren, J., et al. (2013) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 117

Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes

Stolt, P. C., Jeon, H., Song, H. K., Herz, J., Eck, M. J., & Blacklow, S. C. (2003) · Structure

Protein Kinase Regulation and GTPase SignalingAxon Guidance and Neuronal Signaling

Cited by 117

Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice

Lane-Donovan, C., Wong, W. M., Durakoglugil, M. S., Wasser, C. R., Jiang, S., Xian, X., & Herz, J. (2016) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 115

Essential Role of the Apolipoprotein E Receptor-2 in Sperm Development

Andersen, O. M., Yeung, C.-H., Vorum, H., Wellner, M., Andreassen, T. K., Erdmann, B., Mueller, E.-C., Herz, J., Otto, A., Cooper, T. G., et al. (2003) · Journal of Biological Chemistry

Sperm and Testicular FunctionReproductive Biology and Fertility

Cited by 112

Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses

Wasser, C. R., & Herz, J. (2017) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchAxon Guidance and Neuronal Signaling

Cited by 111

Apolipoprotein E Receptors Are Required for Reelin-induced Proteasomal Degradation of the Neuronal Adaptor Protein Disabled-1

Bock, H. H., Jossin, Y., May, P., Bergner, O., & Herz, J. (2004) · Journal of Biological Chemistry

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 102

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease

Xian, X., Pohlkamp, T., Durakoglugil, M. S., Wong, C. H., Beck, J. K., Lane-Donovan, C., Plattner, F., & Herz, J. (2018) · eLife

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 98

Reelin protects against amyloid β toxicity in vivo

Lane-Donovan, C., Philips, G. T., Wasser, C. R., Durakoglugil, M. S., Masiulis, I., Upadhaya, A., Pohlkamp, T., Coskun, C., Kotti, T., Steller, L., et al. (2015) · Science Signaling

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 96

The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease

Lane-Donovan, C., & Herz, J. (2017) · Journal of Lipid Research

Alzheimer's disease research and treatmentsNeurogenesis and neuroplasticity mechanisms

Cited by 94

Functional Roles of the Interaction of APP and Lipoprotein Receptors

Pohlkamp, T., Wasser, C. R., & Herz, J. (2017) · Frontiers in Molecular Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 92