Lawley, Trevor D.

A new genomic blueprint of the human gut microbiota

Almeida, A., Mitchell, A. L., Boland, M., Forster, S. C., Gloor, G. B., Tarkowska, A., Lawley, T. D., & Finn, R. D. (2019) · Nature

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 1,314

Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation

Browne, H. P., Forster, S. C., Anonye, B. O., Kumar, N., Neville, B. A., Stares, M. D., Goulding, D., & Lawley, T. D. (2016) · Nature

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1,299

Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth

Shao, Y., Forster, S. C., Tsaliki, E., Vervier, K., Strang, A., Simpson, N., Kumar, N., Stares, M. D., Rodger, A., Brocklehurst, P., et al. (2019) · Nature

Gut microbiota and healthInfant Nutrition and Health

Cited by 1,088

Intestinal colonization resistance

Lawley, T. D., & Walker, A. W. (2013) · Immunology

Gut microbiota and healthClostridium difficile and Clostridium perfringens research

Cited by 610

Massive expansion of human gut bacteriophage diversity

Camarillo-Guerrero, L. F., Almeida, A., Rangel-Pineros, G., Finn, R. D., & Lawley, T. D. (2021) · Cell

Bacteriophages and microbial interactionsEvolution and Genetic Dynamics

Cited by 594

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice

Lawley, T. D., Clare, S., Walker, A. W., Stares, M. D., Connor, T. R., Raisen, C., Goulding, D., Rad, R., Schreiber, F., Brandt, C., et al. (2012) · PLoS Pathogens

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

Cited by 540

Identification of bacteria-derived HLA-bound peptides in melanoma

Kalaora, S., Nagler, A., Nejman, D., Alon, M., Barbolin, C., Barnea, E., Ketelaars, S. L. C., Cheng, K., Vervier, K., Shental, N., et al. (2021) · Nature

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 457

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

Lawley, T. D., Clare, S., Walker, A. W., Goulding, D., Stabler, R. A., Croucher, N., Mastroeni, P., Scott, P., Raisen, C., Mottram, L., et al. (2009) · Infection and Immunity

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

Cited by 349

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

Seo, S.-U., Kamada, N., Muñoz-Planillo, R., Kim, Y.-G., Kim, D., Koizumi, Y., Hasegawa, M., Himpsl, S. D., Browne, H. P., Lawley, T. D., et al. (2015) · Immunity

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 318

The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping

Beresford-Jones, B. S., Forster, S. C., Stares, M. D., Notley, G., Viciani, E., Browne, H. P., Boehmler, D. J., Soderholm, A. T., Kumar, N., Vervier, K., et al. (2022) · Cell Host & Microbe

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 194

High-throughput analysis of gene essentiality and sporulation in Clostridium difficile

Dembek, M., Barquist, L., Boinett, C. J., Cain, A. K., Mayho, M., Lawley, T. D., Fairweather, N. F., & Fagan, R. P. (2015) · mBio

Clostridium difficile and Clostridium perfringens researchBacterial Genetics and Biotechnology

Cited by 185

A gut microbial signature for combination immune checkpoint blockade across cancer types

Gunjur, A., Shao, Y., Rozday, T., Klein, O., Mu, A., Haak, B. W., Markman, B., Kee, D., Carlino, M. S., Underhill, C., et al. (2024) · Nature Medicine

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 165

A modified R-type bacteriocin specifically targeting Clostridium difficile prevents colonization of mice without affecting gut microbiota diversity

Gebhart, D., Lok, S., Clare, S., Tomas, M., Stares, M., Scholl, D., Donskey, C. J., Lawley, T. D., & Govoni, G. R. (2015) · mBio

Clostridium difficile and Clostridium perfringens researchBacteriophages and microbial interactions

Cited by 127

Strong pathogen competition in neonatal gut colonisation

Mäklin, T., Thorpe, H. A., Pöntinen, A. K., Gladstone, R. A., Shao, Y., Pesonen, M., McNally, A., Johnsen, P. J., Samuelsen, Ø., Lawley, T. D., et al. (2022) · Nature Communications

Gut microbiota and healthEscherichia coli research studies

Cited by 54

Genomic Epidemiology of a Protracted Hospital Outbreak Caused by a Toxin A-Negative Clostridium difficile Sublineage PCR Ribotype 017 Strain in London, England

Cairns, M. D., Preston, M. D., Lawley, T. D., Clark, T. G., Stabler, R. A., & Wren, B. W. (2015) · Journal of Clinical Microbiology

Clostridium difficile and Clostridium perfringens researchAntimicrobial Resistance in Staphylococcus

Cited by 46

Geographical variation in the incidence of colorectal cancer and urinary tract cancer is associated with population exposure to colibactin-producing Escherichia coli

Mäklin, T., Taira, A., Arredondo-Alonso, S., Shao, Y., Stratton, M. R., Lawley, T. D., Aaltonen, L. A., & Corander, J. (2025) · The Lancet Microbe

Escherichia coli research studiesBacterial Cancer Therapy

Cited by 22

Genomic atlas of Bifidobacterium infantis and B. longum informs infant probiotic design

Shao, Y., Wang, S., Gichuki, B. M., Stares, M. D., Rozday, T. J., Kumar, N., Browne, H. P., Dawson, N. J. R., Njunge, J. M., Tigoi, C., et al. (2026) · Cell

Gut microbiota and healthInfant Nutrition and Health

Cited by 17

Assessment of genome evolution in Bifidobacterium adolescentis indicates genetic adaptation to the human gut

Selleri, E., Tarracchini, C., Petraro, S., Mancabelli, L., Milani, C., Turroni, F., Shao, Y., Browne, H. P., Lawley, T. D., van Sinderen, D., et al. (2026) · mSystems

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 3