Wanders, Ronald J.A.

A general introduction to the biochemistry of mitochondrial fatty acid β‐oxidation

Houten, S. M., & Wanders, R. J. A. (2010) · Journal of Inherited Metabolic Disease

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 1,020

Biochemistry of mammalian peroxisomes revisited

Wanders, R. J. A., & Waterham, H. R. (2006) · Annual Review of Biochemistry

Metabolism and Genetic DisordersPeroxisome Proliferator-Activated Receptors

Cited by 995

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

Houtkooper, R. H., Cantó, C., Wanders, R. J., & Auwerx, J. (2010) · Endocrine Reviews

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 899

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

Wang, G., McCain, M. L., Yang, L., He, A., Pasqualini, F. S., Agarwal, A., Yuan, H., Jiang, D., Zhang, D., Zangi, L., et al. (2014) · Nature Medicine

Pluripotent Stem Cells ResearchMitochondrial Function and Pathology

Cited by 837

A Lethal Defect of Mitochondrial and Peroxisomal Fission

Waterham, H. R., Koster, J., van Roermund, C. W. T., Mooyer, P. A. W., Wanders, R. J. A., & Leonard, J. V. (2007) · New England Journal of Medicine

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 749

X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management

Engelen, M., Kemp, S., de Visser, M., van Geel, B. M., Wanders, R. J., Aubourg, P., & Poll-The, B. (2012) · Orphanet Journal of Rare Diseases

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 562

Metabolic Interplay between Peroxisomes and Other Subcellular Organelles Including Mitochondria and the Endoplasmic Reticulum

Wanders, R. J. A., Waterham, H. R., & Ferdinandusse, S. (2016) · Frontiers in Cell and Developmental Biology

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 366

The ABC transporter proteins Pat1 and Pat2 are required for import of long‐chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

Hettema, E. H., van Roermund, C. W., Distel, B., van den Berg, M., Vilela, C., Rodrigues‐Pousada, C., Wanders, R. J., & Tabak, H. F. (1996) · The EMBO Journal

Lipid metabolism and biosynthesisMetabolism and Genetic Disorders

Cited by 323

ABCD1 mutations and the X-linked adrenoleukodystrophy mutation database: Role in diagnosis and clinical correlations

Kemp, S., Pujol, A., Waterham, H. R., van Geel, B. M., Boehm, C. D., Raymond, G. V., Cutting, G. R., Wanders, R. J. A., & Moser, H. W. (2001) · Human Mutation

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 321

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

Shai, N., Yifrach, E., van Roermund, C. W. T., Cohen, N., Bibi, C., IJlst, L., Cavellini, L., Meurisse, J., Schuster, R., Zada, L., et al. (2018) · Nature Communications

Mitochondrial Function and PathologyCellular transport and secretion

Cited by 320

Smith-Lemli-Opitz Syndrome Is Caused by Mutations in the 7-Dehydrocholesterol Reductase Gene

Waterham, H. R., Wijburg, F. A., Hennekam, R. C. M., Vreken, P., Poll-The, B. T., Dorland, L., Duran, M., Jira, P. E., Smeitink, J. A. M., Wevers, R. A., et al. (1998) · The American Journal of Human Genetics

Metabolism and Genetic DisordersCholesterol and Lipid Metabolism

Cited by 296

Adrenoleukodystrophy—Neuroendocrine pathogenesis and redefinition of natural history

Kemp, S., Huffnagel, I. C., Linthorst, G. E., Wanders, R. J., & Engelen, M. (2016) · Nature Reviews Endocrinology

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 275

Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy

Ferdinandusse, S., Denis, S., Clayton, P. T., Graham, A., Rees, J. E., Allen, J. T., McLean, B. N., Brown, A. Y., Vreken, P., Waterham, H. R., et al. (2000) · Nature Genetics

Hereditary Neurological DisordersMetabolism and Genetic Disorders

Cited by 262

Disorders of mitochondrial fatty acyl‐CoA β‐oxidation

Wanders, R. J. A., Vreken, P., den Boer, M. E. J., Wijburg, F. A., Van Gennip, A. H., & IJlst, L. (1999) · Journal of Inherited Metabolic Disease

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 257

X-linked adrenoleukodystrophy in women: A cross-sectional cohort study

Engelen, M., Barbier, M., Dijkstra, I. M. E., Schür, R., de Bie, R. M. A., Verhamme, C., Dijkgraaf, M. G. W., Aubourg, P. A., Wanders, R. J. A., van Geel, B. M., et al. (2014) · Brain

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 234

The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl–CoA esters

van Roermund, C. W. T., Visser, W. F., IJlst, L., van Cruchten, A., Boek, M., Kulik, W., Waterham, H. R., & Wanders, R. J. A. (2008) · The FASEB Journal

Metabolism and Genetic DisordersDrug Transport and Resistance Mechanisms

Cited by 233

Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling

Wiese, S., Gronemeyer, T., Ofman, R., Kunze, M., Grou, C. P., Almeida, J. A., Eisenacher, M., Stephan, C., Hayen, H., Schollenberger, L., et al. (2007) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsRedox biology and oxidative stress

Cited by 231

The physiological functions of human peroxisomes

Wanders, R. J. A., Baes, M., Ribeiro, D., Ferdinandusse, S., & Waterham, H. R. (2023) · Physiological Reviews

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 228

Peroxisomal alterations in Alzheimer’s disease

Kou, J., Kovacs, G. G., Höftberger, R., Kulik, W., Brodde, A., Forss-Petter, S., Hönigschnabl, S., Gleiss, A., Brügger, B., Wanders, R., et al. (2011) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 227

Peroxisomal fatty acid α- and β -oxidation in humans: enzymology, peroxisomal metabolite transporters and peroxisomal diseases

Wanders, R. J. A., Vreken, P., Ferdinandusse, S., Jansen, G. A., Waterham, H. R., van Roermund, C. W. T., & Van Grunsven, E. G. (2001) · Biochemical Society Transactions

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 225

The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy

Ofman, R., Dijkstra, I. M. E., van Roermund, C. W. T., Burger, N., Turkenburg, M., van Cruchten, A., van Engen, C. E., Wanders, R. J. A., & Kemp, S. (2010) · EMBO Molecular Medicine

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 170

Peroxisomes, lipid metabolism and lipotoxicity

Wanders, R. J. A., Ferdinandusse, S., Brites, P., & Kemp, S. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 169

X linked adrenoleukodystrophy: clinical presentation, diagnosis, and therapy

van Geel, B. M., Assies, J., Wanders, R. J. A., & Barth, P. G. (1997) · Journal of Neurology, Neurosurgery & Psychiatry

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 162

Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids

De Marcos Lousa, C., van Roermund, C. W. T., Postis, V. L. G., Dietrich, D., Kerr, I. D., Wanders, R. J. A., Baldwin, S. A., Baker, A., & Theodoulou, F. L. (2013) · Proceedings of the National Academy of Sciences

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 158