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Brca1 Controls Homology-Directed DNA Repair

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The importance of repairing stalled replication forks

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The DNA-dependent protein kinasePreprint

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A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

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Sister chromatid gene conversion is a prominent double‐strand break repair pathway in mammalian cells

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The Breast Cancer Susceptibility Gene BRCA1 Is Required for Subnuclear Assembly of Rad51 and Survival following Treatment with the DNA Cross-linking Agent Cisplatin

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Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes.

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DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.Preprint

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Frequent chromosomal translocations induced by DNA double-strand breaks

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

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DNA Ligase IV Deficiency in Mice Leads to Defective Neurogenesis and Embryonic Lethality via the p53 Pathway

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Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

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ATM-dependent phosphorylation of nibrin in response to radiation exposure

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Growth Retardation and Leaky SCID Phenotype of Ku70-Deficient Mice

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Proteomics: new perspectives, new biomedical opportunities

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Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

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Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination

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A Targeted DNA-PKcs-Null Mutation Reveals DNA-PK-Independent Functions for KU in V(D)J Recombination

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Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

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The Many Interfaces of Mre11

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Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

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Deletion of Ku86 causes early onset of senescence in mice

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Single-molecule analysis of DNA uncoiling by a type II topoisomerase

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Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.

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Ku acts in a unique way at the mammalian telomere to prevent end joiningPreprint

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Insights into the functions of BRCA1 and BRCA2

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Targeted Inactivation of Mouse RAD52Reduces Homologous Recombination but Not Resistance to Ionizing Radiation

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Targeted Disruption of the Catalytic Subunit of the DNA-PK Gene in Mice Confers Severe Combined Immunodeficiency and Radiosensitivity

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Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

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ATM: from gene to function

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Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification

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Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivationPreprint

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Ku complex interacts with and stimulates the Werner proteinPreprint

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Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang

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Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

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The controlling role of ATM in homologous recombinational repair of DNA damage

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Mass spectrometry and proteomics

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Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

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The Rad51 Paralog Rad51B Promotes Homologous Recombinational Repair

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Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo

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Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

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Xrcc3 Is Required for Assembly of Rad51 Complexes in Vivo

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ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks

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Cancer Susceptibility and the Functions of BRCA1 and BRCA2

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Genomic Instability in Mice Lacking Histone H2AX

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

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Targeted Chromosomal Cleavage and Mutagenesis in Drosophila Using Zinc-Finger Nucleases

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Chromosome aberrations in solid tumors

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DNA damage responses to oxidative stress

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Aging and Genome Maintenance: Lessons from the Mouse?

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The endless tale of non-homologous end-joining

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γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes

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A Double-Strand Break Repair Defect in ATM-Deficient Cells Contributes to Radiosensitivity

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Chk2 Phosphorylation of BRCA1 Regulates DNA Double-Strand Break Repair

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Chromosome breakage after G2 checkpoint release

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Early neuronal accumulation of DNA double strand breaks in Alzheimer’s disease

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HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair

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Hsp90: A New Player in DNA Repair?

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An Imperfect G ₂ M Checkpoint Contributes to Chromosome Instability Following Irradiation of S and G ₂ Phase Cells

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DNA double-strand breaks: Their production, recognition, and repair in eukaryotes

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Arabidopsis mutants sensitive to gamma radiation include the homologue of the human repair gene ERCC1

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Evolutionary and Functional Conservation of the DNA Non-homologous End-joining Protein, XLF/Cernunnos

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Escape from Telomere-Driven Crisis Is DNA Ligase III Dependent

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An LTR retrotransposon‐derived lncRNA interacts with RNF169 to promote homologous recombination

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Disordered regions mediate the interaction of p53 and MRE11

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Genomic Instability in CancerPreprint

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The presence of extra chromosomes leads to genomic instability

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Radiation-induced genomic instability and its implications for radiation carcinogenesis

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Multiple Regulatory Mechanisms to Inhibit Untimely Initiation of DNA Replication Are Important for Stable Genome Maintenance

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