Olsen, Christian A.

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

Tan, M., Peng, C., Anderson, K. A., Chhoy, P., Xie, Z., Dai, L., Park, J., Chen, Y., Huang, H., Zhang, Y., et al. (2014) · Cell Metabolism

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SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion

Anderson, K. A., Huynh, F. K., Fisher-Wellman, K., Stuart, J. D., Peterson, B. S., Douros, J. D., Wagner, G. R., Thompson, J. W., Madsen, A. S., Green, M. F., et al. (2017) · Cell Metabolism

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Histone deacetylase 11 is an ε-N-Myristoyllysine hydrolase

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Profiling of Substrates for Zinc‐dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro

Madsen, A. S., & Olsen, C. A. (2012) · Angewandte Chemie International Edition

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Chiral Posttranslational Modification to Lysine ε-Amino Groups

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Innovative Strategies for Selective Inhibition of Histone Deacetylases

Maolanon, A. R., Madsen, A. S., & Olsen, C. A. (2016) · Cell Chemical Biology

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A continuous, fluorogenic sirtuin 2 deacylase assay: substrate screening and inhibitor evaluation

Galleano, I., Schiedel, M., Jung, M., Madsen, A. S., & Olsen, C. A. (2016) · Journal of Medicinal Chemistry

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Determination of Slow-binding HDAC Inhibitor Potency and Subclass Selectivity

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Chemical editing of macrocyclic natural products and kinetic profiling reveal slow, tight-binding histone deacetylase inhibitors with picomolar affinities

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Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

Moreno-Yruela, C., Fass, D. M., Cheng, C., Herz, J., Olsen, C. A., & Haggarty, S. J. (2019) · ACS Chemical Neuroscience

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Photo Cross‐Linking Probes Containing ϵ‐ N ‐Thioacyllysine and ϵ‐ N ‐Acyl‐(δ‐aza)lysine Residues

Bæk, M., Martín‐Gago, P., Laursen, J. S., Madsen, J. L. H., Chakladar, S., & Olsen, C. A. (2020) · Chemistry – A European Journal

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