Reelin protects against amyloid β toxicity in vivo
Open accessAbstract
Reelin prevents the deleterious effects of amyloid β on synaptic transmission, learning, and memory.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Adult loss of Reelin does not cause significant cognitive impairment.
“adult loss of Reelin does not cause significant cognitive impairment”
From ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease (2017) · cites this paper as [42]
Adult loss of Reelin and ApoE receptor signaling in mice is well-tolerated in the absence of amyloid pathology, likely due to homeostatic regulation and compensation by other neuromodulatory mechanisms.
“adult loss of Reelin and ApoE receptor signaling in mice is well-tolerated in the absence of amyloid pathology, likely due to homeostatic regulation and compensation by other neuromodulatory mechanisms [42].”
From ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease (2017) · cites this paper as [42]
Overexpression of Aβ in Reelin-deficient mice leaves them heavily impaired in the Morris Water maze task of learning and memory.
“overexpression of Aβ in Reelin-deficient mice leaves them heavily impaired in the Morris Water maze task of learning and memory [42].”
From ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease (2017) · cites this paper as [42]
A role for Reelin in several neuropsychiatric and neurodegenerative diseases, such as autism, schizophrenia, bipolar disorder, major depression, and Alzheimer's disease, has been reported.
“A role for Reelin in several neuropsychiatric and neurodegenerative diseases, such as autism, schizophrenia, bipolar disorder, major depression, and Alzheimer's disease, has been reported (reviewed in Refs.20, 22, and 49).”
From Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses (2017) · cites this paper as [49]
Learning deficits in an AD mouse model are exacerbated by loss of Reelin expression after development.
“Similarly, the learning deficits in an AD mouse model are exacerbated by loss of Reelin expression after development (49), further solidifying the protective role of Reelin in AD.”
From Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses (2017) · cites this paper as [49]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429 · see citing works
Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,949 · see citing works
Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., & Selkoe, D. J. (2002) · Nature · doi:10.1038/416535a · Cited by 4,291 · see citing works
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., & Cole, G. (1996) · Science · doi:10.1126/science.274.5284.99 · Cited by 4,210 · see citing works
Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326 · see citing works
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
the European Alzheimer's Disease Initiative Investigators, Lambert, J.-C., Heath, S., Even, G., Campion, D., Sleegers, K., Hiltunen, M., Combarros, O., Zelenika, D., Bullido, M. J., et al. (2009) · Nature Genetics · doi:10.1038/ng.439 · Cited by 2,234 · see citing works
Genetic enhancement of learning and memory in mice
Tang, Y., Shimizu, E., Dubé, G., Rampon, C., Kerchner, G. A., Zhuo, M., Liu, G., & Tsien, J. Z. (1999) · Nature · doi:10.1038/43432 · Cited by 1,867 · see citing works
A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748 · see citing works
Regulation of NMDA receptor trafficking by amyloid-β
Snyder, E. M., Nong, Y., Almeida, C. G., Paul, S., Moran, T., Choi, E. Y., Nairn, A. C., Salter, M. W., Lombroso, P. J., Gouras, G. K., et al. (2005) · Nature Neuroscience · doi:10.1038/nn1503 · Cited by 1,561 · see citing works
Hayashi, S., & McMahon, A. P. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0597 · Cited by 1,347 · see citing works
Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., & Herz, J. (1999) · Cell · doi:10.1016/s0092-8674(00)80782-5 · Cited by 1,261 · see citing works
Self-citationKawarabayashi, T., Younkin, L. H., Saido, T. C., Shoji, M., Ashe, K. H., & Younkin, S. G. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-02-00372.2001 · Cited by 1,053 · see citing works
Hiesberger, T., Trommsdorff, M., Howell, B. W., Goffinet, A., Mumby, M. C., Cooper, J. A., & Herz, J. (1999) · Neuron · doi:10.1016/s0896-6273(00)80861-2 · Cited by 916 · see citing works
Self-citationReelin Is a Ligand for Lipoprotein Receptors
D'Arcangelo, G., Homayouni, R., Keshvara, L., Rice, D. S., Sheldon, M., & Curran, T. (1999) · Neuron · doi:10.1016/s0896-6273(00)80860-0 · Cited by 808 · see citing works
Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease
Holtzman, D. M., Herz, J., & Bu, G. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006312 · Cited by 782 · see citing works
Self-citationA decrease of reelin expression as a putative vulnerability factor in schizophrenia
Impagnatiello, F., Guidotti, A. R., Pesold, C., Dwivedi, Y., Caruncho, H. J., Pisu, M. G., Uzunov, D. P., Smalheiser, N. R., Davis, J. M., Pandey, G. N., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15718 · Cited by 753 · see citing works
The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease
Westerman, M. A., Cooper-Blacketer, D., Mariash, A., Kotilinek, L., Kawarabayashi, T., Younkin, L. H., Carlson, G. A., Younkin, S. G., & Ashe, K. H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-05-01858.2002 · Cited by 714 · see citing works
Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning
