Akl, Elie A.

Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 1 of 3. An overview of the GRADE approach and grading quality of evidence about interventions

Brożek, J. L., Akl, E. A., Alonso‐Coello, P., Lang, D., Jaeschke, R., Williams, J. W., Phillips, B., Lelgemann, M., Lethaby, A., Bousquet, J., et al. (2009) · Allergy

Clinical practice guidelines implementationMeta-analysis and systematic reviews

Cited by 894

The GRADE Working Group clarifies the construct of certainty of evidence

Hultcrantz, M., Rind, D., Akl, E. A., Treweek, S., Mustafa, R. A., Iorio, A., Alper, B. S., Meerpohl, J. J., Murad, M. H., Ansari, M. T., et al. (2017) · Journal of Clinical Epidemiology

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 853

GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines

Alonso-Coello, P., Oxman, A. D., Moberg, J., Brignardello-Petersen, R., Akl, E. A., Davoli, M., Treweek, S., Mustafa, R. A., Vandvik, P. O., Meerpohl, J., et al. (2016) · BMJ

Clinical practice guidelines implementationHealth Sciences Research and Education

Cited by 814

GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles—continuous outcomes

Guyatt, G. H., Thorlund, K., Oxman, A. D., Walter, S. D., Patrick, D., Furukawa, T. A., Johnston, B. C., Karanicolas, P., Akl, E. A., Vist, G., et al. (2013) · Journal of Clinical Epidemiology

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 772

GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes

Guyatt, G., Oxman, A. D., Sultan, S., Brozek, J., Glasziou, P., Alonso-Coello, P., Atkins, D., Kunz, R., Montori, V., Jaeschke, R., et al. (2013) · Journal of Clinical Epidemiology

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 762

Guideline for opioid therapy and chronic noncancer pain

Busse, J. W., Craigie, S., Juurlink, D. N., Buckley, D. N., Wang, L., Couban, R. J., Agoritsas, T., Akl, E. A., Carrasco-Labra, A., Cooper, L., et al. (2017) · Canadian Medical Association Journal

Opioid Use Disorder TreatmentPain Management and Opioid Use

Cited by 707

Guidelines 2.0: Systematic development of a comprehensive checklist for a successful guideline enterprise

Schünemann, H. J., Wiercioch, W., Etxeandia, I., Falavigna, M., Santesso, N., Mustafa, R., Ventresca, M., Brignardello-Petersen, R., Laisaar, K.-T., Kowalski, S., et al. (2014) · Canadian Medical Association Journal

Clinical practice guidelines implementationHealth Sciences Research and Education

Cited by 686

Completing ‘Summary of findings’ tables and grading the certainty of the evidence

Schünemann, H. J., Higgins, J. P., Vist, G. E., Glasziou, P., Akl, E. A., Skoetz, N., Guyatt, G. H., & on behalf of the Cochrane GRADEing Methods Group (formerly Applicability and Recommendations Methods Group) and the Cochrane Statistical Methods Group (2019) · Cochrane Handbook for Systematic Reviews of Interventions

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 669

The effects of waterpipe tobacco smoking on health outcomes: a systematic review

Akl, E. A., Gaddam, S., Gunukula, S. K., Honeine, R., Jaoude, P. A., & Irani, J. (2010) · International Journal of Epidemiology

Smoking Behavior and CessationChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 624

Primary and Secondary Prevention of Cardiovascular Disease

Vandvik, P. O., Lincoff, A. M., Gore, J. M., Gutterman, D. D., Sonnenberg, F. A., Alonso-Coello, P., Akl, E. A., Lansberg, M. G., Guyatt, G. H., & Spencer, F. A. (2012) · Chest

Antiplatelet Therapy and Cardiovascular DiseasesCoronary Interventions and Diagnostics

Cited by 476

Randomisation to protect against selection bias in healthcare trials

Odgaard-Jensen, J., Vist, G. E., Timmer, A., Kunz, R., Akl, E. A., Schünemann, H., Briel, M., Nordmann, A. J., Pregno, S., & Oxman, A. D. (2011) · Cochrane Database of Systematic Reviews

Meta-analysis and systematic reviewsStatistical Methods in Clinical Trials

Cited by 439

When and how to update systematic reviews: consensus and checklist

Garner, P., Hopewell, S., Chandler, J., MacLehose, H., Schünemann, H. J., Akl, E. A., Beyene, J., Chang, S., Churchill, R., Dearness, K., et al. (2016) · BMJ

