Ward, Diane McVey

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., & Kaplan, J. (2004) · Science

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 4,803

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

Alexander, M., Hu, R., Runtsch, M. C., Kagele, D. A., Mosbruger, T. L., Tolmachova, T., Seabra, M. C., Round, J. L., Ward, D. M., & O’Connell, R. M. (2015) · Nature Communications

Extracellular vesicles in diseaseMicroRNA in disease regulation

Cited by 769

The Molecular Mechanism of Hepcidin-mediated Ferroportin Down-Regulation

De Domenico, I., Ward, D. M., Langelier, C., Vaughn, M. B., Nemeth, E., Sundquist, W. I., Ganz, T., Musci, G., & Kaplan, J. (2007) · Molecular Biology of the Cell

Iron Metabolism and DisordersCellular transport and secretion

Cited by 434

Ferroportin-mediated iron transport: Expression and regulation

Ward, D. M., & Kaplan, J. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 373

CCC1 Is a Transporter That Mediates Vacuolar Iron Storage in Yeast

Li, L., Chen, O. S., Ward, D. M., & Kaplan, J. (2001) · Journal of Biological Chemistry

Iron Metabolism and DisordersFungal and yeast genetics research

Cited by 354

Ferroportin‐mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

De Domenico, I., Vaughn, M. B., Li, L., Bagley, D., Musci, G., Ward, D. M., & Kaplan, J. (2006) · The EMBO Journal

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 235

Iron depletion limits intracellular bacterial growth in macrophages

Paradkar, P. N., De Domenico, I., Durchfort, N., Zohn, I., Kaplan, J., & Ward, D. M. (2008) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 216

Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice

De Domenico, I., Zhang, T. Y., Koening, C. L., Branch, R. W., London, N., Lo, E., Daynes, R. A., Kushner, J. P., Li, D., Ward, D. M., et al. (2010) · Journal of Clinical Investigation

Iron Metabolism and DisordersCytokine Signaling Pathways and Interactions

Cited by 197

Specific iron chelators determine the route of ferritin degradation

De Domenico, I., Ward, D. M., & Kaplan, J. (2009) · Blood

Iron Metabolism and DisordersAutophagy in Disease and Therapy

Cited by 176

Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release

Langelier, C., von Schwedler, U. K., Fisher, R. D., De Domenico, I., White, P. L., Hill, C. P., Kaplan, J., Ward, D., & Sundquist, W. I. (2006) · Journal of Virology

Cellular transport and secretionHIV Research and Treatment

Cited by 166

Yap5 Is an Iron-Responsive Transcriptional Activator That Regulates Vacuolar Iron Storage in Yeast

Li, L., Bagley, D., Ward, D. M., & Kaplan, J. (2008) · Molecular and Cellular Biology

Fungal and yeast genetics researchIron Metabolism and Disorders

Cited by 121

The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease.

Zohn, I. E., De Domenico, I., Pollock, A., Ward, D. M., Goodman, J. F., Liang, X., Sanchez, A. J., Niswander, L., & Kaplan, J. (2007) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 104

Leishmania-Mediated Inhibition of Iron Export Promotes Parasite Replication in Macrophages

Ben-Othman, R., Flannery, A. R., Miguel, D. C., Ward, D. M., Kaplan, J., & Andrews, N. W. (2014) · PLoS Pathogens

Research on Leishmaniasis StudiesIron Metabolism and Disorders

Cited by 76

Evidence for the multimeric structure of ferroportin.

De Domenico, I., Ward, D. M., Musci, G., & Kaplan, J. (2007) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 72

Identification of a Candida albicans Ferrichrome Transporter and Its Characterization by Expression inSaccharomyces cerevisiae

Ardon, O., Bussey, H., Philpott, C., Ward, D. M., Davis-Kaplan, S., Verroneau, S., Jiang, B., & Kaplan, J. (2001) · Journal of Biological Chemistry

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 68

Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25

Runkel, F., Büssow, H., Seburn, K. L., Cox, G. A., Ward, D. M., Kaplan, J., & Franz, T. (2006) · Mammalian Genome

melanin and skin pigmentationImmunodeficiency and Autoimmune Disorders

Cited by 61

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

Chung, J., Anderson, S. A., Gwynn, B., Deck, K. M., Chen, M. J., Langer, N. B., Shaw, G. C., Huston, N. C., Boyer, L. F., Datta, S., et al. (2014) · Journal of Biological Chemistry

Porphyrin Metabolism and DisordersIron Metabolism and Disorders

Cited by 39

Altered sterol metabolism in budding yeast affects mitochondrial iron-sulfur (Fe-S) cluster synthesis

Ward, D. M., Chen, O. S., Li, L., Kaplan, J., Bhuiyan, S. A., Natarajan, S. K., Bard, M., & Cox, J. E. (2018) · Journal of Biological Chemistry

Mitochondrial Function and PathologyFungal and yeast genetics research

Cited by 32