Weeber, E. J., Beffert, U., Jones, C., Christian, J. M., Förster, E., Sweatt, J. D., & Herz, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205147200 · Cited by 623 · see citing works
Self-citationGranule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy
Houser, C. R. (1990) · Brain Research · doi:10.1016/0006-8993(90)91601-c · Cited by 604 · see citing works
Reelin Binds α3β1 Integrin and Inhibits Neuronal Migration
Dulabon, L., Olson, E. C., Taglienti, M. G., Eisenhuth, S., McGrath, B., Walsh, C. A., Kreidberg, J. A., & Anton, E. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)00007-6 · Cited by 577 · see citing works
Reelin promoter hypermethylation in schizophrenia
Grayson, D. R., Jia, X., Chen, Y., Sharma, R. P., Mitchell, C. P., Guidotti, A., & Costa, E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503736102 · Cited by 553 · see citing works
Trommsdorff, M., Borg, J., Margolis, B. L., & Herz, J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.50.33556 · Cited by 540 · see citing works
Self-citationFalconer, D. S. (1951) · Journal of Genetics · doi:10.1007/bf02996215 · Cited by 539 · see citing works
Modulation of NMDA Receptor- Dependent Calcium Influx and Gene Expression Through EphB Receptors
Takasu, M. A., Dalva, M. B., Zigmond, R. E., & Greenberg, M. E. (2002) · Science · doi:10.1126/science.1065983 · Cited by 497 · see citing works
Human Apolipoprotein E Receptor 2
Kim, D.-H., Iijima, H., Goto, K., Sakai, J., Ishii, H., Kim, H.-J., Suzuki, H., Kondo, H., Saeki, S., & Yamamoto, T. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.14.8373 · Cited by 384 · see citing works
Chen, Y., Durakoglugil, M. S., Xian, X., & Herz, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914984107 · Cited by 368 · see citing works
Self-citationReelin Activates Src Family Tyrosine Kinases in Neurons
Bock, H. H., & Herz, J. (2003) · Current Biology · doi:10.1016/s0960-9822(02)01403-3 · Cited by 355 · see citing works
Self-citationReelin-mediated Signaling Locally Regulates Protein Kinase B/Akt and Glycogen Synthase Kinase 3β
Beffert, U., Morfini, G., Bock, H. H., Reyna, H., Brady, S. T., & Herz, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209205200 · Cited by 306 · see citing works
Self-citationHeinrich, C., Nitta, N., Flubacher, A., Müller, M., Fahrner, A., Kirsch, M., Freiman, T. M., Suzuki, F., Depaulis, A., Frotscher, M., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5516-05.2006 · Cited by 303 · see citing works
Self-citationFyn Tyrosine Kinase Is a Critical Regulator of Disabled-1 during Brain Development
Arnaud, L., Ballif, B. A., Förster, E., & Cooper, J. A. (2003) · Current Biology · doi:10.1016/s0960-9822(02)01397-0 · Cited by 283 · see citing works
The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons
Niu, S., Yabut, O., & D'Arcangelo, G. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1917-08.2008 · Cited by 266 · see citing works
Groc, L., Choquet, D., Stephenson, F. A., Verrier, D., Manzoni, O. J., & Chavis, P. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1772-07.2007 · Cited by 225 · see citing works
The phenotypic characteristics of heterozygous reeler mouse
Tueting, P. A., Costa, E., Dwivedi, Y. K., Guidotti, A., Impagnatiello, F., Manev, R. M., & Pesold, C. (1999) · Neuroreport · doi:10.1097/00001756-199904260-00032 · Cited by 221 · see citing works
Reelin expression and glycosylation patterns are altered in Alzheimer’s disease
Botella-López, A., Burgaya, F., Gavín, R., García-Ayllón, M. S., Gómez-Tortosa, E., Peña-Casanova, J., Ureña, J. M., Del Río, J. A., Blesa, R., Soriano, E., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601279103 · Cited by 221 · see citing works
Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth
Hoe, H.-S., Lee, K. J., Carney, R. S. E., Lee, J., Markova, A., Lee, J.-Y., Howell, B. W., Hyman, B. T., Pak, D. T. S., Bu, G., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4872-08.2009 · Cited by 219 · see citing works
Suzuki, F., Junier, M., Guilhem, D., Sørensen, J. C. H., & Onteniente, B. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00463-f · Cited by 202 · see citing works
Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice
QIU, S., KORWEK, K., PRATTDAVIS, A., PETERS, M., BERGMAN, M., & WEEBER, E. (2006) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2005.11.001 · Cited by 202 · see citing works
Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice
Gordon, M. N., King, D. L., Diamond, D. M., Jantzen, P. T., Boyett, K. W., Hope, C. E., Hatcher-Martin, J. M., DiCarlo, G., Gottschall, W. P. E., Morgan, D., et al. (2001) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00249-9 · Cited by 199 · see citing works
Receptor Clustering Is Involved in Reelin Signaling
Strasser, V., Fasching, D., Hauser, C., Mayer, H., Bock, H. H., Hiesberger, T., Herz, J., Weeber, E. J., Sweatt, J. D., Pramatarova, A., et al. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.3.1378-1386.2004 · Cited by 193 · see citing works
Self-citationDisabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1
Homayouni, R., Rice, D. S., Sheldon, M., & Curran, T. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07507.1999 · Cited by 184 · see citing works
Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density
Rogers, J. T., Rusiana, I., Trotter, J., Zhao, L., Donaldson, E., Pak, D. T. S., Babus, L. W., Peters, M., Banko, J. L., Chavis, P., et al. (2011) · Learning & Memory · doi:10.1101/lm.2153511 · Cited by 181 · see citing works