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 426

The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses

Mustafa, R. A., Santesso, N., Brozek, J., Akl, E. A., Walter, S. D., Norman, G., Kulasegaram, M., Christensen, R., Guyatt, G. H., Falck-Ytter, Y., et al. (2013) · Journal of Clinical Epidemiology

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 370

Living systematic reviews: 2. Combining human and machine effort

Thomas, J., Noel-Storr, A., Marshall, I., Wallace, B., McDonald, S., Mavergames, C., Glasziou, P., Shemilt, I., Synnot, A., Turner, T., et al. (2017) · Journal of Clinical Epidemiology

Meta-analysis and systematic reviewsAcademic Publishing and Open Access

Cited by 355

Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review

Akl, E. A., Briel, M., You, J. J., Sun, X., Johnston, B. C., Busse, J. W., Mulla, S., Lamontagne, F., Bassler, D., Vera, C., et al. (2012) · BMJ

Statistical Methods in Clinical TrialsMeta-analysis and systematic reviews

Cited by 350

Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170,255 patients from 76 randomized trials

Mills, E. J., WU, P., Chong, G., Ghement, I., Singh, S., Akl, E. A., Eyawo, O., Guyatt, G., Berwanger, O., & Briel, M. (2011) · QJM

Lipoproteins and Cardiovascular HealthCancer, Lipids, and Metabolism

Cited by 338

Effects of higher- versus lower-protein diets on health outcomes: a systematic review and meta-analysis.

Santesso, N., Akl, E. A., Bianchi, M., Mente, A., Mustafa, R., Heels-Ansdell, D., & Schünemann, H. J. (2012) · European Journal of Clinical Nutrition

Diet and metabolism studiesMuscle metabolism and nutrition

Cited by 292

GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach

Zeng, L., Brignardello-Petersen, R., Hultcrantz, M., Mustafa, R. A., Murad, M. H., Iorio, A., Traversy, G., Akl, E. A., Mayer, M., Schünemann, H. J., et al. (2022) · Journal of Clinical Epidemiology

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 285

Assessing and presenting summaries of evidence in Cochrane Reviews

Langendam, M. W., Akl, E. A., Dahm, P., Glasziou, P., Guyatt, G., & Schünemann, H. J. (2013) · Systematic Reviews

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 282

Grading quality of evidence and strength of recommendations in clinical practice guidelines: part 2 of 3. the GRADE approach to grading quality of evidence about diagnostic tests and strategies

Brożek, J. L., Akl, E. A., Jaeschke, R., Lang, D. M., Bossuyt, P., Glasziou, P., Helfand, M., Ueffing, E., Alonso‐Coello, P., Meerpohl, J., et al. (2009) · Allergy

Clinical practice guidelines implementationMeta-analysis and systematic reviews

Cited by 270

The GRADE approach and Bradford Hill's criteria for causation

Schünemann, H., Hill, S., Guyatt, G., Akl, E. A., & Ahmed, F. (2011) · Journal of Epidemiology and Community Health

Clinical practice guidelines implementationMeta-analysis and systematic reviews

Cited by 262

Using systematic reviews in guideline development: The GRADE approach

Zhang, Y., Akl, E. A., & Schünemann, H. J. (2019) · Research Synthesis Methods

Meta-analysis and systematic reviewsClinical practice guidelines implementation

Cited by 260

A risk of bias instrument for non-randomized studies of exposures: A users' guide to its application in the context of GRADE

Morgan, R. L., Thayer, K. A., Santesso, N., Holloway, A. C., Blain, R., Eftim, S. E., Goldstone, A. E., Ross, P., Ansari, M., Akl, E. A., et al. (2019) · Environment International

Meta-analysis and systematic reviewsStatistical Methods in Epidemiology

Cited by 248

Non‐randomized studies as a source of complementary, sequential or replacement evidence for randomized controlled trials in systematic reviews on the effects of interventions

Schünemann, H. J., Tugwell, P., Reeves, B. C., Akl, E. A., Santesso, N., Spencer, F. A., Shea, B., Wells, G., & Helfand, M. (2013) · Research Synthesis Methods

Meta-analysis and systematic reviewsAdvanced Causal Inference Techniques

Cited by 248