Laganowsky, Arthur

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

Zhao, B., Du, F., Xu, P., Shu, C., Sankaran, B., Bell, S. L., Liu, M., Lei, Y., Gao, X., Fu, X., et al. (2019) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 447

Mass spectrometry of intact membrane protein complexes

Laganowsky, A., Reading, E., Hopper, J. T. S., & Robinson, C. V. (2013) · Nature Protocols

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 409

The Role of the Detergent Micelle in Preserving the Structure of Membrane Proteins in the Gas Phase

Reading, E., Liko, I., Allison, T. M., Benesch, J. L. P., Laganowsky, A., & Robinson, C. V. (2015) · Angewandte Chemie International Edition

Mass Spectrometry Techniques and ApplicationsLipid Membrane Structure and Behavior

Cited by 137

A hydrophobic ratchet entrenches molecular complexes

Hochberg, G. K. A., Liu, Y., Marklund, E. G., Metzger, B. P. H., Laganowsky, A., & Thornton, J. W. (2020) · Nature

Evolution and Genetic DynamicsProtein Structure and Dynamics

Cited by 134

Structure and mechanism of human diacylglycerol O-acyltransferase 1

Wang, L., Qian, H., Nian, Y., Han, Y., Ren, Z., Zhang, H., Hu, L., Prasad, B. V. V., Laganowsky, A., Yan, N., et al. (2020) · Nature

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 123

Structural basis of ion transport and inhibition in ferroportin

Pan, Y., Ren, Z., Gao, S., Shen, J., Wang, L., Xu, Z., Yu, Y., Bachina, P., Zhang, H., Fan, X., et al. (2020) · Nature Communications

Iron Metabolism and DisordersProtein Structure and Dynamics

Cited by 81

Enhanced Characterization of Membrane Protein Complexes by Ultraviolet Photodissociation Mass Spectrometry

Sipe, S. N., Patrick, J. W., Laganowsky, A., & Brodbelt, J. S. (2020) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 39

Intrinsic GTPase activity of K-RAS monitored by native mass spectrometry

Moghadamchargari, Z., Huddleston, J., Shirzadeh, M., Zheng, X., Clemmer, D. E., M. Raushel, F., Russell, D. H., & Laganowsky, A. (2019) · Biochemistry

Protein Kinase Regulation and GTPase SignalingMass Spectrometry Techniques and Applications

Cited by 38

Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants

Moghadamchargari, Z., Shirzadeh, M., Liu, C., Schrecke, S., Packianathan, C., Russell, D. H., Zhao, M., & Laganowsky, A. (2021) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 38

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

Tetreau, G., Sawaya, M. R., De Zitter, E., Andreeva, E. A., Banneville, A.-S., Schibrowsky, N. A., Coquelle, N., Brewster, A. S., Grünbein, M. L., Kovacs, G. N., et al. (2022) · Nature Communications

Enzyme Structure and FunctionInsect Resistance and Genetics

Cited by 28

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

Tetreau, G., Sawaya, M. R., De Zitter, E., Andreeva, E. A., Banneville, A.-S., Schibrowsky, N., Coquelle, N., Brewster, A. S., Grünbein, M. L., Kovacs, G. N., et al. (2021) · Nature Communications

Enzyme Structure and FunctionInsect Resistance and Genetics

Cited by 28

Design of a symmetry-broken tetrahedral protein cage by a method of internal steric occlusion

Gladkov, N., Scott, E. A., Meador, K., Lee, E. J., Laganowsky, A. D., Yeates, T. O., & Castells-Graells, R. (2023) · Protein Science

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 8