LRP8-Reelin-regulated neuronal enhancer signature underlying learning and memory formation
Telese, F., Ma, Q., Perez, P. M., Notani, D., Oh, S., Li, W., Comoletti, D., Ohgi, K. A., Taylor, H., & Rosenfeld, M. G. (2015) · Neuron · doi:10.1016/j.neuron.2015.03.033 · Cited by 166 · see citing works
Reelin signaling antagonizes β-amyloid at the synapse
Durakoglugil, M. S., Chen, Y., White, C. L., Kavalali, E. T., & Herz, J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908176106 · Cited by 153 · see citing works
Self-citationγ-Secretase Limits the Inflammatory Response Through the Processing of LRP1
Zurhove, K., Nakajima, C., Herz, J., Bock, H. H., & May, P. (2008) · Science Signaling · doi:10.1126/scisignal.1164263 · Cited by 145 · see citing works
Self-citationKocherhans, S., Madhusudan, A., Doehner, J., Breu, K. S., Nitsch, R. M., Fritschy, J.-M., & Knuesel, I. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0418-10.2010 · Cited by 132 · see citing works
Utsunomiya-Tate, N., Kubo, K.-I., Tate, S.-I., Kainosho, M., Katayama, E., Nakajima, K., & Mikoshiba, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.160272497 · Cited by 131 · see citing works
Pujadas, L., Rossi, D., Andrés, R., Teixeira, C. M., Serra-Vidal, B., Parcerisas, A., Maldonado, R., Giralt, E., Carulla, N., & Soriano, E. (2014) · Nature Communications · doi:10.1038/ncomms4443 · Cited by 129 · see citing works
Sinagra, M., Verrier, D., Frankova, D., Korwek, K. M., Blahos, J., Weeber, E. J., Manzoni, O. J., & Chavis, P. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1757-05.2005 · Cited by 128 · see citing works
Levenga, J., Krishnamurthy, P., Rajamohamedsait, H. B., Wong, H., Franke, T. F., Cain, P., Sigurdsson, E. M., & Hoeffer, C. A. (2013) · Acta Neuropathologica Communications · doi:10.1186/2051-5960-1-34 · Cited by 128 · see citing works
Hoe, H.-S., Wessner, D., Beffert, U., Becker, A. G., Matsuoka, Y., & Rebeck, G. W. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.21.9259-9268.2005 · Cited by 122 · see citing works
Beffert, U., Durudas, A., Weeber, E. J., Stolt, P. C., Giehl, K. M., Sweatt, J. D., Hammer, R. E., & Herz, J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4566-05.2006 · Cited by 121 · see citing works
Self-citationAlzheimer disease pathology in cognitively healthy elderly: A genome-wide study
Kramer, P. L., Xu, H., Woltjer, R. L., Westaway, S. K., Clark, D., Erten-Lyons, D., Kaye, J. A., Welsh-Bohmer, K. A., Troncoso, J. C., Markesbery, W. R., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.01.010 · Cited by 108 · see citing works
The RAD51 Family Member, RAD51L3, Is a DNA-stimulated ATPase That Forms a Complex with XRCC2
Braybrooke, J. P., Spink, K. G., Thacker, J., & Hickson, I. D. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002075200 · Cited by 108 · see citing works
Bock, H. H., Jossin, Y., May, P., Bergner, O., & Herz, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401770200 · Cited by 102 · see citing works
Self-citationLeeb, C., Eresheim, C., & Nimpf, J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.529271 · Cited by 99 · see citing works
The heterozygous reeler mouse: behavioural phenotype
Podhorná, J., & Didriksen, M. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.10.033 · Cited by 97 · see citing works
Reelin deficiency causes granule cell dispersion in epilepsy
Haas, C. A., & Frotscher, M. (2010) · Experimental Brain Research · doi:10.1007/s00221-009-1948-5 · Cited by 96 · see citing works
Self-citationApoE isoform-dependent changes in hippocampal synaptic function
Korwek, K. M., Trotter, J. H., LaDu, M. J., Sullivan, P. M., & Weeber, E. J. (2009) · Molecular Neurodegeneration · doi:10.1186/1750-1326-4-21 · Cited by 89 · see citing works
Dab1 Is Required for Synaptic Plasticity and Associative Learning
Trotter, J. H., Lee, G. H., Kazdoba, T. M., Crowell, B., Domogauer, J., Mahoney, H. L., Franco, S. J., Müller, U., Weeber, E. J., & D’Arcangelo, G. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2010-13.2013 · Cited by 87 · see citing works
Rogers, J. T., Zhao, L., Trotter, J. H., Rusiana, I., Peters, M. M., Li, Q., Donaldson, E., Banko, J. L., Keenoy, K. E., Rebeck, G. W., et al. (2012) · Journal of Psychopharmacology · doi:10.1177/0269881112463468 · Cited by 87 · see citing works
Reelin, Integrin and Dab1 Interactions during Embryonic Cerebral Cortical Development
Schmid, R. S., Jo, R., Shelton, S., Kreidberg, J. A., & Anton, E. S. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi041 · Cited by 86 · see citing works
Genetic Modulation of Tau Phosphorylation in the Mouse
Brich, J., Shie, F., Howell, B. W., Li, R., Tus, K., Wakeland, E. K., Jin, L., Mumby, M. C., Churchill, G. A., Herz, J., et al. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-01-00187.2003 · Cited by 83 · see citing works
Self-citationReelin induces EphB activation
Bouché, E., Romero‐Ortega, M. I., Henkemeyer, M. J., Catchpole, T., Leemhuis, J., Frotscher, M., May, P., Herz, J., & Bock, H. H. (2013) · Cell Research · doi:10.1038/cr.2013.7 · Cited by 68 · see citing works
Self-citationThe RELN Locus in Alzheimer's Disease
Seripa, D., Matera, M. G., Franceschi, M., Daniele, A., Bizzarro, A., Rinaldi, M., Panza, F., Fazio, V. M., Gravina, C., D’Onofrio, G., et al. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-14308 · Cited by 68 · see citing works
Exogenous reelin prevents granule cell dispersion in experimental epilepsy
