Khanna, Kum Kum

DNA double-strand breaks: signaling, repair and the cancer connection

Khanna, K. K., & Jackson, S. P. (2001) · Nature Genetics

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,455

Whole-genome landscape of pancreatic neuroendocrine tumours

Initiative, A. P. C. G., Scarpa, A., Chang, D. K., Nones, K., Corbo, V., Patch, A.-M., Bailey, P., Lawlor, R. T., Johns, A. L., Miller, D. K., et al. (2017) · Nature

Neuroendocrine Tumor Research AdvancesPancreatic and Hepatic Oncology Research

Cited by 999

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

Schoenmakers, E., Agostini, M., Mitchell, C., Schoenmakers, N., Papp, L., Rajanayagam, O., Padidela, R., Ceron-Gutierrez, L., Doffinger, R., Prevosto, C., et al. (2010) · Journal of Clinical Investigation

Selenium in Biological SystemsOrganoselenium and organotellurium chemistry

Cited by 315

A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation

Hinz, M., Stilmann, M., Arslan, S. Ç., Khanna, K. K., Dittmar, G., & Scheidereit, C. (2010) · Molecular Cell

NF-κB Signaling PathwaysDNA Repair Mechanisms

Cited by 280

ATM protein kinase: the linchpin of cellular defenses to stress

Bhatti, S., Kozlov, S., Farooqi, A. A., Naqi, A., Lavin, M., & Khanna, K. K. (2011) · Cellular and Molecular Life Sciences

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 116

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Al-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., et al. (2014) · Oncogenesis

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 107

Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma

Ferrari de Andrade, L., Ngiow, S. F., Stannard, K., Rusakiewicz, S., Kalimutho, M., Khanna, K. K., Tey, S.-K., Takeda, K., Zitvogel, L., Martinet, L., et al. (2014) · Cancer Research

Melanoma and MAPK PathwaysImmune Cell Function and Interaction

Cited by 105

Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers

Nones, K., Johnson, J., Newell, F., Patch, A. M., Thorne, H., Kazakoff, S. H., de Luca, X. M., Parsons, M. T., Ferguson, K., Reid, L. E., et al. (2019) · Annals of Oncology

BRCA gene mutations in cancerCancer Genomics and Diagnostics

Cited by 93

Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells

Peters, A. A., Jamaludin, S. Y. N., Yapa, K. T. D. S., Chalmers, S., Wiegmans, A. P., Lim, H. F., Milevskiy, M. J. G., Azimi, I., Davis, F. M., Northwood, K. S., et al. (2017) · Oncogene

Ion Channels and ReceptorsCalcium signaling and nucleotide metabolism

Cited by 85

Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by α-lipoic acid

Gatei, M., Shkedy, D., Khanna, K. K., Uziel, T., Shiloh, Y., Pandita, T. K., Lavin, M. F., & Rotman, G. (2001) · Oncogene

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 68

DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer.

Hernández-Pérez, S., Cabrera, E., Salido, E., Lim, M., Reid, L., Lakhani, S. R., Khanna, K. K., Saunus, J. M., & Freire, R. (2017) · Oncogene

Ubiquitin and proteasome pathwaysMicrotubule and mitosis dynamics

Cited by 61

Multidimensional phenotyping of breast cancer cell lines to guide preclinical research

Saunus, J. M., Smart, C. E., Kutasovic, J. R., Johnston, R. L., Kalita-de Croft, P., Miranda, M., Rozali, E. N., Vargas, A. C., Reid, L. E., Lorsy, E., et al. (2018) · Breast Cancer Research and Treatment

Breast Cancer Treatment StudiesCancer Cells and Metastasis

Cited by 35

INT6/EIF3E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells

Morris, C., Tomimatsu, N., Richard, D. J., Cluet, D., Burma, S., Khanna, K. K., & Jalinot, P. (2012) · Cancer Research

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 21