Kanaar, Roland

Chromosomal stability and the DNA double-stranded break connection

van Gent, D. C., Hoeijmakers, J. H. J., & Kanaar, R. (2001) · Nature Reviews Genetics

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,219

Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends

de Jager, M., van Noort, J., van Gent, D. C., Dekker, C., Kanaar, R., & Wyman, C. (2001) · Molecular Cell

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 512

Dynamics of DNA Double-Strand Breaks Revealed by Clustering of Damaged Chromosome Domains

Aten, J. A., Stap, J., Krawczyk, P. M., van Oven, C. H., Hoebe, R. A., Essers, J., & Kanaar, R. (2004) · Science

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 491

Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia

Zambetti, N. A., Ping, Z., Chen, S., Kenswil, K. J. G., Mylona, M. A., Sanders, M. A., Hoogenboezem, R. M., Bindels, E. M. J., Adisty, M. N., Van Strien, P. M. H., et al. (2016) · Cell stem cell

Blood disorders and treatmentsHematopoietic Stem Cell Transplantation

Cited by 342

A microfluidic cancer-on-chip platform predicts drug response using organotypic tumor slice culture

Chakrabarty, S., Quiros-Solano, W. F., Kuijten, M. M. P., Haspels, B., Mallya, S., Lo, C. S. Y., Othman, A., Silvestri, C., van de Stolpe, A., Gaio, N., et al. (2022) · Cancer Research

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 61

Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress

Warmerdam, D. O., Freire, R., Kanaar, R., & Smits, V. A. J. (2009) · Cell Cycle

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 28

DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces

Miron, S., Legrand, P., van Rossum-Fikkert, S. E., Ristic, D., Badar, A., Kanaar, R., Zinn-Justin, S., & Zelensky, A. N. (2023) · Nucleic Acids Research

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 12

BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination

Ghouil, R., Miron, S., Sato, K., Ristic, D., van Rossum-Fikkert, S. E., Legrand, P., Ouldali, M., Winter, J.-M., Ropars, V., David, G., et al. (2023) · Science Advances

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 2