Müller, M. C., Osswald, M., Tinnes, S., Häussler, U., Jacobi, A., Förster, E., Frotscher, M., & Haas, C. A. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2008.12.029 · Cited by 60 · see citing works
Self-citationReelin Induces Erk1/2 Signaling in Cortical Neurons Through a Non-canonical Pathway
Lee, G. H., Chhangawala, Z., von Daake, S., Savas, J. N., Yates, J. R., Comoletti, D., & D’Arcangelo, G. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.576249 · Cited by 57 · see citing works
Ognibene, E., Adriani, W., Granstrem, O., Pieretti, S., & Giovanni Laviola, A. (2006) · Brain Research · doi:10.1016/j.brainres.2006.11.007 · Cited by 55 · see citing works
Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning
Wasser, C. R., Masiulis, I., Durakoglugil, M. S., Lane-Donovan, C., Xian, X., Beffert, U., Agarwala, A., Hammer, R. E., & Herz, J. (2014) · Science Signaling · doi:10.1126/scisignal.2005438 · Cited by 48 · see citing works
Self-citationEpilepsy-Induced Motility of Differentiated Neurons
Chai, X., Münzner, G., Zhao, S., Tinnes, S., Kowalski, J., Häussler, U., Young, C. C., Haas, C. A., & Frotscher, M. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht067 · Cited by 39 · see citing works
Self-citationNiwa‐Kawakita, M., Abramowski, V., Kalamarides, M., Thomas, G. D., & Giovannini, M. (2000) · genesis · doi:10.1002/(sici)1526-968x(200002)26:2 · Cited by 22 · see citing works
Dab1 binds to Fe65 and diminishes the effect of Fe65 or LRP1 on APP processing
Kwon, O. Y., Hwang, K., Kim, J.-A., Kim, K., Kwon, I. C., Song, H. K., & Jeon, H. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22738 · Cited by 18 · see citing works
NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice
Isosaka, T., Hattori, K., & Yagi, T. (2006) · Brain Research · doi:10.1016/j.brainres.2005.12.049 · Cited by 13 · see citing works
Flagged first, then by citations
1 of the 73 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Jossin, Y. (2020) · Biomolecules · doi:10.3390/biom10060964 · Cited by 208 · see citing works
Lymphoangiocrine signals promote cardiac growth and repair
Liu, X., de la Cruz, E., Gu, X., Bálint, L., Oxendine, M., Terrones, T. S., Ma, W., Kuo, H., Lantz, C. W., Bansal, T., et al. (2020) · Nature · doi:10.1038/s41586-020-2998-x · Cited by 203 · see citing works
Self-citationReelin and neuropsychiatric disorders
Ishii, K., Kubo, K.-I., & Nakajima, K. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00229 · Cited by 185 · see citing works
Shaping Synapses by the Neural Extracellular Matrix
Ferrer-Ferrer, M., & Dityatev, A. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00040 · Cited by 169 · see citing works
ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease
Lane-Donovan, C., & Herz, J. (2017) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2016.12.001 · Cited by 157 · see citing works
Self-citationNew insights into Reelin-mediated signaling pathways
Lee, G. H., & D’Arcangelo, G. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00122 · Cited by 144 · see citing works
Hinrich, A. J., Jodelka, F. M., Chang, J. L., Brutman, D., Bruno, A. M., Briggs, C. A., James, B. D., Stutzmann, G. E., Bennett, D. A., Miller, S. A., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201505846 · Cited by 127 · see citing works
Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses
Wasser, C. R., & Herz, J. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r116.766782 · Cited by 111 · see citing works
Self-citationCanonical and non-canonical Reelin signaling
Bock, H. H., & May, P. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00166 · Cited by 107 · see citing works
Self-citationThe role of APOE4 in Alzheimer’s disease: strategies for future therapeutic interventions
Hunsberger, H. C., Pinky, P. D., Smith, W., Suppiramaniam, V., & Reed, M. N. (2019) · Neuronal Signaling · doi:10.1042/ns20180203 · Cited by 94 · see citing works
The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease
Lane-Donovan, C., & Herz, J. (2017) · Journal of Lipid Research · doi:10.1194/jlr.r075507 · Cited by 94 · see citing works
Self-citationFunctional Roles of the Interaction of APP and Lipoprotein Receptors
Pohlkamp, T., Wasser, C. R., & Herz, J. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00054 · Cited by 92 · see citing works
Self-citationThe Reelin Receptors Apolipoprotein E receptor 2 (ApoER2) and VLDL Receptor
Dlugosz, P., & Nimpf, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103090 · Cited by 91 · see citing works
Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework
Mentis, A. A., Dardiotis, E., & Chrousos, G. P. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0731-7 · Cited by 82 · see citing works
Hypervulnerability of the adolescent prefrontal cortex to nutritional stress via reelin deficiency
Labouesse, M. A., Lassalle, O., Richetto, J., Iafrati, J., Weber‐Stadlbauer, U., Notter, T., Gschwind, T., Pujadas, L., Soriano, E., Reichelt, A. C., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.193 · Cited by 75 · see citing works
Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin
Ogino, H., Hisanaga, A., Kohno, T., Kondo, Y., Okumura, K., Kamei, T., Sato, T., Asahara, H., Tsuiji, H., Fukata, M., et al. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3632-16.2017 · Cited by 74 · see citing works
Ding, Y., Huang, L., Xian, X., Yuhanna, I. S., Wasser, C. R., Frotscher, M., Mineo, C., Shaul, P. W., & Herz, J. (2016) · Science Signaling · doi:10.1126/scisignal.aad5578 · Cited by 72 · see citing works
Self-citationThe Functioning of a Cortex without Layers
Guy, J., & Staiger, J. F. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00054 · Cited by 68 · see citing works
Bachmann, C., Nguyen, H., Rosenbusch, J., Pham, L., Rabe, T., Patwa, M., Sokpor, G., Seong, R. H., Ashery‐Padan, R., Mansouri, A., et al. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006274 · Cited by 70 · see citing works
Reelin: Diverse roles in central nervous system development, health and disease
Armstrong, N. C., Anderson, R. C., & McDermott, K. W. G. (2019) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2019.04.009 · Cited by 50 · see citing works
The β-amyloid peptide compromises Reelin signaling in Alzheimer’s disease
Cuchillo‐Ibáñez, I., Mata‐Balaguer, T., Balmaceda, V., Arranz, J. J., Nimpf, J., & Sáez‐Valero, J. (2016) · Scientific Reports · doi:10.1038/srep31646 · Cited by 47 · see citing works
Ampuero, E., Jury, N., Härtel, S., Marzolo, M., & van Zundert, B. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25605 · Cited by 47 · see citing works
Sakai, K., Shoji, H., Kohno, T., Miyakawa, T., & Hattori, M. (2016) · Scientific Reports · doi:10.1038/srep28636 · Cited by 46 · see citing works
NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
Pohlkamp, T., Xian, X., Wong, C. H. Y., Durakoglugil, M. S., Werthmann, G. C., Saido, T. C., Evers, B. M., White, C. L., Connor, J., Hammer, R. E., et al. (2021) · eLife · doi:10.7554/elife.72034 · Cited by 44 · see citing works
Self-citationYamakage, Y., Kato, M., Hongo, A., Ogino, H., Ishii, K., Ishizuka, T., Kamei, T., Tsuiji, H., Miyamoto, T., Oishi, H., et al. (2019) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2019.103401 · Cited by 42 · see citing works
Reelin Signaling in Neurodevelopmental Disorders and Neurodegenerative Diseases
Joly‐Amado, A., Kulkarni, N., & Nash, K. R. (2023) · Brain Sciences · doi:10.3390/brainsci13101479 · Cited by 43 · see citing works
Early onset senescence and cognitive impairment in a murine model of repeated mTBI
Schwab, N., Ju, Y., & Hazrati, L.-N. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01190-x · Cited by 39 · see citing works
Reelin in Alzheimer’s Disease, Increased Levels but Impaired Signaling: When More is Less
Cuchillo‐Ibáñez, I., Balmaceda, V., Mata‐Balaguer, T., López‐Font, I., & Sáez‐Valero, J. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-151193 · Cited by 35 · see citing works
Kounnas, M. Z., Lane‐Donovan, C., Nowakowski, D. W., Herz, J., & Comer, W. T. (2016) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1016/j.trci.2016.09.003 · Cited by 37 · see citing works
Self-citationBosch, C., Muhaisen, A., Pujadas, L., Soriano, E., & Martı́nez, A. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00138 · Cited by 34 · see citing works
Bracher-Smith, M., Leonenko, G., Baker, E., Crawford, K., Graham, A. C., Salih, D. A., Howell, B. W., Hardy, J., & Escott-Price, V. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.07.009 · Cited by 31 · see citing works
Reelin proteolysis affects signaling related to normal synapse function and neurodegeneration
Lussier, A. L., Weeber, E. J., & Rebeck, G. W. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00075 · Cited by 31 · see citing works
Regulation of Reelin functions by specific proteolytic processing in the brain
Hattori, M., & Kohno, T. (2021) · The Journal of Biochemistry · doi:10.1093/jb/mvab015 · Cited by 34 · see citing works
Reelin reverts biochemical, physiological and cognitive alterations in mouse models of Tauopathy
Rossi, D., Gruart, A., Contreras-Murillo, G., Muhaisen, A., Ávila, J., Delgado-García, J. M., Pujadas, L., & Soriano, E. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.101743 · Cited by 30 · see citing works
A key requirement for synaptic Reelin signaling in ketamine-mediated behavioral and synaptic action
Kim, J., Herz, J., Kavalali, E. T., & Monteggia, L. M. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2103079118 · Cited by 28 · see citing works
Self-citationMata‐Balaguer, T., Cuchillo‐Ibáñez, I., Calero, M., Ferrer, I., & Sáez‐Valero, J. (2018) · The FASEB Journal · doi:10.1096/fj.201700736rr · Cited by 28 · see citing works
Okugawa, E., Ogino, H., Shigenobu, T., Yamakage, Y., Tsuiji, H., Oishi, H., Kohno, T., & Hattori, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-61380-w · Cited by 29 · see citing works
Calvier, L., Demuth, G., Manouchehri, N., Wong, C. H. Y., Sacharidou, A., Mineo, C., Shaul, P. W., Monson, N. L., Kounnas, M. Z., Stüve, O., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay7675 · Cited by 30 · see citing works
Self-citationOrcinha, C., Münzner, G., Gerlach, J., Kilias, A., Follo, M., Egert, U., & Haas, C. A. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00183 · Cited by 26 · see citing works
Reelin restricts dendritic growth of interneurons in the neocortex
Hamad, M. I. K., Petrova, P., Daoud, S., Rabaya, O., Jbara, A., Melliti, N., Leifeld, J., Jakovčevski, I., Reiss, G., Herz, J., et al. (2021) · Development · doi:10.1242/dev.199718 · Cited by 25 · see citing works
Self-citationWallin, C., Luo, J., Jarvet, J., Wärmländer, S. K. T. S., & Gräslund, A. (2016) · Israel Journal of Chemistry · doi:10.1002/ijch.201600105 · Cited by 24 · see citing works
Tolar, M., Hey, J. A., Power, A., & Abushakra, S. R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052727 · Cited by 22 · see citing works
Reelin signaling modulates GABAB receptor function in the neocortex
Hamad, M. I. K., Jbara, A., Rabaya, O., Petrova, P., Daoud, S., Melliti, N., Meseke, M., Lutz, D., Petrasch‐Parwez, E., Schwitalla, J. C., et al. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.14990 · Cited by 21 · see citing works
Self-citationProtective genetic variants against Alzheimer's disease
Mariño, C., Malotaux, V., Giudicessi, A., Aguillon, D. F., Falla, D. S., Lopera, F. J., & Quiroz, Y. T. (2025) · The Lancet Neurology · doi:10.1016/s1474-4422(25)00116-4 · Cited by 20 · see citing works
Hu, C., Wang, P., Zhang, S., Ren, L., Lv, Y., Yin, R. M., & Bi, J. (2017) · Neurological Research · doi:10.1080/01616412.2017.1312805 · Cited by 21 · see citing works
Reelin changes hippocampal learning in aging and Alzheimer’s disease
Marckx, A. T., Fritschle, K., Calvier, L., & Herz, J. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113482 · Cited by 19 · see citing works
Self-citationLeifeld, J., Förster, E., Reiss, G., & Hamad, M. I. K. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.917575 · Cited by 20 · see citing works
Meseke, M., Neumüller, F. H., Brunne, B., Li, X., Anstötz, M., Pohlkamp, T., Rogalla, M. M., Herz, J., Rune, G. M., & Bender, R. A. (2018) · eNeuro · doi:10.1523/eneuro.0258-18.2018 · Cited by 19 · see citing works
Self-citationPahle, J., Muhia, M., Wagener, R. J., Tippmann, A., Bock, H. H., Graw, J., Herz, J., Staiger, J. F., Drakew, A., Kneussel, M., et al. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz196 · Cited by 20 · see citing works
Self-citationHu, H., Wan, S., Hu, Y., Wang, Q., Li, H., & Zhang, N. (2025) · Annals of Medicine · doi:10.1080/07853890.2024.2445194 · Cited by 19 · see citing works
Reduced Reelin Expression in the Hippocampus after Traumatic Brain Injury
Pozzo, V. D., Crowell, B., Briski, N., Crockett, D. P., & D’Arcangelo, G. (2020) · Biomolecules · doi:10.3390/biom10070975 · Cited by 17 · see citing works
Reive, B. S., Johnston, J. N., Sánchez-Lafuente, C. L., Zhang, L., Chang, A., Zhang, J., Allen, J., Romay-Tallón, R., Kalynchuk, L. E., & Caruncho, H. J. (2023) · Chronic Stress · doi:10.1177/24705470231164920 · Cited by 15 · see citing works
Kiroski, I., Jiang, Y., Gavrilovici, C., Gao, F., Lee, S., Scantlebury, M. H., Vandal, M., Park, S. K., Tsai, L., Teskey, G. C., et al. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa088 · Cited by 15 · see citing works
Disease-Specific Changes in Reelin Protein and mRNA in Neurodegenerative Diseases
Lidón, L., Urrea, L., Llorens, F., Gil, V., Álvarez, I., Díez-Fairén, M., Aguilar, M., Pástor, P., Zerr, I., Alcolea, D. A., et al. (2020) · Cells · doi:10.3390/cells9051252 · Cited by 14 · see citing works
Embryonic mosaic deletion of APP results in displaced Reelin-expressing cells in the cerebral cortex
Callahan, D. G., Taylor, W. M., Tilearcio, M., Cavanaugh, T., Selkoe, D. J., & Young‐Pearse, T. L. (2017) · Developmental Biology · doi:10.1016/j.ydbio.2017.03.007 · Cited by 13 · see citing works
Durakoglugil, M. S., Wasser, C. R., Wong, C. H. Y., Pohlkamp, T., Xian, X., Lane‐Donovan, C., Fritschle, K., Nästle, L., & Herz, J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0388-21.2021 · Cited by 13 · see citing works
Self-citationOrcinha, C. R., Kilias, A., Paschen, E., Follo, M., & Haas, C. A. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.730811 · Cited by 12 · see citing works
Hamad, M. I. K., Daoud, S., Petrova, P., Rabaya, O., Jbara, A., Houqani, S. A., BaniYas, S., Alblooshi, M., Almheiri, A., Nakhal, M. M., et al. (2024) · Development · doi:10.1242/dev.202449 · Cited by 12 · see citing works
Self-citationThe Inflammation-Induced Dysregulation of Reelin Homeostasis Hypothesis of Alzheimer’s Disease
Reive, B. S., Lau, V. Z., Sánchez-Lafuente, C. L., Henri‐Bhargava, A., Kalynchuk, L. E., Tremblay, M., & Caruncho, H. J. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240088 · Cited by 15 · see citing works
Valderrama-Mantilla, A. I., Martín-Cuevas, C., Gómez-Garrido, A., Morente-Montilla, C., Crespo‐Facorro, B., & García-Cerro, S. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106032 · Cited by 12 · see citing works
Neurochemical Phenotype of Reelin Immunoreactive Cells in the Piriform Cortex Layer II
Carceller, H., Rovira-Esteban, L., Nácher, J., Ċastrén, E., & Guirado, R. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00065 · Cited by 12 · see citing works
ADAMTS2: More than a procollagen N-proteinase
Vanlerberghe, R., Colige, A., Malfait, A., Syx, D., & Malfait, F. (2025) · Genes & Diseases · doi:10.1016/j.gendis.2025.101686 · Cited by 11 · see citing works
Regulation of the hippocampal translatome by Apoer2-ICD release
Wasser, C. R., Werthmann, G. C., Hall, E. M., Kuhbandner, K., Wong, C. H. Y., Durakoglugil, M. S., & Herz, J. (2023) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00652-1 · Cited by 11 · see citing works
Self-citationReducing ADAMTS-3 Inhibits Amyloid β Deposition in App Knock-in Mouse
Yamakage, Y., Tsuiji, H., Kohno, T., Ogino, H., Saito, T., Saido, T. C., & Hattori, M. (2019) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b18-00899 · Cited by 11 · see citing works
Regulatory mechanism of Reelin activity: a platform for exploiting Reelin as a therapeutic agent
Hattori, M. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1546083 · Cited by 10 · see citing works
López‐Font, I., Lennol, M. P., Iborra‐Lázaro, G., Zetterberg, H., Blennow, K., & Sáez‐Valero, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147522 · Cited by 10 · see citing works
REELIN ameliorates Alzheimer's disease, but how?
Katsuyama, Y., & Hattori, M. (2024) · Neuroscience Research · doi:10.1016/j.neures.2024.07.004 · Cited by 9 · see citing works
Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila
Catterson, J. H., Minkley, L. J., Aspe, S., Judd-Mole, S., Moura, S., Dyson, M. C., Rajasingam, A., Woodling, N. S., Atilano, M. L., Ahmad, M., et al. (2023) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2023.09.008 · Cited by 9 · see citing works
Physiologic Reelin does not play a strong role in protection against acute stroke
Lane‐Donovan, C., DeSai, C., Pohlkamp, T., Plautz, E. J., Herz, J., & Stowe, A. M. (2016) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x16646386 · Cited by 8 · see citing works
Self-citationVisualization of Reelin Secretion from Primary Cultured Neurons by Bioluminescence Imaging
Nakao, Y., Yokawa, S., Kohno, T., Suzuki, T., & Hattori, M. (2022) · The Journal of Biochemistry · doi:10.1093/jb/mvac019 · Cited by 8 · see citing works
Loss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunction
Vandal, M., Institóris, Á., Réveret, L., Korin, B., Gunn, C., Hirai, S., Jiang, Y., Lee, S., Lee, J. Y., Bourassa, P., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.01.006 · Cited by 7 · see citing works
Reelin deficiency leads to aberrant lipid composition in mouse brain
Mizukami, T., Ikeda, K., Shimanaka, Y., Korogi, K., Zhou, C., Takase, H., Tsuiji, H., Kono, N., Kohno, T., Arai, H., et al. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.09.089 · Cited by 7 · see citing works
Hafner, G., Guy, J., Witte, M., Truschow, P., Rüppel, A., Sirmpilatze, N., Dadarwal, R., Boretius, S., & Staiger, J. F. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa280 · Cited by 7 · see citing works
Wu, M., He, Y., Zhang, J., Yang, J., & Qi, J. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.03.043 · Cited by 6 · see citing works
Two Novel Loci of RELN Associated With Antipsychotics Response in Chinese Han Population
Xu, Q., Li, M., Qin, S., Li, Y., Ning, A., Fu, Y., Wang, D., Zeng, D., Li, H., Yu, W., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00007 · Cited by 6 · see citing works
OCRL1 Deficiency Affects the Intracellular Traffic of ApoER2 and Impairs Reelin-Induced Responses
Fuentealba, L. M., Pizarro, H., & Marzolo, M. (2024) · Biomolecules · doi:10.3390/biom14070799 · Cited by 5 · see citing works
Brida, K. L., Jorgensen, E. T., Phillips, R. A., Newman, C. E., Tuscher, J. J., Morring, E. K., Zipperly, M. E., Ianov, L., Montgomery, K. D., Tippani, M., et al. (2025) · Science Advances · doi:10.1126/sciadv.ads4441 · Cited by 6 · see citing works
Normal connectivity of thalamorecipient networks in barrel equivalents of the reeler cortex
Meeuwissen, A., Möck, M., Staiger, J. F., & Guy, J. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad072 · Cited by 4 · see citing works
Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases
Calvier, L., Alexander, A., Marckx, A. T., Kounnas, M. Z., Durakoglugil, M. S., & Herz, J. (2024) · Cells · doi:10.3390/cells13070583 · Cited by 6 · see citing works
Self-citationBiolistic transfection and expression analysis of acute cortical slices
Hamad, M. I. K., Daoud, S., Petrova, P., Rabaya, O., Jbara, A., Melliti, N., Stichmann, S., Reiss, G., Herz, J., & Förster, E. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.108666 · Cited by 4 · see citing works
Self-citationGenetic variants beyond amyloid and tau associated with cognitive decline
Kim, H., Lee, T., Choi, J. K., Jeong, Y., Weiner, M. W., Aisen, P., Weiner, M. W., Aisen, P. S. S., Petersen, R. C., Jack, C. R., et al. (2020) · Neurology · doi:10.1212/wnl.0000000000010724 · Cited by 4 · see citing works
Reelin Regulates Developmental Desynchronization Transition of Neocortical Network Activity
Hamad, M. I. K., Rabaya, O., Jbara, A., Daoud, S., Petrova, P., Ali, B. R., Allouh, M. Z., Herz, J., & Förster, E. (2024) · Biomolecules · doi:10.3390/biom14050593 · Cited by 3 · see citing works
Self-citationEpilepsy-Associated Reelin Dysfunction Induces Granule Cell Dispersion in the Dentate Gyrus☆
Frotscher, M., & Haas, C. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.00032-8 · Cited by 3 · see citing works
Self-citationMata, Á., Urrea, L., Vilches, S., Llorens, F., Thüne, K., Espinosa, J. C., Andréoletti, O., Sevillano, A. M., Torres, J. M., Requena, J. R., et al. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0177-8 · Cited by 3 · see citing works
Idolizing the clearance of Amyloid-β by microglia
van Loon, N. M., & Zelcer, N. (2016) · Annals of Translational Medicine · doi:10.21037/atm.2016.11.63 · Cited by 3 · see citing works
NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque loadPreprint
Pohlkamp, T., Xian, X., Wong, C. H. Y., Durakoglugil, M. S., Werthmann, G. C., Saido, T., Evers, B. M., White, C. L., Connor, J., Hammer, R., et al. (2021) · bioRxiv · doi:10.1101/2021.03.22.436385 · Cited by 40 · see citing works
Self-citationThe Alzheimer risk factor CD2AP causes dysfunction of the brain vascular networkPreprint
Vandal, M., Institóris, Á., Korin, B., Gunn, C., Lee, S., Lee, J. Y., Bourassa, P., Mishra, R. C., Peringod, G., Jiang, Y., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.10.419598 · Cited by 2 · see citing works
Brida, K. L., Jorgensen, E. T., Phillips, R. A., Newman, C. E., Tuscher, J. J., Morring, E. K., Zipperly, M. E., Ianov, L., Montgomery, K. D., Tippani, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.17.599348 · Cited by 2 · see citing works
Mirkamali, A., & Jahromi, S. R. (2025) · Russian Journal of Genetics · doi:10.1134/s1022795425700425 · Cited by 1 · see citing works
Durakoglugil, M. S. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1731914 · Cited by 1 · see citing works
Self-citationSaravanan, J., Easwaran, V., Selvaraj, D., Gunasekaran, V., Soumya, V., Thiruselvi, M., Prasanth, M. L., Singh, S., Ellaiyarasu, C., Rai, P. K., et al. (2026) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2026.104108 · Cited by 1 · see citing works
Liu, Y., Liang, R., Zhu, D., Wang, Q., Li, Z., Cheng, L., Ren, J., Guo, Y., Chai, H., Wang, M., et al. (2023) · Toxicology and Industrial Health · doi:10.1177/07482337221150859 · Cited by 1 · see citing works
Leveraging signaling research to understand and treat disease
Yaffe, M. B., & Gough, N. R. (2016) · Science Signaling · doi:10.1126/scisignal.aaf6275 · Cited by 1 · see citing works
Bray, N. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn4006
Science Signaling Podcast: 7 July 2015
Lane‐Donovan, C., Herz, J., & VanHook, A. M. (2015) · Science Signaling · doi:10.1126/scisignal.aac8470
Self-citationResearch progress of platelets in neurodegenerative diseases
Yu, L., Ding, J., Yu, T., & Cheng, C. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1544605 · Cited by 1 · see citing works
- Authors
- Lane-Donovan, C., Philips, G. T., Wasser, C. R., Durakoglugil, M. S., Masiulis, I., Upadhaya, A., Pohlkamp, T., Coskun, C., Kotti, T., Steller, L., Hammer, R. E., Frotscher, M., Bock, H. H., & Herz, J.
- Affiliations
- Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
- New York University (US)
- The University of Texas Southwestern Medical Center (US)
- University of Freiburg (DE)
- Institute for Structural Neurobiology, Center for Molecular Neurobiology, Hamburg 20251, Germany.
- Heinrich Heine University Düsseldorf (DE)
- Corresponding author
- Herz, Joachim
- ORCID
- Venue
- Science Signaling
- Published
- 2015-07-07
- Volume
- 8
- Issue
- 384
- Pages
- ra67-ra67
- ISSN
- 1937-9145 (ISSN-L)
- 1945-0877
- PMC
- PMC4652952
- OpenAlex
- W1904116405
- Cited by
- 96
- References
- 73
- Citations by year
- 2026: 1 · 2025: 10 · 2024: 8 · 2023: 6 · 2022: 4 · 2021: 9 · 2020: 14 · 2019: 6 · 2018: 5 · 2017: 8 · 2016: 23 · 2015: 2
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Signaling (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- FreiDok plus (Universitätsbibliothek Freiburg) (submittedVersion)
- Funders
- NIH (F30 AG047799, R37 HL63762)
- American Health Assistance Foundation
- Consortium for Frontotemporal Dementia Research
- Bright Focus Foundation
- Lupe Murchison Foundation
- The Ted Nash Long Life Foundation
- Deutsche Forschungsgemeinschaft (FR 620/12-1, SFB 780/TP5)
- Bundesministerium fur Bildung und Forschung
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- reelin, amyloid-beta, Alzheimer's disease, APOE ε4, ApoER2, VLDLR, synaptic plasticity, synaptic dysfunction, memory impairment, learning deficits, receptor recycling, neuroprotection
- MeSH terms
- Reelin Protein, Alzheimer Disease, Animals, Brain, Humans, Immunohistochemistry, Memory Disorders, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Nerve Tissue Proteins, Receptors, LDL, Serine Endopeptidases, Blotting, Western, Cell Adhesion Molecules, Neuronal, Amyloid beta-Peptides, Extracellular Matrix Proteins, Long-Term Potentiation, Mice, Knockout, Maze Learning, LDL-Receptor Related Proteins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
